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Medication Formulary

Terms in this set (66)

Canagliflozin
Invokana
Dapagliflozin
Farxiga
Dulaglutide
Trulicity
Empagliflozin
Jardiance
Glipizide
Glucotrol
Glyburide
Diabeta or Glynase
Insulin aspart
Novolog U-100
Insulin degludec
Tresiba U100 and U200
Insulin glargine
Lantus U100, Basaglar U100, Toujeo U300
Insulin lispro
Humalog U100 and U200
Linagliptin
Tradjenta
Liraglutide
Victoza
Metformin
Glucophage, Glumetza, or Fortamet
Pioglitazone
Actos
Pramlintide
Symlin
Saxagliptin
Onglyza
Sitagliptin
Januvia
Glyburide + Metformin
Glucovance
Sitagliptin + Metformin
Janumet
Linagliptin + Empagliflozin
Glyxambi
Metformin Initial dosing
500 mg BID or 850 mg d
Metformin max dose
2 gm / day
Metformin recommendation GFR >= 60
Monitor SCr annually
Metformin recommendation GFR < 60 and >= 45
Monitor Sir every 3-6 months
Metformin recommendation GFR <45 and >=30
Not recommended to start, Reduce dose by 50%, monitor SCr every 3 months
Metformin recommendation GFR < 30
Do not start, stop metformin
Metformin SE
Real dysfunction, contraindicated in HF 3 & 4, risk of LA, GI effects, vitamin B12 malabsorption and/or deficiency
Sitagliptin dosing for CrCl > 50
100 mg d
Sitagliptin dosing for CrCl 30-50
50 mg d
Sitagliptin dosing for CrCl < 30 or with ESRD on dialysis
25 mg d
Saxagliptin dosing
2.5 - 5 d
Saxagliptin dosing with CrCl < 50
2.5 mg d
Linagliptin dosing
5 mg d
Linagliptin, Saxagliptin, and Sitagliptin AE
Nasopharyngitis, URI, HA, some acute pancreatitis, possible joint pain and HF risk
Canagliflozin dosing CrCl > 60
100 mg d
Max: 300
Canagliflozin dosing CrCl 45-60
Max: 100 mg d
Canagliflozin dosing CrCl < 45
Do not start, discontinue
Dapagliflozin dosing CrCl > 60
5 mg d
Max: 10 mg d
Dapagliflozin dosing CrCl < 60
Do not start, discontinue
Empagliflozin dosing CrCl > 45
10 mg d
Max: 25 mg d
Empagliflozin dosing CrCl < 45
Do not start, discontinue
Canagliflozin, Dapagliflozin, and Empagliflozin AE
UTI, female genital fungal infections, increase urination, DKA, hypoglycemia, hypotension, hyperkalemia, increase cholesterol
FDA warnings for Canagliflozin and Dapagliflozin
AKI
FDA warnings for Canagliflozin
Bone fracture and decrease BMD
Glipizide dosing
2.5 - 5 mg d
Max: 40 mg
Glyburide dosing
Diabeta: 1.25 - 5 mg d MAX: 20
Glynase: 1.5 - 3 mg d MAX: 12
Glyburide and Glipizide AE
Hypoglycemia, weight gain, GI upset, leukopenia, thrombocytopenia, aplastic anemia, allergic skin reactions, photosensitivity
Pioglitazone Dosing
15-30 mg d
Max: 30-45 mg d
Titrate dose of pioglitazone every
12 weeks
Pioglitazone AE
Hepatotoxicity, resumption of ovulation, exacerbations of HF, increased edema, macular edema, increase fracture risk, increased CV death and MI
Pramlintide T1 dosing
15 mcg and titrate up by 15 to 30-60 mcg
Pramlintide T2 dosing
60 mcg and titrate up to 120 mcg
Pramlintide AE
Severe hypoglycemia, N/Vm anorexia
Victoza dosing
0.6 mg d for 7 days then 1.2-1.8 d
Trulicity dosing
0.75 -1.5 mg weekly
Trulicity and Victoza AE
N/V, hypoglycemia, pancreatitis, BBW for thyroid c-cell tumor
T1 insulin dosing
0.5-0.6 U/kg/day
50-70% basal
30-50% bolus
T2 insulin dosing ADA
0.1-0.2 U/kg/day
T2 insulin dosing AACE
A1C < 8% = 0.1-0.2 U/kg/day
A1C >8% = 0.2-0.3 U/kg/day
Insulin therapy AE
Hypoglycemia, weight gain, lipohypertrophy, lipoatrophy
-gliptin
DPP-4 inhibitors
-agliflozin
SGLT2
Glyburide, Glipizide, Glimepiride
Sulfonylureas
-glinide
Meglitinides
-glitazone
TZDs
-tide
GLP1 agonist
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