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5 Written questions

5 Matching questions

  1. Mismatch repair
  2. Okazaki fragment
  3. nucleoid
  4. bacteria
  5. helicase
  1. a A short segment of DNA synthesized away from the replication fork on a template strand during DNA replication, many of which are joined together to make up the lagging strand of newly synthesized DNA.
  2. b One of two prokaryotic domains, the other being Archaea.
  3. c A dense region of DNA in a prokaryotic cell.
  4. d An enzyme that untwists the double helix of DNA at the replication forks, separating the two strands and making them available as template strands.
  5. e The cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides.

5 Multiple choice questions

  1. An enzyme that catalyzes the elongation of new DNA (for example, at a replication fork) by the addition of nucleotides to the 3' end of an existing chain. There are several different DNA polymerases; DNA polymerase III and DNA polymerase I play major roles in DNA replication in prokaryotes.
  2. Eukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed.
  3. An isotope (an atomic form of a chemical element) that is unstable; the nucleus decays spontaneously, giving off detectable particles and energy.
  4. A virus that infects bacteria; also called a phage.
  5. An enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells.

5 True/False questions

  1. phageA virus that infects bacteria; also called a bacteriophage.


  2. DNA ligaseA linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of one DNA fragment (such as an Okazaki fragment) to the 5' end of another DNA fragment (such as a growing DNA chain).


  3. deoxyriboseThe sugar component of DNA nucleotides, having one fewer hydroxyl group than ribose, the sugar component of RNA nucleotides.


  4. nucleosomeThe basic, bead-like unit of DNA packing in eukaryotes, consisting of a segment of DNA wound around a protein core composed of two copies of each of four types of histone.


  5. chromatinThe complex of DNA and proteins that makes up a eukaryotic chromosome. When the cell is not dividing, chromatin exists in its dispersed form, as a mass of very long, thin fibers that are not visible with a light microscope.


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