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Blood bank test #2
Terms in this set (75)
What reagent do you use to confirm group O units before placing them in inventory, it should be negative?
4 degrees celcius
If all of your serum and red cell testing in ABO typing is negative, all negative agglutination reactions, incubate tubes at room temperature or ______ with an auto control.
What individuals produce anti A,B if you give them type A or B blood, it would agglutinate and cause a problem?
anti A, anti B, and anti H
what antibodies are formed by a Bombay individual. Their phenotype presents with anti A, anti B and anti A,B and a wide thermal range of anti H in the serum?
When a patient is a subgroup of what group, there is a discrepancy between cell and serum ABO grouping?
This refers to a stronger expression of antigens due to homozygosity.
This immunoglobulin class is primarily associated with ABO antibodies.
low titer isoagglutinins
In elderly patients when the forward type demonstrates as a group A and the reverse type appears as group AB, the most likely cause of the discrepancy is that the patient has what?
What are the gene products of the A and B genes?
only group O
What ABO phenotypes would be compatible with a transfusion of group O RBC's?
group AB, O,A or B
What ABO phenotypes would be compatible if the patient with group O required a transfusion of fresh frozen plasma?
In what order are the ABO phenotypes the most frequent to least frequent that occur in the white population?
What immunoglobulin class is primarily associated with ABO antibodies?
What immunodominant sugar confers B blood group specificity?
What gene controls the presence of soluble H substance in saliva?
Which lectin agglutinates A1 red cells?
What immunodominat sugar determines the specificity of H antigen?
newborn, patient with hypogammaglobulinemia, cold alloantibody
Which of the following situations may produce ABO discrepancies in the serum testing?
Weak D test
What test detects a weak d antigen?
If both the anti-d reagent and Rh control test___, you can not report out the results as you are unable to interpret without further testing.
What phenotype will react with anti-f?
If anti- E is identified in a patient, you also should check for what?
crossmatch c-negative units
If anti-f is identified in a patient and since commercial antisera is not available, you should do what to locate compatible RBC untis?
Rh negative red cells are transfused into an Rh positive patient with a genotype of CDe/CDe in an emergency situation. An antibody likely to develop would be what? Anti- e would not be formed because the recipients red cells contain the e antigens.
The Rh genotype CDE/cDE is written in Wiener notation as what?
In Rosenfield notation the phenotype of a donor may be written as Rh: 1,-2,3,4,5. What is the correct phenotype in Fisher- Race (CDE) notation?
A patient's Rh phenotype was determined to be D+,C+,e+,c-,E-. The race of this donor is most likely?
The test for the weak d antigen involves?
The anti-G antibody would be negative with which of the following red cell genotypes?
unreliable because of immunoglobulins already on the cell
Results of a weak D test on a patient with a positive DAT would be?
red cell membrane abnormalities
The Rhnull pheotype is associated with:
The blood group system that was originally identified as the Rh system is now called what?
A donor tested D-negative using commercial anti-D reagent. The antiglobulin or weak D test was positive. How should the RBC unit be labeled?
Which offspring is not possible from a mother who is R2r and a father who is R1r?
How are antibodies to the Rh system antigens usually characterized?
Which of the following genotypes is heterozygous for the c antigen?
What is the likelihood that two heterozygous D-positive parents will have a D-negative child?
Which of the following genotypes could make anti-rhi (anti-Ce)?
Red cells that phenotype as S neg s neg are also what?
This is an IgG antibody that can sensitize recipient's cells in vivo if that recipient has anti-K antibodies.
Rh antibodies are what?
coombs control cells (check cells)
this is used in AHG testing to detect false negative reactions due to inactivated anti- igG.
Antibodies in the Kidd system are what?
Antibodies in anti-M and N are what?
if a screen cell positive only at 22 degree celcius, consider ___ as being a positive antibody.
The Lewis blood group system differs because it is a system of antigens manufactured by tissue cells rather that what?
A person who inherits the Le,se, and H genes will have red cells that pheotype what?
Which blood group system possesses the Js^b and kp^a antigens?
An antibody commonly associated with delayed transfusion reactions is?
which phenotype is associated with resistance to malarial invasion?
anti-N, anti-Le^b, anti- P1
Which of these antibodies are typically Igm?
Which of the following reagents destroys the kell sysytem antigens?
Glycoprotein A and glycoprotein B passes antigen sites for which blood group system?
Select the antibody that is characteristically clinically insignificant:
absence of Kx antigen
The McLeod phenotype is associated with what?
rare in all populations
Typing is Lu(a-b-) would be considered what?
Cold autoantibodies are usually which specificity?
Individuals with p phenotype can make what?
Alleles within the Lewis system includes what?
Which of the following antibodies requires the antiglobulin test for in vitro detection?
running a ficin treated panel
What procedure would help to distinguish between an anti-Fy^a and anti JK^a in an antibody mixture?
What does anti-K1 do to IAT's?
Which of the following antigens is poorly expressed on cord blood cells?
Reagent antibody screening cells may not detect antibodies directed against low-incidence antigens. Which antibody is most likely to go undetected?
chronic granulomatus disease
Select the disease commonly associated with the McLeod phenotype?
anti-B, anti-I, and anti- Le^a
Which set of antibodies could you possibly find in a patient with no history of transfusion or pregnancy?
this organization or document accredits hospitals and inspects clinical laboratories.
this antibody is typically IgM
antibodies to this blood group system show dosage.
this antigen is rendered inactive by enzyme treatment.
A slow, gradual increase in the values obtained for a quality control analysis is indicative of a?
the frequency that fire alarms should be tested. Time frame.
Plant lectin that has specificity for the H antigen.
In a microscope the function of this is to direct the light beam onto the specimen.
this antibody is typically IgG
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