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What happens during initiation?
Ectoderm lining stomodeum gives rise to the oral epithelium and then to the dental lamina, adjacent to deeper ectomesenchyme, which is influenced by the neural crest cells. Both tissues are seperated by a basement membrane
What happens during the bud stage?
Growth of the dental lamina into bud that penetrates growing ectomesenchyme
What happens during the cap stage?
Enamel organ forms into cap, surrounding mass of dental papilla from the ectomesenchyme and surrounded by mass of dental sac also from the ectomesenchyme. Formation of the tooth germ.
What happens during the bell stage?
Differentiation of enamel organ into bell with four cell types and dental papilla into two cell types.
What is the important acelluar structure that seperates the oral epithelium and the ectomesenchyme?
the basement membrane
The stage named for extensive proliferation of the dental lamina into oval masses penetrating into the ectomesenchyme?
The bud stage
The buds of the dental lamina, together with the surrounding ecto mesenchyme, will develop into what?
What happens to the thickened non tooth producing portions of the dental lamina eventually?
it disintegrates as the developing oral mucosa comes to line the oral cavity
In the cap stage the tooth bud does not grow, what happens?
there is unequal growth in different parts of the tooth bud
Where is the dental papilla originally derived from?
the ectomesenchyme, which was influenced by the neural crest cells
What is the site for the future dentioenamel junction?
the basement membrane that seperates the enamel organ and dental papilla
The remaining ectomesenchyme surrounding the outside of the enamel organ condenses into what?
the dental sac
Where does the primordium of the permanent dentition develop?
the successional dental lamina, an extension of the dental lamina that extends out lingually to the primary tooth germs
What are succedaneous teeth?
permanent teeth formed with primary predecessors, the anterior teeth and the premolars
What are the cell layers found in the enamel organ in the bell stage?
the outer enamel epithelium, the inner enamel epithelium, the stellate reticulum, and the stratum intermedium
What are the 2 layers in the dental papilla within the concavity of the enamel organ?
the outer cells of the dental papilla and the central cells of the dental papilla
What will the outer cells of the dental lamina differentiate into?
dentin secreting cells (odontoblats)
What happens during the appositional stage?
the enamel, dentin, and cementum are secreted in successive layers
What is matrix?
an extracellular substance that is partially calcified, yet serves as a framework for later calcification
What conveys communications between the cells of the enamel organ, the dental papilla, and the dental sac allowing tissue interactions?
the basement membrane
When the inner epithelial epithelium columnar cells elongate and repolarize they differentiate into what?
What do the odontoblasts do?
dentinogenesis, which is the apposition of dentin matrix, or predentin, on the other side of the basement membrane
Do odontoblasts start their secretion of matrix before the ameloblasts?
yes, this is why the dentin is thicker in the mature tooth structure than the enamel
What causes the induction of the preameloblasts to differentiate into ameloblasts?
the disintegration of the basement membrane allows the preameloblasts to come into contact with the newly formed predentin
Where is the enamel matrix secreted from by the ameloblasts?
the Tomes' process, a tapered portion of each ameloblast that faces the disintegrating basement membrane
Odontoblasts leave attached cellular extensions in the length of the predentin called what?
What are the odontoblastic processes is contained in what?
a mineralized cylinder, the dentinal tubule
What cell bodies are involved in the eruption and mineralization process but will be lost after eruption?
When does the process of root development take place?
after the crown is completely shaped and the tooth is starting to erupt into the oral cavity
What is the function of the Hertwig's epithelial root sheath?
to shape the root (or roots) and induce dentin formation in the root area so that it is continuous with coronal dentin
When root formation is completed the portion of the basement membrane disintegrates its cells may become what?
epithelial rests of Malassez
When the undifferentiated cells of the dental sac come into contact with the root dentin they differentiate into what?
What are the etiological factors for anodontia?
hereditary, endocrine dysfunction, systemic disease, excess radiation exposure
What are the clinical ramifications of anodontia?
may cause disruption of occlusion and aesthetic problems, may need partial or full dentures, bridges, and/or implants
What are the clinical ramifications of supernumerary teeth?
occurs commonly between the maxillary centrals, distal to the 3rd molars and premolar region. may cause crowding, failureof normal eruption and disruption of occlusion
What are the etiological factors for micro/macrodontia?
hereditary in localized form. endocrine dysfunction is complete
What are the clinical ramifications of micro/macrodontia?
commonly involves permanent maxillary lateral incisor and 3rd molars
What are the clinical ramifications of dens in dente?
commonly affects the permanent maxillary lateral incisor. tooth may have deep lingual pit and need endodontic therapy
What are the developmental disturbances of the cap stage?
dens in dente, gemination, tubercle, and fusion
What are the clinical ramifications of gemination?
large single rooted tooth with one pulp cavity and exhibits "twinning" in crown area. normal number of teeth in dentition. may cause problems in appearance and spacing
What are the clinical ramifications of fusion?
large tooth with two pulp cavities. one fewer tooth in dentition. may cause problems in appearance and spacing
What are the development disturbances of the apposition and maturation stages?
enamel pearl, enamel dysplasia, and concresence
What are the clinical ramifications of enamel dysplasia?
pitting or intrinsic color changes in enamel. changes in thickness of enamel possible. problems in function and aesthetics
After the enamel apposition ceases the crown area of each primary or permanent tooth what happens?
the ameloblasts place an acellular dental cuticle on the new enamel surface
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