How does hypothyroidism present clinically?
weakness, fatigue, arthralagias, myalgias, HA, depression, cold intolerance, weight gain, constipation, menorrhagia, dry skin, coarse hair, brittle nails, carpal tunnel syndrome, delayed DTR, diastolic HTN, hyperlipidemia
slow speech, hoarseness, loss of outer third of eyebrows, myxedema (inc glycosominoglycans), periorbital puffiness, bradycardia, pleural, pericardial and peritoneal effusions, atherosclerosis.
hypothermia, hypotension, hypoventilation, AMS
possible hyponatremia, hypoglycemia, anemia, inc LDL, dec HDL, and inc CK