PB 44

Term
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Neural Tube closure complete at what gestation
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Terms in this set (10)
Neural Tube closure complete at what gestation
4 wks post conception 6 wks gestation
2 categories of neural tube defects
cranial: skull, scalp, and brain tissue
spinal: spina bifida (spinal cord meninges, and vertebrae)
Most NTDs affecting the spine are associated with?
ventriculomegaly
Enlargement of cerebral ventricles
result of Arnold Chiari Malformation type II
Types of Cranial NTD
Anenecephaly (failure of fusion of cephalic portion of neural tube folds)
Exencephaly (failure of scalp and skull formation)
Encephalocele (failure of skull formation)
Iniencecphaly (defect cervical and upper thoracic vertebrae)
Spinal NTDs
Spina bifida (failure of caudal portion of neural tube)
Meningocele (failure of fusion of caudal portion of neural tube meninges exposed)
Meningomylocele (failure of caudal portion to fuse meninges and neural tube exposed)
Myeloschisis (failure of caudal fusion flattened mass of neural tube exposed)
Holorachischisis (failure of vertebral arches to fuse entre spinal cord exposed)
Craniorachischisis (co exiting anencephaly and rachischisis)
Degree of handicap for spina bifida most accurately predicted by?
Level of lesion
the higher the level the more deficits seen
At least one third of NTD have an allergy to what?
Latex
In the absence of intracranial pressure there is no correlation bt. _________ and ___________
ventricular size and intellectual performance
Etiology of NTD
Combo of genetic and environmental influences
Homozygous for what gene mutation can be overcome with Folate supplementation
MTHFR