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Parasitology Drugs

Terms in this set (18)

Benznidazole and Nifurtimox
trypanosoma cruzi; Effective against the acute trypomastigote stage not the amastigotes; mne- benzi for pimple like chagoma or knife it off
Suramin or Eflornithine
T. b. gambiense - West Africa
T. b. rhodesiense - East Africa
intravenous, removes tryps from everywhere
except in CNS
melarsoprol
T. b. gambiense - West Africa
T. b. rhodesiense - East Africa
crosses BBB
Amphoteracin B/Paramomycin/Miltefosine/pentavalent antimonials IV (PENTOSTAM)
Leishmaniasis; Pentostam is cheaper with more side effects
Metronidazole 'Flagyl'
GET out of the way, the metro is coming; Giardia, Entamoeba histolytica, trichomonas vaginalis
Paramomycin
Leishmania, entamoeba
chloroquine
magic bullet drug for malariae, removes all blood stages but not hypnozoite form of ovale and vivax that retains for 20-30 years
Quinine/Quinadine
reserve antimalarial, no resistance yet
Primaquine
hypnozoite stage of malaria
Sulfadoxine/Pyramethamine eflaquine/ Sulfadoxine/Pyramethamine
falciparum combination drug therapy
Artemisinin
used in combination therapy for falciparum; Artemether/lumefantrine (Coartem®)
Mefloquine (Lariam®)
Doxycycline
Chloroquine (Aralen®)
Atovaquone and proguanil (Malarone)
prophylactic malarial drugs
Prizaquantel
schistosoma, clonorchis sinesis, paragonimus, saginata, diphyllobothrium latum; treatsbladderandkidneypathology,vaccinatewaterbuffalo
Albendazole
Neurocysticercosis (with corticosteroids)/solium, Echinococcus granulosus, Hookworms, Ascaris lumbricoides, trichuris, Enterobius vermicularis, A. caninum, loa, medinense
Niclosamide
solium, saginata, Diphyllobothrium latum, Dipylidium caninum, topurge/expeltapworm,pumpkinseeds purge
benzimidazole carbamate (mebendazole)
Echinococcus granulosus, multilocularis, tri tri, trichinella,
IVERMECTIN
Ascaris lumbricoides, strongyloides, A. caninum, loa, microfilaria, all trematodes
Thiabendazole
Strongyloides, A. caninum, medinense
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