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Chapter 23--Microbial Diseases of the Cardiovascular and Lymphatic Systems
Terms in this set (59)
How does Microbial Diseases of Cardiovascular and lymphatic systems occurs?
Blood: Transports nutrients to and wastes from cells.
WBCs: Defend against infection.
Lymphatics: Transport interstitial fluid to blood.
Lymph nodes: Contain fixed macrophages.
What is Septicemia?
Bacteria growing in the blood
What happen if Severe sepsis occurs?
Severe sepsis: Decrease in blood pressure
What will happen if suffer with septic shock?
Low blood pressure cannot be controlled
Septic shock affect?
Kidney that leads to renal failure
What is Lymphangitis?
Inflammation of lymphs or Blood poisoning.The most common cause of lymphangitis in humans is Streptococcus pyogenes (Group A strep
What are 2 causes of agent of sepsis?
Endotoxins caused blood pressure decrease.
Antibiotics can worsen condition by killing bacteria.
Gram-positive sepsis- Exotoxins
What is the process of Gram neg sepsis
Through process of Endotoxins
What is the process of Gram pos
Through the process of Exotoxins
what is the first disease of sepsis?
Puerperal sepsis (childbirth fever)
Cause of agent of puerperal sepsis?
How does puerperal sepsis transmit?
Transmitted to mother during childbirth by attending physicians and midwives. improper sanitizing.
Symptoms of puerperal sepsis?
Addominal pain and eventually will leads to sepsis and all same symptoms as sepsis.
What are the two main types of bacterial endocarditis?
Subacute bacterial endocarditis:
Alpha-hemolytic streptococci from mouth
Acute bacterial endocarditis:
Staphylococcus aureus from mouth
Symptoms of endocarditis?
Fatigue, Chest pain, heart murmur and difficulties breathing. Heart valve eating away...
symptoms of sepsis?
Fever followed by respiratory rate difficulties breathing , increase heart rate and also showing signs symptoms of encephalitis
Rheumatic fever is an inflammatory disease that may develop after an infection with Streptococcus bacteria (such as strep throat or scarlet fever). The disease can affect the heart, joints, skin, and brain.
Autoimmune complication for Rheumatic fever?
Streptococcus pyogenes infections
What are symptoms of rheumatic fever?
High fever lead to heart failure
Nodule deformation leads to calcifications.
Transmission of rheumatic fever?
By respiratory routes and fomite or normal microbiota that starts with streptoccocus.
What is Tularemia?
Tularemia also known as Pahvant Valley plague
 rabbit fever
 deer by deer flies fever
How does tularemia transmit?
Transmitted from rabbits and deer by deer flies.
Bacteria reproduce in phagocytes.
Cause of agent for tularemia?
High fever, swollen limb nodes that leads to sepsis.
What is Brucellosis and what is also known to?
Brucellosis is an infectious disease that occurs from contact with animals carrying Brucella bacteria.
What are symptoms of Brucellosis?
Undulating fever that spikes to 40°C each evening on and off that may lead to sepsis.
What is mode of transmission of brucellosis?
Transmitted via milk from infected animals or contact with infected animals.
Cause of agent for Brucellosis?
What is anthrax?
Anthrax is an infectious disease due to a type of bacteria called Bacillus anthracis. Infection in humans most often involves the skin, gastrointestinal tract, or lungs (Inhalation)
3 forms of anthrax
Endospores enter through minor cut
Gastrointestinal anthrax- much higher risk than cutaneous
Ingestion of undercooked food contaminated food
Inhalation of endospores.
100% mortality- very fatal
symptoms of anthrax?
Flu like symptoms lead to death, association with cattle.
What is gangrene?
Gangrene is the death of tissue in part of the body.
What is gas gangrene?
?Gas gangrene is a potentially deadly form of tissue death (gangrene).Gas gangrene causes very painful swelling. The skin turns pale to brownish-red. If you press on the swollen area with your fingers, you may feel gas as a crackly sensation. The edges of the infected area grow so quickly that changes can be seen over a few minutes. The area may be completely destroyed
What cause of agent of gas gangrene
Clostridium perfringens,endospore-forming, grows in necrotic tissue
Treatment for gas gangrene?
Treatment includes surgical removal of necrotic tissue and/or hyperbaric chamber.
symptoms of gas gangrene?
Fever may lead to sepsis, and enlargement of area due to gas production of CO2
Mouth flora of Animals vs Human?
Human bite injuries are often believed to be more serious than animal bite injuries. One reason for this distinction might be a species difference in the microbial mouth flora. In order to compare this possibility, we cultured the mouths of humans, dogs, and cats. Human oral flora contained the smallest number of bacteria followed by dog and cat oral flora, respectively. Veillonella parvula was cultured from all humans and was also found in dog and cat mouths, but less frequently. V parvula is not usually considered a virulent organism but occasionally may become a pathogen and should not be overlooked especially following human bite injury.
What is Bartonella hensellae?
is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis
What is the causative of agent of Bartonella hensellae?
causative agent of cat-scratch disease (Bartonellosis) which, as the name suggests, occurs after a cat bite or scratch
symptoms of bartonella hensellae?
The disease is characterized by lymphadenopathy (swelling of the lymph nodes) and fever.
What is plague?
Plague is caused by the bacteria Yersinia pestis. Rodents, such as rats, ground squirrels and prairie dogs that carry the disease. It is spread by their fleas. Also known a "Black death"
mode of transmissions of plague
People can get the plague when they are bitten by a flea that carries the plague bacteria from an infected rodent. In rare cases, you may get the disease when handling an infected animal. most often fleas transmission by a prairie dogs.
A plague lung infection called pneumonic plague can spread from human to human. When someone with pneumonic plague coughs, tiny droplets carrying the bacteria move through the air. Anyone who breathes in these particles may catch the disease. An epidemic may be started this way.
What are the three most common forms of plague?
Bubonic plague -- Bacterial growth in blood and the lymph nodes. this is the initial symptoms.
Pneumonic plague -- an infection of the lungs
Septicemic plague -- an infection of the blood or septic shock
Causative agents of plague?
What is cystomegalovirus Infections?
It's a viral disease that replicates in blood.cytomegalovirus (from the Greek cyto-, "cell", and -megalo-, "large") is a viral genus of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as CMV
Mode of transmission of cytomegalovirus
Transmitted sexually, by blood, or by transplanted tissue. Transmitted across the placenta; may cause mental retardation. 80 to 90 percent of people are infected by this disease but developed antibodies and it's asimptomatic symptoms who has it.
Give example of Viral Hemorrhagic fevers
Yellow fever- High fever, night sweats and jaundice of skin transmitted by mosquito bites.
Ebola fever- bleeding on skin, nose, ears, eyes- very fast acting disease destroy capillary and organs transmission through blood as direct contact
Hantavirus pulmonary syndrome- very fast acting- inhalation of virus from fecal and urine from mice cause respiratory failures
Dengue- also know as breakbone fever, very painful in joints associated with high feve. transmitted by mosquito bites
What is toxoplasmosis?
Toxoplasmosis is not virals disease it is a parasitic disease caused by the protozoan Toxoplasma gondii.
Mode transmissions of toxoplasmosis?
The parasite spreads by the ingestion of infected meat (uncooked food) or the feces of an infected cat, or by vertical transmission from mother to fetus. altering certain human behavior such as owner can be a loner and tendency of high risk of driving. and hoarding more cats.
causative agent of toxoplasma?
What is symptoms of malaria?
Malaria is a parasitic disease that involves high fevers, shaking chills,sweating flu-like symptoms, and anemia, lock of appetite, very fatigue
What is malaria?
Malaria is caused by a parasite that is passed from one human to another by the bite of infected Anopheles mosquitoes. After infection, the parasites (called sporozoites) travel through the bloodstream to the liver, where they mature and release another form, the merozoites. The parasites enter the bloodstream and infect red blood cells might cause internal clotting. clotthing can form in kidney that form renal failures.
Causative agent of malaria?
Falciparum ( worse malaria to get, fast acting )malaria
Plasmodium vivax (Protozoan)
what is Leishmaniasis?
Very difficult to treat , cause multi organ failure, protozoan disease, is a disease spread by the bite of the female sandfly. that only come out during night and calm weather not windy.
Causative agent of Leishmaniasis
Geographic distributions of Leishmaniasis
Asia, Africa, Southest Asia
What is Schistosomiais?
parasytic disease of worms, worms get large in different organ that results in organ failure.. Tissue damage (granulomas) in response to eggs lodging in tissues. found in normal water if there is reservoirs such as snails
What is swimmer's itch?
Swimmer's itch, also known as lake itch, duck itch, cercarial dermatitis, and Schistosome cercarial dermatitis.
How does schistosomiasis disease work in the system?
when contracted with this disease in mesentery of digestive system male and female mates and hatch eggs. may take years to develops, diagnos through stool samples to looks for some eggs from parasites.
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