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Psych drugs

Terms in this set (48)

Fluoxetine
longest half life
Duloxetine
effective for physical pain/somatization
Venlafaxine
Side effect is increased BP, indicated for ADHD
Bupropion
No sexual problems or weight gain, indicated for smoking cessation and ADHD, increased chance of seizures ( DO NOT USE IN PT'S WITH EATING D/O OR SEIZURES)
Trazadone
insomnia treatment, priapism
Amitriptyline
chronic pain and migraine
Imipramine
2nd line for enuresis,
Clomipramine
approved for OCD but chance of seizures
Doxepin
sedating (helps with insomina), strong anti-histamine (helps pruritis)
Mirtazapine
H1 side effects (weight and sedations) increased with decrease in dose
Ziprasidone
metabolic syndrome LESS likely
Ariprprazole
metabolic syndrome LESS likely
Olanzapine
Risk of metabolic syndrome
Clozapine
most effective anti-psychotic and decrease suicide but third line b.c of possible side effect of agranulocytosis, also risk of seizures and metabolic syndrome
Lithium carbonate
kidney excretion, decreases suicide
valproic acid
excreted thru liver
Lamotrigine
side effect-Stevens Johnson rash
Carbamazepine
induced it own metabolism, OCP less effective
benzos safe for live (3)
lorazepam, oxazepam, temazepam
Lorazepam
PO and IM, safe for liver
Disulfiram
competitively inhibits aldehyde dehydrogenase, aversive (sick after drinking)
Naltrexone
opioid antagonist, experience of drinking not as good, less cravings
Naloxone
prevents/reverses effects on opioids, used to treat heroin OD
Acamprodate
Acts on GABA/NMDA, reduces craving, no effect on drinking experience
Methadone
opioid used a maintenance therapy to treat heroin dependence at Methadone clinic
Buprenorphine
synthetic opioid that is booth a partial agonist and antagonist, used sublingually as maintenance therapy to treat heroin dependance
Suboxone
Buprenorphine + Naloxone which prevents misuse of this substance
Pregnancy category D: Paroxetine
Pulmonary Hypertension
Pregnancy category D: Lithium
Ebstein's Anomaly
Pregnancy category D: VPA and carbamazepine
neural tube defects
Pregnancy category D: Benzodiazepine
Cleft lip/palate
SSRI: treatment fo (2)
depression and anxiety
SSRI: common side effects
GI, headaches, sexual, anxiety, risk of mania
SSRI: lethal side effects
serotonin syndrome, black box for inc in suicidality for pts <25
MAOI: Indications (2)
refractory depression and atypical depression
MAOI: common side effects
orthostatic hypotension, sedation, wt gain, sexual dysfunction
MAOI: lethal side effects
hypertensive crisis
TCA's: Indications (1)
refractory depression
TCA: common side effects
anticholinergic-dry mouth, constipation, urinary retention blurry vision; adrenergic-orthostatic hypotension, dizziness, reflex tachycardia; histamine-sedation, wt gain
Mood stabilizers: indications (2)
bipolar and schizoaffective bipolar type
Mood stabilizers: efficacy
lamotrigine is maintenance only, lithium and valproic acid
Antipsychotics: indications (1)
psychosis (atypicals are first line)
Antipsychotics: side effects, typical vs. atypical vs. low potency typical vs. high potency typical
high potency-EPS, dystoinia, akathisia; low potency typical-antihistamine, antiadrenergic, anticholinergic; typical-TD, hyperprolactinemia, NMS; atypicals-metabolic syndrome
Antipsychotics: lethal side effects
NMS, akathesia (inc suicide risk), metabolic syndrome, rarely dystonia (if airway ms are involved)
Benzos: indications (2)
alcohol withdrawal, anxiety but sue with SSRI unless symptoms are rare
Benzos: common side effects
short term memory impairment, interactions with alcohol
Benzos: lethal side effects
decrease respiration, lethal in OD with alcohol
Lamotrigine: uses
BPAD, BPAD depression, NOT ACUTE MANIA
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