Laboratory test Part 2 & 3

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what would increased acid phosphatase (PAP) indicate?
prostatic carcinoma
what would reversed A/G ration indicate?
Multiple myeloma
what would increased alkaline phosphatase indicate?
1. osteoblastic lesion
2. hepatic disease
3. HPT
what would increase amylase indicate?
acute pancreatitis
what does ANA (FANA) indicate?
collagen disease (SLE, Scleroderma)
what does increased ANtistreptolysin- O (ASO) title indicate?
1. Rheumatic Fever
2. Acute Glomerulonephritis
what does increased direct bilirubin indicate?
1. hepatitis
2. duct obstruction
what does increased indirect bilirubin indicate?
hemolytic disease
what does increased BUN indicate?
1. renal disease
2.dehydration
3. hypotension
4. urinary tract obstruction
what does decreased BUN indicate?
1. hectic disease
2. pregnancy
what does increased calcium indicate?
1. muscle weakness
2. hyperparathyroidism
3. hypervitaminosis D
4. metastatic dz
what does decreased calcium indicate?
1. muscle tetany
2. chvostck's sign
3. renal failure
4. malnutrition
CK BB
brain tissue
CK MB
myocardial tissue
CK MM
skeletal muscle
what does increased CPK mean?
muscle necrosis
increased creatine
1. kidney disease
2. hypovolemic shock
decreased creatine
muscular dystophies
increased C- reactive protein
tissue necrosis
infection
RA
ELISA
screening for aids
increased ESR
infection, RA, TP, temporal arteritis, MM
decreased ESR
sickle cell anemia, polycythemia
Fluorescent treponema antibody (FTA)
present with syphillis
increased glucose in blood?
DM , bushings, renal/ liver dz
decreased glucose in blood?
insulin overdose, addison's , starvation
decrease glucose (CSF)
meningitis, acute pyogenic infection
gamma glutamyl transferase (GGT)
liver cell dysfunction and alcohol induced liver disease
Glucose tolerance test (GTT)
used for diabetic testing
glycoselated hemoglobin
tests ability to utilize glucose over 2-3 month period
hetrophile (paul bunnel )
Mono
viral meningitis
increased HCG
1. hydatiform mole
2. choriocarcinoma
3. seminoma
4. multiple pregnancy
5. tesicular teratoma
decreased HCG
1. ectopic pregnancy
2. threatened abortion
HLAB27
marker on the 6th chromosome from birth

AS, reiters, PA, eneropathic arthritis
increased HDL cholesterol
low risk of CAD
decreased HDL cholesterol
high risk of CAD
increased I-131 uptake
hyperthyroidism
endemic goiter
decreased I-131 uptake
hypothyroidism
thyroid cancer
immunoelectrophoresis
M-spike indicates multiple myeloma
ketones
diabetic acidosis
starvation
increase LDH
MI, CHF, muscular dystrophy
decrease LDH
cancer therapy
increase lipase
acute pancreatitis
increase lipids (cholesterol)
early starvation
DM
decrease lipids (cholesterol)
late starvation
liver disease
increase lipids (triglycerides)
hyperlipidemia
DM
atherosclerosis
decrease lipids (triglycerides)
cirrhosis
malabsorption
LE cell
active SLE
increase phosphorus
acromegaly
kidney dz
hypervitaminosis D
decrease phosphorus
rickets
hypovitaminosis D
hyperparathyroidism
increase protein
MM
diabetic acidosis
decrease protein
liver dz
kidney syndromes
increase protein (CSF)
viral meningitis
increased prothrombin time
vit k def
hepatocellular disease
+ RA latex
RA, SLE, cancer, sjogren, still dz
increase SGOT/ AST)
MI
liver conditions
muscular dystrophies
increase SGPT/ALT
hepatitis
MI
increase T3 ,T4
hyperthyroidism
pregnancy
decrease T3, T4
cirrhosis
hypothyroid
treponema pallidum immobilizing
syphilis
increased uric acid
gout
renal failure
VDRL
serologic screening for syphilis
western blot
specific for aids