NAPLEX 2017 Bits n Pieces

What is the equation for quickly calculating someone's estimated total cholesterol (given their LDL, HDL, and TGs)
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What is the equation for quickly calculating someone's estimated total cholesterol (given their LDL, HDL, and TGs)
HDL + LDL + (TG/5)
How do you calculate BSA?
Image: How do you calculate BSA?
How do you calculate BMI?
Image: How do you calculate BMI?
How do you convert from inches to centimeters?
1 inch = 2.54 centimeters
How do you convert from pounds to kilograms?
2.2 pounds = 1 kg
IBW for men equation
50.0 kg + 2.3 kg per inch over 5 feet.
IBW for women equation
45.5 kg + 2.3 kg per inch over 5 feet.
What is the equation for adjusted body weight
Adjusted body weight = 0.4 (actual body weight - ideal body weight) + ideal body weight
The Waxman-Hat Act required generic drugs to prove which of the following?

A) proof of interchangability
B) proof of bioequivalence
C) proof of therapeutic equivalence
B) proof of bioequivalence
When should you use TBW for calculating CrCl?
If the patient is underweight (IBW < TBW)
When should you use Adjusted BW for calculating CrCl?when their TBW is 30% their IBWWhat is the Cockcroft-Gault equation?What are the T score cutoffs for osteopenia/osteoporosis/etc?Osteopenia: -1 to -2.5 Osteoporosis - 2.5 and below Severe osteoporosis: - 2.5 and below plus 1 or more fragility fracture1 oz = ____ mL30 mL1 cup = ___ oz = ___ mL8 oz = 240 mL1 oz = ___ g28.41 gallon = __ mL3,840 mLs (also equals 4 quarts = 16 cups = 128 oz)For K+ and Na+, 1 mEq = 1 ______mmol Also true for ammonium chlorideFor Ca+ 1 mEq = ___ mmol0.5 mmol Also true for ferrous sulfate and magnesium sulfateHow do you calculate the number of mEqs in something?mEQs = mg/MWHow do you calculate the osmolarity/L?osmolarity/L = (weight in grams/MW) * number of particles * 1000With regards to osmolarity calculations... How many particles are there in Dextrose?1With regards to osmolarity calculations... How many particles are there in Mannitol?1With regards to osmolarity calculations... How many particles are there in potassium chloride?2With regards to osmolarity calculations... How many particles are there in sodium chloride?2With regards to osmolarity calculations... How many particles are there in sodium acetate?2With regards to osmolarity calculations... How many particles are there in Calcium chloride?3With regards to osmolarity calculations... How many particles are there in sodium citrate?41 meter = ____ cm100 cmWhat is the calculation for corrected Phenytoin levels?Corrected Phenytoin = Measured Phenytoin / [(0.2 * albumin) + 0.1]How many mg are in 1 grain ?65 mgWhat is the recommended weight based dosing for acetominophen in a child under 12 years old?10-15 mg/kgTo convert aminophylline to theophylline, you must _____________ the dose by 0.8multiplyTo convert theophylline to aminophylline, you must _____________ the dose by 0.8divideTo convert from percent strength to PPM you must...Most the decimal to the right *4 spaces*To convert from PPM to percent strength you must...Most the decimal to the left *4 spaces*What is the formula for standard gravity (SG)?SG = g/mLHow do you calculated the amount of mols or mmols in a substance?mols = g/MW mmols = mg/MWTrue or false... With regards to pharmacy calculations, the terms calories and kcals are interchangabletrue! While calories are actually much smaller than kcals, it looks like culture has gradually stripped its metric gloryIn TPNs, dextrose provides carbohydrates and provides approximately ___ kcals/gram3.4 kcals/gramIn TPNs, glycerol provides carbohydrates and provides approximately ___ kcals/gram4.3 kcals/gram May be used as an alternative to dextrose in patients with impaired insulin secretion.What are the kcal/mL of the following IV fat emulsions (IVFE) 10%: 20%: 30%:10%: 1.1 kcal/mL 20%: 2 kcal/mL 30%: 3 kcal/mLHow much kcal is present in 1 gram of amino acids?4 kcal/gHow do you calculate the daily fluid needs of someone over 20kg in weight?1500 mL + [20mL * (weight in kg - 20)]What are the daily protein requirements for a hospitalized or malnourished patient?1.2-2g/kg/dayWhat are the daily protein requirements for an ambulatory or non-hospitalized patient?0.8-1g/kg/dayThis substance is considered a glidant/lubricant and may be used in non-sterile compounding to improve the flowability of a powder. A) Glycerin B) Magnesium Stearate C) Sodium lauryl sulfate D) GlycerolB) Magnesium StearateThis substance is considered a surfactant and may be used in non-sterile compounding to neutralize the static charge of a powder to prevent the particles from flowing away. A) Glycerin B) Magnesium Stearate C) Sodium lauryl sulfate D) GlycerolC) Sodium lauryl sulfateThis substance is considered a levigating agent and may be used in non-sterile compounding to aid in comminution. A) Glycerin B) Magnesium Stearate C) Sodium lauryl sulfate D) GlycerolA) GlycerinThis substance is considered a plasticizer and may be used in non-sterile compounding to make the capsules less brittle and more flexible. A) Glycerin B) Magnesium Stearate C) Sodium lauryl sulfate D) GlycerolD) Glycerol May also use sorbitolGlycerl monosterate, pectin, PEG, sodium lauryl sulfate, and sortiban esters may *all* be used as... A) Emulsifiers B) Plastifiers C) Preservatives D) Surfactants E) GlidantsA) Emulsifiers Some may have additional uses. See other questions on non-sterile compounding substances included.Colloidal sillica, cornstarch and talc may *all* be used as... A) Emulsifiers B) Plastifiers C) Preservatives D) Surfactants E) GlidantsE) GlidantsChlorhexedine, EDTA, sodium benzoate, benzalkonium chloride, thimerosal, and benzoic acid may *all* be used as... A) Emulsifiers B) Plastifiers C) Preservatives D) Surfactants E) GlidantsC) PreservativesThis/these excipient(s) would be considered adsorbents. A) Magnesium stearate B) Magenesium oxide/carbonate, kaolin C) Simethicone D) Ascorbic acid E) Shellac, gelatin, glutenA) Magnesium stearateThis/these excipient(s) would be considered antioxidants. A) Magnesium stearate B) Magenesium oxide/carbonate, kaolin C) Simethicone D) Ascorbic acid E) Shellac, gelatin, glutenD) Ascorbic acidThis/these excipient(s) would be considered anti-foaming agents. A) Magnesium stearate B) Magenesium oxide/carbonate, kaolin C) Simethicone D) Ascorbic acid E) Shellac, gelatin, glutenC) SimethiconeThis/these excipient(s) would be considered anti-adherent agents (to prevent the ingredients from sticking to things during production A) Magnesium stearate B) Magenesium oxide/carbonate, kaolin C) Simethicone D) Ascorbic acid E) Shellac, gelatin, glutenB) Magenesium oxide/carbonate, kaolinThis/these excipient(s) would be considered coating agents (to prevent degradation from light, oxygen, moisture, etc) A) Magnesium stearate B) Magenesium oxide/carbonate, kaolin C) Simethicone D) Ascorbic acid E) Shellac, gelatin, glutenE) Shellac, gelatin, glutenThis/these excipient(s) would be considered buffer agents to maintain an acceptable pH for the product. A) Potassium phosphate, sodium acetate/citrate B) FD&C #3, Yellow #6 C) Starches, calcium salts, lactose, cellulose, mannitol, sorbitol D) Petroleum jelly, vaseline E) Algenic acid, polacrillin potassiumA) Potassium phosphate, sodium acetate/citrateThis/these excipient(s) would be considered diluents/filler agents A) Potassium phosphate, sodium acetate/citrate B) FD&C #3, Yellow #6 C) Starches, calcium salts, lactose, cellulose, mannitol, sorbitol D) Petroleum jelly, vaseline E) Algenic acid, polacrillin potassiumC) Starches, calcium salts, lactose, cellulose, mannitol, sorbitolThis/these excipient(s) would be considered emollient agents A) Potassium phosphate, sodium acetate/citrate B) FD&C #3, Yellow #6 C) Starches, calcium salts, lactose, cellulose, mannitol, sorbitol D) Petroleum jelly, vaseline E) Algenic acid, polacrillin potassiumD) Petroleum jelly, vaselineRecommended compounding ingredients are listed on which of these resources? A) Orange book B) Purple book C) Martindales D) USP-NFD) USP-NFThis/these excipient(s) would be considered disintegrant agents A) Potassium phosphate, sodium acetate/citrate B) FD&C #3, Yellow #6 C) Starches, calcium salts, lactose, cellulose, mannitol, sorbitol D) Petroleum jelly, vaseline E) Algenic acid, polacrillin potassiumE) Algenic acid, polacrillin potassium starches, cellulose, and compressible sugar also have these properties.This/these excipient(s) would be considered coloring agents A) Potassium phosphate, sodium acetate/citrate B) FD&C #3, Yellow #6 C) Starches, calcium salts, lactose, cellulose, mannitol, sorbitol D) Petroleum jelly, vaseline E) Algenic acid, polacrillin potassiumB) FD&C #3, Yellow #6Which of the following ISO classifications will have the least number of particles present? A) 5 B) 6 C) 7 D) 8A) 5 Class 5 ISO would be a hood or isolator. Class 7 would be a negative pressureUSP guidelines for assigning BUD recommend a 48 hour BUD for this type of compounded product if stored at room temperature. A) Low B) Medium C) High D) Immediate UseA) LowUSP guidelines for assigning BUD recommend a 1 hour BUD for this type of compounded product if stored at room temperature. A) Low B) Medium C) High D) Immediate UseD) Immediate UseUSP guidelines for assigning BUD recommend a 30 hour BUD for this type of compounded product if stored at room temperature. A) Low B) Medium C) High D) Immediate UseB) MediumUSP guidelines for assigning BUD recommend a 24 hour BUD for this type of compounded product if stored at room temperature. A) Low B) Medium C) High D) Immediate UseC) HighUSP guidelines for assigning BUD recommend a 9 day BUD for this type of compounded product if refrigerated. A) Low B) Medium C) High D) All of the above E) A and B onlyB) MediumUSP guidelines for assigning BUD recommend a 3 day BUD for this type of compounded product if refrigerated. A) Low B) Medium C) High D) All of the above E) A and B onlyC) HighUSP guidelines for assigning BUD recommend a 14 day BUD for this type of compounded product if refrigerated. A) Low B) Medium C) High D) All of the above E) A and B onlyA) LowUSP guidelines for assigning BUD recommend a 45 day BUD for this type of compounded product if frozen. A) Low B) Medium C) High D) All of the above E) A and B onlyD) All of the aboveQuinolones and metronidazole work through... A) Folic Acid Synthesis B) Cell Wall Inhibitor C) DNA/RNA Inhibitor D) Cell Membrane Inhibitor E) Protein Synthesis InhibitorC) DNA/RNA InhibitorTMP works through... A) Folic Acid Synthesis B) Cell Wall Inhibitor C) DNA/RNA Inhibitor D) Cell Membrane Inhibitor E) Protein Synthesis InhibitorA) Folic Acid SynthesisBeta-lactams, cephalosporins, aztreoname, and vancomycin work through... A) Folic Acid Synthesis B) Cell Wall Inhibitor C) DNA/RNA Inhibitor D) Cell Membrane Inhibitor E) Protein Synthesis InhibitorB) Cell Wall InhibitorDaptomycin and Colistimethalate (polymyxin) work through... A) Folic Acid Synthesis B) Cell Wall Inhibitor C) DNA/RNA Inhibitor D) Cell Membrane Inhibitor E) Protein Synthesis InhibitorD) Cell Membrane InhibitorAminoglycosides, macrolides, tetracyclines, linezolid and clindamycin work through... A) Folic Acid Synthesis B) Cell Wall Inhibitor C) DNA/RNA Inhibitor D) Cell Membrane Inhibitor E) Protein Synthesis InhibitorE) Protein Synthesis InhibitorAminoglycosides, quinolones, and daptomycin display... A) Time-dependent effects B) Concentration-dependent effects C) AUC/MIC effectsB) Concentration-dependent effectsVancomycin, macrolides, tetracyclines, and colistimethate display... A) Time-dependent effects B) Concentration-dependent effects C) AUC/MIC effectsC) AUC/MIC effectsBeta-lactams (penicillins, cephalosporins, carbapenems) display... A) Time-dependent effects B) Concentration-dependent effects C) AUC/MIC effectsA) Time-dependent effectsProbenecid can have what effect on beta-lactam levels? A) Increase B) DecreaseA) Increase Interferes with excretion and thus increases blood levelsAs a general rule, penicillins may have what effect on a patients INR if taken alongside warfarin? A) Increase B) DecreaseA) IncreaseCephalosporins bioavailability may ____________ when taken with medications that can reduce stomach acid.decrease Should separate 2 hours from tums and avoid H2RAs and PPIs while on cephalosporinsWhich of the following cephalosporins is active against MRSA? A) Cefazolin B) Cephalexin C) Cefdinir D) Ceftriaxone E) Cefepime F) CeftarolineF) CeftarolineWhich of the following cephalosporins is active against pseudomonas? A) Cefazolin B) Cephalexin C) Cefdinir D) Ceftriaxone E) Cefepime F) CeftarolineE) Cefepime Also Ceftazidime/Avibactam and Ceftolozane/TazobactamThis carbapenem is notable for having no pseudomonas coverage. A) Doripenem B) Imipenem/Cilastatin C) Meropenem D) ErtapenemD) ErtapenemCarbapenems may have what effect on valproic acid levels when taken together? A) Increase VPA levels B) Decrease VPA levels C) No effectB) Decrease VPA levelsWhat is the IV:PO ratio for Ciprofloxacin?1:1.25 so 1 mg IV = 1.25 mg POWhich of the following is an example of type I error? A) Accepting the null hypothesis when the null hypothesis is false B) Rejecting the null hypothesis when the null hypothesis is trueB) Rejecting the null hypothesis when the null hypothesis is true Means you're saying there's a difference when there is notWhich of the following is an example of type II error? A) Accepting the null hypothesis when the null hypothesis is false B) Rejecting the null hypothesis when the null hypothesis is trueA) accepting the null hypothesis when the null hypothesis is false.What class of HIV medications is most likely to cause pancreatitis? A) NRTIs B) NNRTIs C) PIsA) NRTIs Some NRTIs can cause pancreatitis, and the majority are cleared renallyWhat class of HIV medications is most likely to cause metabolic issues (such as hyperlipidemia, glucose intolerance, and fat maldistribtuion) A) NRTIs B) NNRTIs C) PIsC) PIsWhat is the formula for corrected calcium?