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5 Written questions

5 Matching questions

  1. montelukast, zafirlukast
  2. iron- dextran, iron- sucrose
  3. griseofulvin
  4. phentolamine
  5. amiodarone
  1. a class III antiarrhythmic. prolongs refractory period and slows AV conduction. serious side effects (thyroid, lungs, liver)
  2. b Non-selective alpha 1+2 adrenoreceptor blocker in smooth muscle. Vasodilation. Used in phaeochromocytoma (HT due to adrenal tumor) and erectile dysfunction. SEs: first dose syncope, postural hypotension, reflex tachycardia, urinary urgency,
  3. c parenteral iron therapy (IM or IV). Indications: unable to absorbe oral iron in iron deficiency. SEs: fever, arthralgia, nausea, abdominal cramps, vomiting
  4. d antifungal that targets nuclear division (inhibits microtubules)
  5. e leukotriene receptor antagonists (preventers for asthma)

5 Multiple choice questions

  1. Antiplatelet. Monoclonal antibody that antagonises GIIb/a receptor on platelets, prevents binding of fibrinogen to platelets. Hospital use only.
  2. mast cell stabilisers (preventers for asthma)
  3. an imidazole antifungal (targets ergosterol synthesis via 14-aemethylase) - only used topically (vaginal/ skin)
  4. short term nitrate for angina, given sublingually and transdermally
  5. class of drugs for angina, reduce oxygen demand by reducing heart rate e.g. atenolol, metoprolol, propanolol

5 True/False questions

  1. sargramostimGM-CSF. Used to treat neutropenia in chemotherapy and after bone marrow transplant.

          

  2. baclofenGABA agonist used for Huntington's disease.

          

  3. bosentanEndothelin (vasoconstrictor) receptor antagonist (mixed ETa and ETb antag, vasodilatory). Not effective in primary hypertension, used in pulmonary hypertension.

          

  4. tinidazole, metronidazoleAntiprotozoal e.g. amoebiasis, giardiasis, trichomoniasis. Also used for some bacterial anaerobes. Nitroimidazoles, interfere with DNA synthesis. e.g. trichomonas vaginalis

          

  5. polyenesclass of antifungal cell membrane synthesis inhibitors. Target ergosterol synthesis via 14-aemethylase

          

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