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primary lymphatic organs
red bone marrow and thymus; sites where B and T lymphocytes become immunocompetent
secondary lymphatic organs
lymph nodes, tonsils, and spleen; populated with immunocompetent lympocytes only after the cells have matured
red bone marrow
produces all classes of formed elements of the blood; involved in the hemopoiesis and immunity
member of the endocrine, lymphatic, and immune systems; houses developing lymphocytes and secretes hormones that regulate their later activity
reticular epithelial cells
seal off the cortex from the medulla and surround blood vessels and lymphocyte clusters in he cortex; develop the blood-thymus barrier; produce several signaling molecules that promote development and action of T cells
most numerous lymphatic organ; cleanse the lymph and act as a site for T and B cell activation; only lymphatic organ with afferent lymphatic vessels; especially populated in the following regions: cervical, axillary, thoracic, abdominal, intestinal, inguinal, and popliteal.
narrow relatively clear space which contains reticular fibers, macrophages, and dendritic cells
patches of lymphatic tissue located at the entrance of the the pharynx; guard against ingested and inhaled pathogens
consists of lymphocytes and macrophages aggregated along small branches of the splenic artery; cylindrical
lymph node medulla
extends to the surface of the hilum; largely branching networks of medullary cords
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