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disinhibition, emotional lability, slurred speech, ataxia. SERUM GAMMA-GLUTAMYLTRANSFERASE (GGT). Treatment is naltrexone and disulfiram
Tremor, tachycardia, hypertension, malaise, nausea, seizures, delerium tremens, tremulousness, agitation, HALLUCINATIONS (INCLUDING TACTILE). Tx for DT is benzodiazepines
CNS depression, nausea and vomiting, constipation, pupillary constriction, seizures. Tx is naloxone and naltrexone
anxiety, insomnia, anorexia, sweating, dilated pupils, piloerection, fever, rhinorrhea, stomach cramps and diarrhea, yawning. Treatment is naloxone+ buprenorphine and methadone
greater safety margin. Amnesia, ataxia, somnolence, minor respiratory depression. Additive effects with alcohol. Treatment is flumazenial
psychomotor agitation, impaired judgement, pupillary dilation, hypertension, tachycardia, euphoria, prolonged wakefulness and attention, cardiac arrhythmias, delusions, hallucinations, fever
post-use crash including depression, lethargy, headache, stomach cramps, hunger, hypersomnolence
euphoria, psychomotor agitation, impaired judgement, tachycardia, pupillary dilation, hypertension, HALLUCINATIONS (INCLUDING TACTILE), paranoid ideations, angina, sudden cardiac death. Treatment is benzodiazepines
post-use crash including severe depression and suicidality, hypersomnolence, fatigue, malaise, severe psychological craving
restlessness, insomnia, increased diuresis, muscle twitching, cardiac arrhythmias
irritability, headache, weight gain, craving. Treatment is bupropion/varenicline
BELLIGERENCE, impulsiveness, fever, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, homicidality, psychosis, delerium
Depression, anxiety, irritability, restlessness, anergia, disturbances of thought and sleep
Marked anxiety or depression, delusions, visual hallucinations, FLASHBACKS, pupillary dilation
Euphoria, anxiety, paranoid delusions, perception of slowed time, impaired judgment, social withdrawal, increased appetite, dry mouth, hallucinations
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