BMB 400 Exam 1

Physical associations of proteins in replication fork are important for regulating activities of proteins that coordinate replication fork progression. Answer protein that regulates an activity of the DNA helicase

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Terms in this set (5)

Physical associations of proteins in replication fork are important for regulating activities of proteins that coordinate replication fork progression. Answer protein that regulates an activity of the DNA helicase

DNA pol III holoenzyme

Structure of DNA polymerase resembles a right hand shape that contains Thumb, Palm and Fingers domains. Describe a function of Palm domain of DNA polymerase.

having active sites of both DNA synthesis and exsonuclease

Which of the following statements correctly describes the role of telomerase in eukaryotic cells?

It synthesizes DNA using a RNA template

Translesion (TLS) DNA synthesis enables DNA replication to proceed across DNAdamage. In bacteria, DNA polymerases IV and V participate in the TLS DNA synthesis. Answer a right statement to describe about these polymerases

DNA polymerases IV and V are expressed only under the condition having a lot of damages on DNA

DNA double-strand break can be repaired by either the double-strand break (DSB)repair or the nonhomologous end joining (NHEJ) repair pathways. Answer a right statement explaining these repair pathways

NHEJ repair is observed more frequent in human, but in bacteria, DSB repair is more common pathway