How can we help?

You can also find more resources in our Help Center.

Immunoglobulins

STUDY
PLAY
IgM
attached to B cells/free in plasma; serves as an antigen receptor when bound to a B cell; 1st Ig released to plasma by plasma cells; agglutination agent; fixes complement
IgA
monomer found in plasma, dimer found in secretions (mucous, tears, saliva, HCL, milk); protects mucosal surfaces from pathogens
IgD
attached to B cell; activates B cells
IgG
most abundant antibody in plasma; main antibody of primary/secondary responses; crosses placenta; fixes complement
IgE
secreted by plasma cells in skin and mucosae; allergic response
IgM
pentamer
IgD, IgG, IgE
Y shaped monomers
IgA
monomer or dimer