Part IV - Blood ~ cont. II
Terms in this set (25)
Fat- soluble steroid alcohol needed to make bile acids, cell membranes & sex hormones. It is a major risk factor for coronary heart dz
DM & atherosclerotic tendencies
Cholesterol & Trigs increased in:
Cholesterol & Trigs decreased in:
Microscopic identidfication of a neutrophil that has ingested a modified nucleus from another neutrophil. this occurrence requires the presence of the LE factor probably an anti body in thepatient. 50-70% of the active cases of SLE can be detected from this test. A false positive may result if the patient has a collagen dz.
Prothrombin is a protein produced by the liver & utilized for blood clotting. Adequate vitamin K is essential during the clotting process to convert prothrombin to thrombin. Prothrombin time indirectly measures the ability of the blood to clot & directly measures a defect in stage II of the clotting mechanism. This is useful in the management of anticoagulant therapy.
Increased in: Vit K def, hepatocellular dz
vitamin K def, hepatoceullular dz
Promthrombin time increased in:
RA latex is found in the blood of those w/out RA.
The titers are higher in those w/:
reed sternberg cell
The characteristic picture of Hodgkin's dz shows these cells. They are large multinucleated lymphocytes.
SGOT (serum glutamic oxloacetic transaminase) aka AST (aspartate amino transferase)
Enzyme associated w/ necrosis of the heart, liver, skeletal muscle, kidneys & other tissues. It is most absent from blood serum. Following an infarct the enzyme is released into the blood.
Increased in: MI, destructive liver conditions, muscular dystrophies
MI, destructive liver conditions, muscular dystrophies
SGOT aka AST increased in:
SGPT (serum glutamic pyruvic transaminase) aka ALT (alanine amino transferase)
Present in liver & muscle tissue. Primarily used to indicate liver dz.
Increased in: MI, hepatitis
SGPT aka ALT increased in:
More active in influencing metabolic rate than T-4.
Increased in : hyperthyroidism
Decreased in: hypothyroidism
Thyroxine is the principle thyroid hormone stored in the thyroid. Almost all thyroid hormones in the blood are bound to proteins
The end product of purine metabolism, uric acid is a metabolite of nucleic acid degeneration. It is used primarily as an aid in the dx of gout. Diet has an effect on uric acid only on a long-term basis. The amount of increase is not directly related to the severity of gout.
western blot aka IFA (indirect fluorescent antibody)
Specific, expensive & less likely to present false positives than other tests
A screening test used on those who are taking or giving blood to rule out the possibility of AIDS. 2 positive tests are necessary before ordering a Western blot test. The dx of AIDS is based on symptoms, decreased T-helper cells & the presence of uncommon opportunistic infections & tumors as well as positive blood tests.
comprehensive metabolic profile
Evaluates cardiac, bone & liver functions.
Na, K, C1, Co2, BUN, Albumin, Alk pohs, ALT/SGPT, Glucose, Total Protein, Total Bilirubin, SGOT/AST, Creatinine
complete blood count
RBC count, WBC count, Platelet count, Hemoglobin, Hematocrit, Differential, MCV, MCH, MCHC
red blood cells
Main purpose is to carry o2 from lungs to body tissues & transfer carbon dioxide from the tissues to the lungs. This is accommplished by hemoglobin in the RBC.
Decreased in anemias
RBC, Hematocrit & hemoglobin decreased
RBC quantity decreased
RBC, Hematocrity, hemoglobin & MCV decreased
Are associated w/ phagocytosis & antibody activity
Increased in: infection, malignancy
infection & malignancy
WBCs increased in:
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Part IV - special tests
Part IV - blood continued
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Part IV - kidney, ureter, bladder etc