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Terms in this set (13)
ACE inhibitors and ARBs differ in what way? (HINT: Side Effects)
ARBs pose a lesser risk of
than ACE inhibitors but may have a higher risk of cancer.
What does ARB do?
pretty much the same as an ACE inhibitor
-Reduces the risk of stroke
-prevents occurrence of A.Fib
suffix ending for ARB's ?
Mechanism of action
-Blocks access of angiotensin II to its receptors
-Vasodilation in veins and arterioles
-Prevention of pathological changes in the heart
-Decrease release of aldosterone resulting in renal excretion of sodium and water
-HT (reduces blood pressure)
-Heart failure (only 2 ARBs approved)
-Diabetic nephropathy (2 approved ARBs--delay development and slows progression)
-Stroke prevention (losartan)
-Prevention of diabetic Retinopathy in type 1 diabetics
-Renal failure in patients with bilateral renal artery stenosis or stenosis of an artery to a single working kidney
-Increase hypotensive effects if used with other antihypertensive agents
Which two ARB's are approved for heart failure?
Valsartan (Diovan) and Candesartan (Atacand)
Which ARB is good for reducing cardiovascular mortality in post-MI patients?
Which ARB is the only ARB approved for stroke prevention?
ALL ARB's are approved for treatment of ________________.
T or F: It is okay for a pregnant woman to keep taking ARB's during her first trimester but treatment must be stopped during second and third trimesters.
ARB's (and ACE's) can cause serious fetal harm in any trimester. Therapy must be stopped as soon as pregnancy is known.
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