Terms in this set (9)
What is the BRAND name of this drug?
What is the drug CLASS of Procainamide Hydrochloride?
What is/are the proper ADULT dose/route(s) of Procainamide Hydrochloride?
Recurrent V. Fib/pulseless V. Tach: 20 mg/min slow IV infusion (maximum dose: 17 mg/kg). In urgent situation, up to 50 mg/min may be administered (maximum dose: 17 mg/kg). Other indications: 20 mg/min slow IV infusion until any one of the following occurs: Dysrhythmia suppression, hypotension, QRS widens by >50% of its pretreatment width, or total dose of 17 mg/kg has been given. Maintenance infusion: 1-4 mg/min (diluted in D 5 W or NS). Reduce dose in presence of renal insufficiency.
What is/are the proper PEDIATRIC dose/route(s) of Procainamide Hydrochloride?
Loading dose 15 mg/kg IV/IO over 30-60 mins.
How does Procainamide Hydrochloride work on the body? (I.E.- Mechanism of Action)?
Suppresses phase 4 depolarization in normal ventricular muscle and Purkinje fibers, reducing ectopic pacemaker's automaticity; suppresses intraventricular conduction.
What are the INDICATIONS for administering Procainamide Hydrochloride?
Stable monomorphic V. Tach. w/ normal QT interval, reentry SVT uncontrolled by vagal maneuvers and adenosine, stable wide complex tachycardia of unknown origin, atrial fibrillation with rapid ventricular rate in pt's with Wolff-Parkinson-White syndrome.
What are the CONTRAINDICATIONS for administering Procainamide Hydrochloride?
Torsades de pointes, 2nd and 3rd degree heart atrioventricular block (without functioning artificial pacemaker), preexisting QT prolongation, digitalis toxicity, tricyclic antidepressant overdose.
What are the potential SIDE EFFECTS/ADVERSE REACTIONS of Procainamide Hydrochloride?
Confusion, seizures, hypotension, bradycardia, reflex tachycardia, ventricular dysrhythmias, AV blocks, asystole, widening of PR, QRS, and Q-T intervals, N/V.
When would SPECIAL CONSIDERATIONS be taken?
Pregnancy safety: Cat. C. Potent vasodilation and negative inotropic effects. Hypotension may occur with rapid infusion. Administer cautiously to patients with cardiac, hepatic, or renal insufficiency. Administer cautiously to pt's with asthma or digitalis-induced dysrhythmias.
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