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Inflammation, Organization, Regeneration

What are the three steps of tissue repair?


Macrophages, mast cells, and injured tissue cells release inflammatory chemicals


White blood cells, plasma fluid, and antibodies flow to the area


Clotting factors from plasma fluid form a clot and close and seal the wound (scab)


Blood clot is replaced by granulation tissue


Fibroblasts fill the would and secrete collagen


Macrophages digest original blood clot


Surface epithelium begins to regenerate and grows under the scab, eventually replacing it


Scar tissue from fibroblasts remain


Replacement of old tissue with the same kind of tissue


Replacement of old tissue with scar tissue (fibrous connective tissue)

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