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Chapter 35: Nonopioid Analgesics (ATI)
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Which medications are considered nonopioid analgesics?
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NSAID and Acetaminophen
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Terms in this set (35)
Which medications are considered nonopioid analgesics?
NSAID and Acetaminophen
First-generation NSAID (COX-1 and COX-2 inhibitors) medications
Aspirin
Ibuprofen
Naproxen
Indomethacin
Diclofenac
Ketorolac
Meloxicam
Second-generation NSAID (selective COX-2 inhibitor) medications
Celecoxib (celebrex)
What is the pharmacological action of NSAIDs?
Inhibition of cyclooxygenase
- Inhibition of COX-1 can result in decreased platelet aggregation and kidney damage.
- Inhibition of COX-2 results in decreased inflammation, fever, and pain
Therapeutic uses of NSAIDs
- Inflammation suppression
- Analgesia for mild to moderate pain, such as with osteoarthritis and rheumatoid arthritis
- Fever reduction
-Dysmenorrhea
-Inhibition of platelet aggregation, which protects against ischemic stroke and myocardial
infarction (aspirin)
