a Y shaped point that results when the the 2 strands of DNA (double helix) seperates so that the DNA molecule can b seperated
an enzyme that catalyzes the formation of the DNA molecule, it adds nucleotides to exposed nitrogen bases.
STEP 1 of DNA replication
DNA helicases unwind the DNa strands by breaking hydrogen bonds that link complementary nitrogen bases. When seperated proteins attach to each strand to keep them apart.
Are hydrogen bonds weak or stong? Why?
Weak. It makes it easier for the DNA to unattach and break apart, making the DNA relication faster.
How does step 2 occur?
At the replication forks polymerases move along each strand, adding nucleotides to he nitrogen bases (according to base pairing rules).
STEP 3 of DNA replication
The process in step 2 ccurs until all of DNA has been copied and polymerases are signaled to detach. It produces 2 DNA molecuels composed of 1 new and 1 original strand.(nucleotide sequences are identical)
How does the DNA polymerases check for errors and fix them?
it can only add nucleotides to a growing strand if the previous nucleotide is correctly paired to its complementary base, if there is a mismatched nucleotide, it back tracks and replaces the incorrect pairing with the right one.
it states that cytosine pairs with guanine and adenine pairs with thymine in DNA. Adenine pairs with uracil in RNA
a characteristic of nucleic acids in which the sequenceof bases on one trands is paired with the other sequence of bases on a seperate strand.
James watson, and Fancis Crick
pieced together model of DNA structure, They found out that DNA molecules are composed of double helixes and each strand is made up of linked nucleotides
for each organism studied, the amount of A always equaled T and the amount of G always equaled C, the amount of each base varied between different organisms
The way x-ray diffraction works
x-rays bounce off the object and are scattered in a patteren onto a piece of film
Maurice Wilkins an Rosalind Frankiln
developed high-quality X-ray diffraction pictures of DNA strands, suggestng that it resembled a tightly coiled helix and was composed of two or three strands of nuleotides
Wton an crick determined...
that purine on one strand of DNA always goes with a pyrimidine on the opposite strand
Pairing between bases
adenine forms 2 hydrogen bonds with thymine, cytosine forms 3 hydrogen bonds with guanine
Prokaryote DNA repliaton
2 replicated forks that begin at a single point and the replicating forks move away from eachother until they meet the opposite side of the DNA circle
length of DNA makes it a challenge
the replication of a typiclal human chromosome with one pair of replication forks spreading rom a single point takes 33 days
Human chromosome replication
each chromo is replicated in 100 sections that are 100000 nucleotides long with a different starting point