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Cardiovascular drugs - 2
Terms in this set (54)
__ and ___ are ACE (Angiotensin converting enzyme) inhibitors.
___ prevent formation of angiotensin II. This causes arterial vasodilation, reduced fluid retention, and reduced afterload.
___ is a Ca channel blocker that causes arteriodilation. It is used to treat hypertension in cats.
___ acts directly to relax arterial smooth muscle, causing vasodilation and reducing afterload.
___ causes smooth muscle relaxation and venodilation to reduces preload. It is used in critical cases especially in patients with pulmonary edema due to elevated venous pressure
___ is available as a topical cream that is applied to the inside of the ear pinna. Wear gloves.
___ is a short-acting vasodilator with a half life of less than one hour.
___ selectively causes pulmonary vasodilation to relieve pulmonary hypertension.
___ is a vasodilator that can be used long-term.
___ is known in human medicine as viagra.
___ Increases availability of Ca in the heart, causing increased contractility. It decreases availability of Ca to the smooth muscles, causing arterial/venous vasodilation, which results in increased stroke volume and cardiac output.
___ is a positive inotrope used in patients with systolic failure (Congestive heart failure, Dilated cardiomyopathy)
___ is derivied from digitalis, an extract from the foxglove plant.
___ is a positive inotrope that blocks the Na/K pump to make Ca more available. This increases myocardial contractility, improves stroke volume, and reduces sympathetic stimulation, which normalizes BP and slows HR
___ is a positive inotrope used to manage congestive heart failure in dogs and cats.
___ has variable absorption and a narrow margin of safety. Vomiting and anorexia are the first signs of toxicity.
___ is a positive inotrope with a half life of over 24 hours.
___ is a vailable both as a tab and an elixir. The elixir has a better bioavailability. Give on an empty stomach to improve absorption.
Because of the risk of toxicity, it is crucial not to exceed the prescribed dose of ___.
___ is a sympathomimetic (beta 1 agonist) that acts as a positive inotrope. It is used in emergency and critical care cases and to increase cardiac output of anesthatized patients.
___ is a positive inotrope with a half life of less than two minutes. it is only effective as an IV.
___ is a sympatholytic (beta 1 blocker) that acts as a negative inotrope. It is used to treat hypertrophic cardiomyopathy and also acts as an antiarrhythmic.
A class 1(b) antiarrhythmic that is used in emergencies to control PVCs (premature ventricular contractions) and prevent progression to ventricular fibrillation.
___ is available in combination with epinephrine for use as a local anesthetic. DO NOT USE this combination for arrhythmias!
___ is a class 1(a) antiarrhythmic that is used for long-term management of atrial and ventricular arrhythmias.
_____are class 2 antiarrhythmics that are used to treat atrial fibrillation as well as tachycardia in boxers. They also act as negative inotropes.
___ is a class 3 antiarrhythmic used to treat tachycardia. It is a fairly new drug with limited information on effectiveness and adverse effects.
___ is a class 4 antiarrhythmic used for long-term management of atrial fibrillation and tachyarrhythmias. It can also be used as negative inotrope for hypertrophic cardiomyopathy
___ is a sympathomimetic CPR drug.
A Parasympatholytic CPR drug that blocks vagal stimulation.
___ is a CPR drug that can also be used to reverse AV block and SA bradycardia associated with digoxin overdose.
Vasopressin (Antidiuretic hormone)
___ is a CPR drug that causes vasoconstriction and increased blood pressure to help maintain renal flow. It can be used alone or with epinephrine.
___ is a class 1(b) short-acting antiarrhythmic that is also used as a CPR drug to stabilize the myocardium before defibrillation.
___ is an opioid antagonist CPR drug that reverses CNS/cardiac depressant effects of opioid analgesics.
___ antiarrhythmics are sodium channel blockers that inhibit depolarization
___ antiarrhythmics are beta adrenergic blockers that slow the heart rate.
___ antiarrhythmics are potassium channel blockers that delay repolarization.
___ antiarrhythmics are calcium channel blockers that slow conduction. Also act as negative inotropes.
___ is administered as a tablet in dogs, cats, and horses.
___ is a vasodilator that blocks calcium channels. It also acts as a negative inotrope.
___ is used to treat hypertension in cats.
___ is a vasodilator that causes arterial smooth muscle relaxation. Side effects include stimulation of the RAAS.
___ is available is a vasodilator available as an oral suspension used extra-label.
___ is an inotrope that is eliminated in the feces.
Digoxin is metabolized in the ___ and eliminated by the ___.
This inotrope is is used to treat hypertrophic cardiomyopathy. It is eliminated in its active form in the feces.
Lidocaine is administered as a(n) ___
Sustained release tablets
Procainamide, Dilitiazem are available as ___.
___ is/are metabolized by the liver and eliminated by the biliary ducts.
___ is metabolized by the liver and eliminated in the urine.
___ cannot be administered through the same catheter as other drugs,
___ may occur with use of Atenolol, Propranolol, carvediol
Atenolol, dilitiazem, propranolol, and carvediol function as both ___ and ___.
IV, IT, IO
Epinephrine is administered _, _, or _..