A part of a city, especially a slum area, occupied by a minority group or groups.
In WWII it was an area in Poland that was used to "quarantine" the Jews before they were shipped of to concentration camps. The Warsaw Ghetto was the largest of the ghettos in Nazi-occupied Europe, located in the territory of General Government in occupied Poland during World War II. Established in November 1940, it was surrounded by wall and contained nearly 500,000 Jews. About 45,000 Jews died there in 1941 alone, as a result of overcrowding, hard labor, lack of sanitation, insufficient food, starvation, and disease.