Localized pruritic, erythematous, papular rash at site of larval penetration
Pulmonary symptoms with eosinophilia, abdominal pain with diarrhea
Asymptomatic, fluctuating eosinophilia, recurrent rash - buttocks, perineum
Due to increased generation of filariform larvae from impaired CMI.
Risks: corticosteroid use, other immunosuppressive drugs, hematologic malignancy, severe malnutrition, HTLV-1 infection, rarely HIV.
Increased larvae in intestines and lungs: GI ulcerations/hemorrhage, pneumonitis and hemoptysis. Can have secondary bacterial infections.
Disseminated disease: involve organs outside of autoinfection cycle