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Terms in this set (80)
Over what are is there a higher risk for oral cancer?
What virus is slighty linked to oral cancer?
How many month before starting anticancer therapy should a dental exam be completed?
What virus is slighty linked to oral cancer?
When was the golden age of medical oncology when the new drugs, anthrocyclines and platinum compounds were developed?
What do cancer cells fail to undergo?
What are the 2 anticancer drugs that are given IM?
What type of activation do cyclophosphamide, doxorubicin, daunorubicin and other have?
What drug is activated by intracellular phosphorylation?
What is traditional dosing of chemotherapeutics based on?
What type of drugs are alkylating agents, platinum compounds, mitomycin C, dactinomycin?
What part of cell cycle do vinca alkaoids and taxanes work on?
What drug works on the G2 phase of the cell cycle?
What part of the cell cycle do antimetabolities, topotisomerase inhibitors work on?
What synthesis does pentostatin work on?
What drug damages DNA and prevents repair?
What is inhibited by the vinca alkaloids and the taxanes?
What was the first drug used to treat cancer and is now mainly used to treat hodgkins and nonhodgkins lymphoma?
What is the most widely used drug in clinical therapy for treatment of cancer today? Needs to go through the liver to be activated
What type of agents are melphalon, busolfan, procarbazine?
What drugs are analogues of normal metabolites and act by competition, replacing the natural metabolie and then subverting cellular processes?
What is the main folic acid antagonist that we should know?
What phase of the cell cycle is methotrexate active?
What is a major side effect of methotrexate?
What type of drugs are 5-fluorouracil and cytarabine?
What drug is a cytotoxic antibiotic that binds to double stranded DNA and inhibits RNA synthesis?
What type of drugs are vincristine and vinblastine?
What phase of the cell cycle do the vinca alkaloids work?
What is the drug we talk about that is a hormonal oncologic?
What does etoposide inhibit?
Is hydroxyurea well absorbed?
What type of steroids inhibit the growth of lymphoid and blood cancers?
What hormone antagonist is indicated for breast cancer?
What hormone is used for prostatic cancer?
What drug inhibits ribonucleotide reductase and works mainly on the S phase?
What do the toxic side effects of anticancer drugs limit?
Are bone marrow, gut mucosa and hair follicles rapidly dividing cells?
Where are some side effects seen with anthracyclines?
Where are some side effects seen with platinum compounds?
Where are some side effects seen with microtubule agents?
What is the side effect with 5-flurouracil?
What is the side effect with methotrexate, etoposide and ara C?
What drug can lead to irreversible cardiomyopathy?
What side effect can be caused by busulfan, methotrexate, and bleomycin?
What 2 drugs don't cause bone marrow suppression?
What is the major side effect of cis-platinum and streptozotocin?
What is the acronym for the combo therapy of nitrogen mustard, vincristine, procarbazine and prednisone?
bone marrow suppression
What is the main lethal side effect of chemotherapy?
What part of the pituitary do ADH and oxytocin come from?
What condition is treated with somatrem, somatropin?
What drug inhibits the release of growth hormone?
What is a growth hormone antagonist drug?
What is used to inhibit prolactin?
What is the name of the synthetic T4?
What is the name of the synthetic T3?
What is the combodrug that contains both t4 and t3?
Do thyroid hormones increase heart rate?
What type of drugs are propylthiouraci, methimazole, and carbamizole?
What are the two classes of insulin secretagogues?
What type of drugs are glimepiride, glipizide, glyburide?
What type of drugs are repaglinide, nateglinide?
What is the biguanide drug that targets the liver to decrease the amount of glucose produced?
What type of drugs are rosiglitazone, and pioglitazone? They bind to peroxisome proliferator activate receptor gamma in muscle fat and liver to decrease insulin resistance?
What enzyme is inhibited by acarbose and miglitol?
What increases insulin release from beta cells and decreases release of glucagon from alpha cells?
What type of insulins are regular, aspart, lispro and glulisine?
What type of insulins are NPH, glargine, detemir?
What are 2 drugs that are used to relax uterine muscles and are beta 2 agonists?
What are 2 drugs that are uterine stiumulants?
What type of drugs are clomiphene and urofollitropin?
Which subcript of arachidonic acid analogs is active in the body? It has 4 double bonds
weight gain, sleepy
What are the 2 main side effects of antihistamines?
What class of antihistamines are diphenhydramine, doxylamine and clemastine?
What class of antihistamines are tripelennamine, pyrilamine and thonzylamine?
What class of drugs shouldn't be given to old man with BPH?
What class of antihistamines are dex, brom, chlorpheniramine and triprolidine? Makes people nervous
What class of antihistamines are hydroxyzine, cetirizine, buclizine, diphenylpyraline?
What are the 2 drugs that work on the late phase of the allergic response?
What class of antihistamines are cyproheptadine, phenindamine?
What type of drugs are beta 2 agonists, muscarinic antagonists, methylzanthines, theophalyn, theobromine caffine?
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