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21 terms

intoxication and withdrawal

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alcohol intoxication
disinhibition, emotional lability, slurred speech, ataxia. SERUM GAMMA-GLUTAMYLTRANSFERASE (GGT). Treatment is naltrexone and disulfiram
alcohol withdrawal
Tremor, tachycardia, hypertension, malaise, nausea, seizures, delerium tremens, tremulousness, agitation, HALLUCINATIONS (INCLUDING TACTILE). Tx for DT is benzodiazepines
opioid intoxication
CNS depression, nausea and vomiting, constipation, pupillary constriction, seizures. Tx is naloxone and naltrexone
opioid withdrawal
anxiety, insomnia, anorexia, sweating, dilated pupils, piloerection, fever, rhinorrhea, stomach cramps and diarrhea, yawning. Treatment is naloxone+ buprenorphine and methadone
Barbiturate intoxication
Low safety margin, RESPIRATORY DEPRESSION
barbiturate withdrawal
anxiety, seizures, delerium, life threatening cardiovascular collapse
benzodiazepine intoxication
greater safety margin. Amnesia, ataxia, somnolence, minor respiratory depression. Additive effects with alcohol. Treatment is flumazenial
benzodiazepine withdrawal
rebound anxiety, seizures, tremor, insomnia
amphetamine intoxication
psychomotor agitation, impaired judgement, pupillary dilation, hypertension, tachycardia, euphoria, prolonged wakefulness and attention, cardiac arrhythmias, delusions, hallucinations, fever
amphetamine withdrawal
post-use crash including depression, lethargy, headache, stomach cramps, hunger, hypersomnolence
cocaine intoxication
euphoria, psychomotor agitation, impaired judgement, tachycardia, pupillary dilation, hypertension, HALLUCINATIONS (INCLUDING TACTILE), paranoid ideations, angina, sudden cardiac death. Treatment is benzodiazepines
cocaine withdrawal
post-use crash including severe depression and suicidality, hypersomnolence, fatigue, malaise, severe psychological craving
caffeine intoxication
restlessness, insomnia, increased diuresis, muscle twitching, cardiac arrhythmias
caffeine withdrawal
headache, lethargy, depression, weight gain
nicotine intoxication
restlessness, insomnia, anxiety, arrhythmias
nicotine withdrawal
irritability, headache, weight gain, craving. Treatment is bupropion/varenicline
PCP intoxication
BELLIGERENCE, impulsiveness, fever, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, homicidality, psychosis, delerium
PCP withdrawal
Depression, anxiety, irritability, restlessness, anergia, disturbances of thought and sleep
LSD intoxication
Marked anxiety or depression, delusions, visual hallucinations, FLASHBACKS, pupillary dilation
Marijuana intoxication
Euphoria, anxiety, paranoid delusions, perception of slowed time, impaired judgment, social withdrawal, increased appetite, dry mouth, hallucinations
Marijuana withdrawal
irritability, depression, insomnia, nausea. Most symptoms peak in 48 hours and last for 5-7 days. Can be detected in urine up to 1 month after last use