"Ornithosis"....inhales of dried shit from parrots....bite of bird and direct contact with a patient....1-3 week incubation....Microscopy: alveolar damage with INTRACYTOPLASMIC BODIES..
**can cause lethal disease of focal necroses and mononuclear infiltrate
70% of infected women have it and asymptomatic....MOST COMMON STD IN THE USA...men get prostatitis and epididymitis...women et cervicitis and salpingitis and PID
What is chlamydia inclusion conjunctivitis?
chlamudia inclusions in EXUDATE and lymphocytic infiltration in tissue.
get it from mom or from swimming pools.
C. trachomatis ABC
leading global cause of blindness via scarring....TRACHOMA. transmission: flies, DC, fomites. MORPHOLOGY: suppuration- deeper infiltration with lymphocytes and plasma. LYMPHOID cell follicles....ulcerration and vascular invasions, fibroblast overgrowth scarring.
R. prowazeki...man louse man....poor sanitation. Contaminated louse shit penetrate the skin abrasions
What is the triad for this disease?
fever, HA, maculopapular rash apathy stupor, coma.....
typhus nodule : small vessel lesion in brain with infiltration
What is Sporadic Typhus?
Brill-Zinsser disease....reinfection of dormant Rick in the spleen
What is the diagnosis?
Weil felix reax, immunoflourescene and antibodies
What is Rocky mountain spotted fever?
R. rickettsii.....blood sucking ticks of Dermacentor's salivary glands....TICKS ARE BOTH THE VECTORS AND THE RESERVOIR
Clinical manifest of RMSF?
rash of palms and soles....maculopapular and becomes purpuric...spreads centripetally....ESCHAR at the bite site... necrotic skin foci. death from shock
Microscopy/diagnosis of of RMSF?
endothelial cells causing arteritis and thrombosis causing necrosis. IMMUNOFLOURESCENCE
Trench fever....vector is body lice....homeless alcoholics!.....5 -day Quintana fever!....high fever headache, back pain, shin pain, and a FLEETING RASH
Cat Scratch Disease
B. henselae..inoculation lymphoreticulosis or subacute regional lymphadenitis. (intracellular gram negative bacteria).....lymphadenopathy from arms, neck, jaw, groin, ear.Vesicle or ERYTHEMATOUS papule at site of infection
Microscopy of CSD
LN with histiocytic granulomas, central necrosis/neutrophilic infiltrations....symptoms: malaise, decreased apetite, aches. Granulmoatous conjunctivits with swelling of LN near ear
Orientia tsutsugamushi....mite born dz. vector: tombiculid mite (chigger)......BLACK ESCHAR!
Wbat is Mycoplasma?
aka Eaton Agent. pleomorphic bacteria that lack cell wall (PPLO pneumonia and pleuritis).....parasitize MEMBRANE CELLS binding to epithelial lining of GI/RESP tract
purulent non gonococcal urethritis causing PID....may produce chorioamniotis
aerosol/droplet.....most in close quaretes (dorms, boarding school).....disrupt cilia and damage resp epithelium......they produce COLD AGGLUTININS AND COMPLEMENT FIXING ANTIBODIES......may cause false-positive serologic tests for syphilis
Microscopy of Mycoplasma pneumonia
interstitial pneumonia, alveolar air spaces empty, thick alveolar walls (intra-septal inflammation with mononuclear infiltrate).
Clinical Mycoplasma pneumo
walking pneumonia....low mortality. sore throat and unproductive cough...COMPLICATIONS THOOOOO.....myocarditis, miringitis, SJS (Steven Johnson Syndrome- periorificial ecto dermitis formed by ulcerated papule)
Microbial Diseases of the Cardiovascular and Lymphatic Systems Chapter 2380 terms