Parkinson's disease

Which part of the brain is affected in Parkinson's disease?

Basal ganglia

Which neurotransmitter is lacking in Parkinson's disease?

Dopamine

What are the three prodromal symptoms in Parkinson's disease?

Constipation
REM sleep disturbance
Anosmia

What is the classic triad of Parkinson's disease?

Decrementing bradykinesia
Tremor
Rigidity

What's the cardinal feature of Parkinson's disease?

Bradykinesia

What are the three Parkinson's plus syndromes?

Progressive supranuclear palsy
Multisystem atrophy
Corticobasal syndrome

What's the number one risk factor for a pt with Parkinson's disease developing dementia?

Age

Which drug is most effective?

Levodopa

What are the side effects of levodopa to be aware of?

Motor fluctuations
Impulse control disorders