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Test 3 Nursing Vocab
Terms in this set (54)
The movement of the drug into the bloodstream
requires a carrier, such as an enzyme or protein, to move the drug against a concentration gradient.
When 2 drugs are administered in combination, and the response is increased beyond what either could produce alone.
Adverse Drug Reaction (ADRs)
unintentional, unexpected reactions to drug therapy that occur at normal drug dosages
Activate receptors and produce a desired response
This kind of drugs administered together, one drug reduces or blocks the effect of the other.
Drugs that prevent receptor activation and block a resonse.
refers to the percentage of administered of administrated drug avalible for activity.
The process by which the body chemically changes drugs into a form that can be excreted. Hint... B
Blood-Brain Barrier (BBB)
Blood vessels in the brain have a special endothelial lining where the cells are pressed tightly together.
Drug moves across the cell membrane from an area of higher concentration to one of lower concentration.
The movement of the drug from the circulation to body tissues.
The body's physiologic response to changes in drug concentration at the site of action.
Altered or modified action or effect of a drug a result of interaction with one or multiple drugs
When drug levels exceed the therapeutic range
Duration of Action
The length of time the drug exerts a therapeutic effect.
Fillers and inert substances -- such as simple syrup,etc...
Elimination of drugs from the body
Relies on carrier protein to move the drug from an area of higher concentration to an area of lower concentration.
First- Pass Effect
How the drugs are inactivated by liver.
Drugs able to exit blood vessels and reach their sites of action
the time it takes for the amount of drug in the body to be reduced by half
the site on the receptor at which drugs bind
large initial dose
the point at which increasing a drug's dosage no longer increases the desired therapeutic response
The process by which the body chemically changes drugs into a form that can be excreted. Hint... M...
drugs that affect multiple receptors
time it takes for drug to reach the min. effective concentration (MEC)
occurs through 2 processes - diffusion and facilitated diffusion
the drug reaches its highest concentration in the blood
peak drug level
highest plasma concentration can be determined by measuring peak and trough levels
the study of the effects of drugs on the body
study of genetic factors that influence an individual's response to a specific drug
study of how genetics play a role in a person's response to drugs
the process of drug movement throughout the body that is necessary to acheive drug action
a skin reaction caused by exposure to sunlight
the process by which cells carry a drug across their membrane by engulfing the drug particles in a vesicle
a drug response not attributed to the chemical properties of the drug
refers to the amount of drug needed to elicit a specific physiologic response to a drug
when the amount of drug being administered is the same as the amount of drug being eliminated
Refers to an acute, rapid decrease in response
therapeutic drug monitoring (TDM)
checking serum level
therapeutic index (TI)
describes the relationship between the therapeutic dose (ED50) of a drug and the toxic dose (TD50) of a drug.
trough drug level
lowest plasma concentration of a drug, and it measures at which the drug is eliminated
drops, ointments, or sprays - eyedrops, eye ointments, eardrops, nose drops
infusion of blood directly into the bone marrow
administered via injection
Z- track technique
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