A client with peptic ulcer disease is taking ranitidine (Zantac). What is the expected outcome of this drug?
1. Heal the ulcer.
2. Protect the ulcer surface from acids.
3. Reduce acid concentration.
4. Limit gastric acid secretion.
Histamine-2 (H2) receptor antagonists, such as ranitidine, reduce gastric acid secretion. Antisecretory, or proton-pump inhibitors, such as omeprazole (Prilosec), help ulcers heal quickly in 4 to 8 weeks. Cytoprotective drugs, such as sucralfate (Carafate), protect the ulcer surface against acid, bile, and pepsin. Antacids reduce acid concentration and help reduce symptoms.