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Major human mineralcorticoid is --- (zona glomerulosa):
-Increases absorption (GI) and reabsorption (kidney) of Na+ with Cl-; bicarbonate and water following it
-promotes excretion of K+ H+ (secretion in kidney)
Hypersecretion from adrenal tumor produces ---:
-high blood pressure caused by retention of Na+ and resultant increase in plasma volume
major human glucocorticoid is ---:
Key function is regulation of metabolism during stress
-increases rate of protein catabolism and lipolysis
-provides resistance to stress by making nutrients available
-Raises blood pressure by vasoconstriction
-Has anti-inflammatory and immunosuppressive action
-reduces release of histamine from mast cells
-decreases capillary permeability
-inhibits white blood cells
-Hypersecretion of glucocoritcoids
-Redistribution of fat to face
-Spindly arms and legs due to muscle loss
-Poor wound healing
-Hyposecretion of glucocorticoids and aldosterone
-Hypoglycemia, muscle weakness, low blood pressure
-Dehydration due to decreased Na+ in blood
-Mimics skin darkening effects of MSH
-Potential cardiac arrest
Small amount of weak androgens (male hormones) produced
-Insignificant in males
-May contribute to sex drive in females
-converted to a form of estrogen in postmenopausal women
-Chromaffin Cells receive direct innervation from sympathetic nervous system
-develop from same tissue as postganglionic sympathetic neurons
-acts as a modified sympathetic ganglion
-Produce 80% of epinephrine (adrenaline) and 20% norepinephrine (noradrenaline)
-Hormones are sympathomimetic
-effects mimic those of sympathetic NS
-cause fight-flight behavior
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