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Micro (someone elses quizlet)
Terms in this set (56)
E - are an alternative to the use of chemotherapy involving microbial antagonism
A. involve microbial antagonism.
B. are an alternative to the use of chemotherapy.
C. involve the use of extracts from microorganisms.
D. is a term for resistance to antibiotics.
E. are an alternative to the use of chemotherapy involving microbial antagonism.
B - porins
Alterations in the structure of which of the following are an important aspect of Gram-negative bacterial resistance to antimicrobial drugs?
D. cytoplasmic membrane
E - waksman
Which scientist coined the term antibiotic?
A - preventing the cross-linkage of NAM subunits.
Most drugs that inhibit the synthesis of the cell wall act by
A. preventing the cross-linkage of NAM subunits.
B. blocking the secretion of cell wall molecules from the cytoplasm.
C. preventing the formation of alanine-alanine bridges.
D. disrupting the formation of the mycolic acid layer of the cell wall.
E. preventing the formation of ?-lactamases.
A - quinolones
Which of the following drugs inhibits nucleic acid synthesis specifically in prokaryotes?
C - thier activity against cell walls
Which of the following is NOT a criterion by which all antimicrobial agents can be evaluated?
A. their spectrum of action
B. their efficacy
C. their activity against cell walls
D. their route of administration
E. their safety
E - both fluconazole & turbinafine
Which of the following works by inhibiting ergosterol synthesis?
C. amphotericin B
E. both fluconazole and turbinafine
C - Resistant cells grow more efficiently & quickly than susceptible cells
Which of the following statements concerning development of antibiotic resistance is FALSE?
A. It is often mediated by R-plasmids.
B. Resistant cells are normally in the minority in a bacterial population.
C. Resistant cells grow more efficiently and quickly than susceptible cells.
D. New resistance genes can be gained through transformation, transduction, or conjugation.
E. Resistance can occur through mutation of existing bacterial genes.
D - tetracyclines
Which of the following groups of drugs can become incorporated into the bones and teeth of a fetus?
B - inactivation of the drug
B-lactamase production is an example of which of the following types of resistance?
A. alteration of the target of the drug
B. inactivation of the drug
C. change in the permeability of the drug
D. overproduction of an enzyme in a key metabolic pathway
E. removal of the drug via a pump
B - lack of turbidity
Which of the following is a measurement associated with the broth dilution test?
A. the zone of inhibition
B. lack of turbidity
C. cell lysis
D. lack of turbidity and zone of inhibition
E. presence of turbidity and cell lysis
B - inhibiting protein synthesis
Most broad-spectrum antibiotics act by
A. inhibiting the synthesis of the cell wall.
B. inhibiting protein synthesis.
C. inhibiting nucleic acid synthesis.
D. inhibiting metabolic pathways.
E. disrupting the cytoplasmic membrane.
E - streptomyces
A large percentage of antibiotics and semisynthetic drugs are produced by members of the genus
D - both susceptibility and MIC
The Etest determines which of the following?
D. both susceptibility and MIC
E. both MBC and MIC
E - selective toxicity takes advantage of structural and/or metabolic differences between host and pathogen
Which of the following statements is true of selective toxicity?
A. Selective toxicity takes advantage of structural differences between host and pathogen.
B. To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen.
C. Selective toxicity takes advantage of metabolic differences between host and pathogen.
D. Antimicrobial agents must target structural differences between host and pathogen and be more toxic to the patient than the pathogen.
E. Selective toxicity takes advantage of structural and/or metabolic differences between host and pathogen.
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