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disease of the day- Pseudomonas aeruginosa
Terms in this set (23)
what are some diagnosis methods?
-grows readily in culture(oxidase positive)
-on burn patients, it turns blue or green
what are some characteristics of this disease?
-obligate aerobe(needs oxygen to grow)
-found in water, soil, and on vegetation
-rarely causes community acquired infections
how is mortality associated with virulence factors?
it is controlled by quorum sensing
what are some effective antibiotics for treatment?
-not effective against all strains
true/false: this is the most consistently resistant pathogenic bacterium(antibiotic resistant)
how is this disease antibiotic resistant?
use combination of gentamicin and carbenicillin
this is an opportunistic pathogen so it is the most common gram negative cause of what infection
what are some examples of nosocomial infections of this disease?
-surgical wound infections
-burn wound infections
what % of patients die from burn wounds?
what % of patients die from AIDs?
what % of patients die from cystic fibrosis?
what % of ventilator associated pneumonia patients die?
what are the two types of infection?
chronic and acute
what do biofilms interfere with?
immune cell access
true/false: biofilms are more resistant to antibiotics and disinfectants
how do you kill biofilms
you have to scrub it off to disrupt in order to kill it
what % of human infections are caused by biofilms
true/false: biofilms provide as an exopolysaccharide matrix for adherence
what type of infection does cell-to-cell signaling systems allow coordinate, cell density dependent production of high amounts of extracellular virulence factors
what type of infection does tissue damage by proteases and toxins leading to blood vessel invasion, dissemination, multiple-organ failure, systemic inflammatory response syndrome, and death
what type of infection takes place in cystic fibrosis patients?
what type of infection has low production of extracellular virulence factors?
describe quorum sensing
-have to have a certain # of cells to overcome autoinducer
-if reach high enough density it will go back into cell and turn on genes
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