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Micro One Liners - GI and Hepatitis
Terms in this set (75)
1. Causative agent of nausea, vomiting (onset < 6 hr) after eating cold cuts, or potato salad, or mayonnaise, or custards?
2. Rapid-onset food poisoning is mediated by what component of staphylococcus?
3. Tx of staphylococcal food poisoning?
4. Microbial cause of nausea and vomiting, +/- diarrhea (onset < 6 hr) after eating reheated rice?
dipicolinic acid core
5. Bacterial spores are resistant to heat due to what component?
6. Microbial cause of nausea, vomiting, watery diarrhea w/ rapid (6-12 hr) after eating reheated meat or gravy?
7. Most likely cause of persistent dyspepsia in a pt not receiving NSAIDs is
H. pylori colonization
8. Increased risk of gastric adenocarcinoma and MALT lymphoma
Presence of organism
9. Indications to treat H. pylori-associated PUD
PPI + clarith + amox
10. Standard first-line abx for PUD due to H. pylori is
11. Cause of acute onset of diarrhea with rice-water stools, vomiting, dehydration during travel to South America
A-B toxin causes ↑ cAMP
12. Pathophysiology of cholera is due to what mechanism?
thiosulfate-citrate-buffered sucrose (TCBS) agar
Cholera pathogen is isolated from stool by culture on selective medium called
14. The comma-shaped cholera organisms are microscopically similar to
Rehydration (tet in severity)
15. Tx of cholera involves
Enterotoxic E. coli
16. Secretory diarrhea, fever and vomiting during travel are caused by
17. Secretory diarrhea w/ fatty, foul-smelling stools in campers, hikers, also day-care outbreaks is caused by
18. Following ingestion of 15-25 cysts, excysted trophozoites adhere at brush border of enterocytes and contribute to malabsorption. TOW?
Stool antigen (+)
19. Dx of giardiasis is confirmed by
20. Giardiasis is specifically treated with
Cryptosporidium >> Cyclospora > Isospora
21. Protracted, secretory diarrhea w/ large fluid loss in AIDS is caused by (clue: acid-fast organisms)
E. coli O157:H7
22. Frank bloody diarrhea, after eating undercooked meats or drinking fruit drinks, is caused by prepared foods or water, contaminated w/
Shiga toxin (a cytotoxin)
23. Pathogenesis of hemorrhagic enterocolitis caused by E. coli involves
hemolytic uremic syndrome
24. Complication of hemorrhagic enterocolitis in children
25. Profuse diarrhea, fever, vomiting, and dehydration in infants is caused by
26. Mechanism of rotaviral diarrhea involves
27. Infantile watery diarrhea and fever are caused by
28. Outbreak of nausea, vomiting, fever in adults is caused by
29. Cause of nausea/vomiting, abdominal cramps, diarrhea +/- bloody 8-48h after eating eggs or poultry or peanut butter?
carrier (in bile ducts) state
30. Abx treatment in acute gastroenteritis due to Salmonella spp. is not warranted to avoid
31. Abx used only to treat septic phase of salmonella gastroenteritis is
32. Cause of fevers (>103°), headaches;macular rash on torso ("rose spots") abdominal pain and little diarrhea later; PE: bradycardia; hepatosplenomegaly (+/-) in a pt with hx of travel (to tropics)?
33. Cause of diarrhea w/ occult blood, abdominal cramping and fever, 2d after ingestion of poultry-contaminated salad
34. Abx to treat campylobacter enteritis with high fevers in pregnancy, and HIV is
35. Cause of dysentery-like illness with fever + abdominal cramps, tenesmus + blood & mucus in children?
36. Dysentery due to invasive Shigella flexneri or dysenteriae in elderly is treated with
37. Cause of dysentery-like illness (+/- pseudoappendicitis or pseudo-crohn syndrome) in the northern region after eating cheese
38. Cause of dysentery-like illness in a patient w/ hx of broad-spectrum abx use
A (enterotoxin) + B (cytotoxin).
39. Clostridium difficile-associated diarrhea (CDAD) is mediated by toxins
EIA for stool toxins A or B
40. Lab confirmation of CDAD does not require stool Cx, but is based on
Metronidazole (mild) or oral vancomycin (severe/relapse)
41. Besides rehydration and cessation of inciting meds, CDAD is treated with
Fecal-oral and/or contact w/ environmental spores
42. Health-care associated (nosocomial) spread of Clostridium difficile diarrhea and protracted outbreak is due to
43. Hx of abdominal pain, tenesmus, stools with mucus + blood in a patient, who recently traveled to tropics CBC: eosinophilia. TOW?;
endocytosed RBCs (distinction from luminal ameba)
44. Stool microscopy to confirm amebic dysentery should reveal characteristic trophozoites of Entamoeba histolytica w/
Metronidazole + iodoquinol
45. Rx of amebic dysentery involves
Serology for E. histolytica
46. Abscesses in liver or peritonitis in travelers w/ or w/o hx of amebic dysentery is confirmed by
47. A boar hunter develops dysentery after eating meat at campsite O & P test should reveal a ciliate parasite, known as
intestinal obstruction; cholangitis; liver abscess, in children; Ascaris lumbricides
48. Most likely cause of chronic abdominal pain, diarrhea
49. Ova & Parasite test using microscopy for oval eggs (with a thick coarse shell) in stool confirms
50. A child has stomach ache, distended abdomen, poor appetite. "Pearl-colored earthworm"-like organisms in the stool. Major immune response against this infection?
51. DOC of ascariasis is
52. Vomiting, cramping, diarrhea, epigastric pain, weight loss in an immigrant from developing country is caused by
53. DOC of strongyloidosis is
54. Pt w/ AIDS (low CD4+ counts) develops pulmonary infiltrates (+ eosinophilia) and/or gram negative sepsis. TOW?
Hookworm (Necator americanas) infection
55. Weakness, fatigue, lightheadedness, dyspnea, pruritis, pallor; iron-deficiency anemia; eosinophilia (hx of outdoor activity). TOW?;
56. Fever, periorbital edema, subconjunctival hemorrhages, muscle weakness, and rash, after eating undercooked pork (Lab: eosinophilia., ↑CPK, ↑LDH &). TOW?
Diphyllobothriasis (fish tapeworm)
57. Abdominal pain, bloating, altered appetite after ingestion of sushi. CBC: megaloblastic anemia, leukocytosis/eosinophilia. TOW?
Proglottids in stool
58. Dx of tape worm infection is confirmed by
59. Tape worm infections are treated with broad-spectrum agent
Schistosoma mansoni (Africa) S. japonicum (Far East)
60. Cause of fever, lymphadenopathy, hepatosplenomegaly in an immigrant from Africa or Orient pt recalls wading in stagnant water. RUQ ultrasound (+); CBC: eosinophilia
Large eggs with lateral spine.
61. Microscopy of stool in chronic stage of schistosomiasis reveals
62. Chronic stage of schistosomiasis is treated with
Inactivated HAV vaccine
63. Patient with acute jaundice is HAV IgM (+)household contact should receive for prophylaxis;
Acute HBV infection
64. Patient with jaundice for < 1 week has HBsAg (+), Anti-HBc IgM (+). TOW?
65. Multiple sex partners, IDU, infants born to infected mothers are risk groups for which hepatitis virus
66. This is an enveloped, double stranded DNA virus w/ ss-break transmitted by infective body fluids. TOW?;
Resolved hepatitis B
67. This asymptomatic man has hep serology profile of HBsAg (-), Anti-HBs (+), Anti-HBc IgG (+), Anti-HBc IgM (-). TOW?
Chronic active hepatitis B
68. This man has jaundice and is HBsAg (+) > 6 months, Anti-HBs (-), HBeAg (+), Anti-HBc IgG (+), HBV DNA > 20,000 IU/ml. TOW?
Peg-IFNα 2a + lamivudine (or cidofovir)
69. This man has jaundice and is HBsAg (+) > 6 months, HBeAg (+) and evidence of necroinflammation. He should receive
Inactive HBsAg carrier
70. This man has no jaundice, but HBsAg (+) >6 months, Anti-HBs (-), Anti-HBc IgG (+), HBeAg (-), persistently normal ALT. TOW?
71. This man, at the time of annual physical exam, reveals Anti-HBs (+) and other markers are (-). TOW?
HCV RNA > HCV IgG
72. Virologic confirmation of chronic jaundice in a HBV-immunized pt w/ IDU or hemodialysis is based on
HCV RNA virus
73. More chronicity of HCV (than HBV) is due to immune-evasive quasispecies generated during replication (in blood) of error-prone
74. Fulminant hepatitis in a patient, who has multiple sexual partners and is HBsAg (+) HBcIgM (-), can be fatal due to what?;
75. Cause of acute onset of jaundice, nausea, right-upper quadrant pain, hepatomegaly in pregnant women in India
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