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Immune System 2

Section 2 Worksheet
STUDY
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2 major anatomical parts of the immune system
1) Specialized immune cells (ex. leukocytes)
2) Lymphoid organs and tissues (ex. bone marrow)
Cells of the immune system originate in ________. These cells are called ______ when traveling in the blood and are classified according to the shape of their nucleus and the colors of their granules when stained.
Bone marrow, leukocytes
Neutrophil
Multilobed nucleus
Pale-staining granules
Lymphocyte
Small leukocyte, round nucleus
No prominent granules
Monocyte
large leukocyte, U-shape nucleus
no prominent granules
Eosinophil
Bilobed nucleus with granules
No prominent granules
Basophil
Large granules hide lobed nucleus
stains blue/purple
Phagocytes
Neutrophils (blood
Macrophages (tissue)
Antigen-presenting cells
Dendritic cells (tissue)
Macrophages (tissue)
B cells (blood)
Effector Cells of adaptive immunity
B and T cells (blood)
Other Specialized Immune Cells
Mast Cells (tissue)
Both B and T cells originate from _______.
Bone Marrow
The B cells mature in the _________.
Bone marrow
The T cells mature in the ________.
Thymus
Secondary Lymphoid Organs
A) Lymph nodes
B) Spleen
C) Peyer's patches
D) Appendix
E) Tonsils
3 Parts of the Lymphatic System
1) Lymphatic Vessels
2) Lymph
3) Lymph Nodes
How many liters or interstitial fluid is returned to the cardiovascular system per day?
3 L/Day
If lymphatic vessels do not function properly, there will be a buildup of fluid in the tissues. This condition is called ________.
Lymphedema
The lymphatic capillaries have ______ valves to collect the excess interstitial fluid and any leaked proteins.
One-way
The lymph is filtered through the _________ where antigens and pathogens are removed and the immune system can be activated.
Lymph Nodes
Special lymphatic capillaires in the intestines, called ______, transport absorbed ______ from the intestines into the blood.
Lacteals, Fat
2 Functions of the lymph nodes
1) removal of antigens and other debris
2) activation of the immune system (B and T cells)
While _____ lymphatic vessels carry lymph from the tissues to the lymph nodes, _______ vessels carry cleansed lymph away from the lymph nodes.
afferent, efferent
___ cells are found in the germinal centers of lymphoid follicles, and ____ cells wander through the deep _____, searching dendritic cells for their special antigen.
B, T, Cortex
3 Functions of the Spleen
1) Removes pathogens, aged erythrocytes and platelets
2) Stores platelets and breakdown products of erythrocytes
3) Site for activation of the immune system
MALT
mucosa-associated lymphoid tissue
-peyer's patches, tonsils, appendix
-respiratory system
The ______, a primary lymphoid organ, is the site for differentiation of lymphocytes into mature T cells.
Thymus
What happens to the thymus as we age?
The thymus decreases in size and activity