Inflammation, Organization, Regeneration
What are the three steps of tissue repair?
Macrophages, mast cells, and injured tissue cells release inflammatory chemicals
White blood cells, plasma fluid, and antibodies flow to the area
Clotting factors from plasma fluid form a clot and close and seal the wound (scab)
Blood clot is replaced by granulation tissue
Fibroblasts fill the would and secrete collagen
Macrophages digest original blood clot
Surface epithelium begins to regenerate and grows under the scab, eventually replacing it
Scar tissue from fibroblasts remain
Replacement of old tissue with the same kind of tissue
Replacement of old tissue with scar tissue (fibrous connective tissue)
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