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RBC Morphology

Ultimate set WBC / RBC Morphology normals and abnormal Immunology Blood Cells ID
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Acanthocyte/Spur Cell
Agglutination
Anisocytosis
Basophilic Stippling
Dacrocyte
Echinocyte/Burr Cells
Ghost Cells
What is the type of cell with the RED arrow?
Heinz Bodies
Howell Jolly Bodies
Keratocytes
Macrocyte
Microcytes
Nucleated RBC
Rouleaux / Cold agglutination
Schistocyte/Shizocyte
Spherocyte
Stomatocyte
Target Cell/Leptocyte/Codocyte
anisocytosis
anisochromia
polychromia
macrocytes
poikiocytosis
pelger-huet
codocytes
target cell
elliptocytes
crenated RBC
burr cell
acanthocytes
schistocytes
blister cell
drepanocyte / sickle cell anemia
Hb C crystal
dacrocytes
stomatocytes
smudge cell
spherocytes
rouleax
myeloblast
myeloblast
myeloblast
promyelocyte
promyelocyte
monocyte
myelocyte
promyelocyte
myelocyte- Eosin & Basophil
myelocyte
myelocyte & metamyelocyte
metamyelocyte
metamyelocyte
Spherocytes
Ovalocytes
Target cells
Stomatocytes
Sickle Cells
Knizocytes
Teardrop
Burr Cells
Crenated Cells
Schistocytes
Keratocytes
Acanthocytes
Blister cells
Rouleaux
HJ Bodies
Cabot rings
Basophilic Stippling
Pappenheimer bodies
Heinz Bodies
RBC and Neutrophil
Lymphocyte and Platelet
Other than RBC's what are the two things in this picture
Monocyte (Right) Neutrophil (seg, left)
Echinocytes

RBC with small, uniform spines surrounding cell
Most common cause of formation is an in-vitro artifact which is called crenation.
Acanthocytes

spur cells, altered lipid metabilsm, liver disease
Hemangiosarcoma
Spherocytes

lack of central pallor, smaller than normal. More likely seen in dogs, reduced membrane- macrophage destruction. Immune mediated disease, Hemolytic anemia, transfusion with rejection
Codocytes

target cells, specific leptocyte, common in non-regenerative anemia.
Heinz bodies

round inclusions from disruption in hemoglobin. May be seen in cats normally. Stain blue
Tylenol
onion or garlic
Hyperthyroidism
Lymphosarcoma
Howell jolly bodies

nuclear remnants, response to anemia, usually cleared by spleen
Ghost Cells

a dead cell in which the outline remains visible, but whose nucleus and cytoplasmic structures are not stainable. A red blood cell after loss of its hemoglobin
Schistocytes

some of the irregular shapes appear as helmet cells. Fragments of RBC's, indicative of intravascular hemolysis- mechanical damage to RBC's in circulation. Finding is typical in DIC
Rouleaux

organized stacking or chains of RBC's, normal in equine, suggests inflammatory disease in other species
Hyper-segmented Neutrophil

Greater than 4-5 segments, aged neutorphil, often seen in chronic infections, V-B-12 deficiency (Giant Schnauzer)
acanthocyte
echinocyte
heinz body
howell-jolly body
hypochromasia
ovalcytes
pappenheimer
schistocyte
sickle cell
stomatocyte
target cell
tear drop
ansiocytosis

Abnormal variation in size and color of RBC
poikilocytosis

abnormal variation in shape of RBC
hypochromia

pale cells
macrocytosis

large red blood cells
nucleated red cells
basophillic stippling

punctuate stippling of cell
sickle cells
target cells
cells with dark center and periphery and clear ring in between
spherocytes
spherical cells without pale centers
shistocytes
irregularly contracted cells; fragments
Rouleaux
a clump of red blood cells that appear to be stacked like a roll of coins
agglutination
clumping of RBC's
polychromasia
Term for a pale-blue RBC in routine stains, due to RNA content
anisocytosis
presence of red blood cells of unequal size
hypochromasia
little or no color in cell due to inuffeicient Hb with in the cell. Low Iron.
poikilocytosis
Cells are irregularly shaped
echinocytes
evenly spaced crenation, non-specific disease, rattlesnake envenomation, blood transfusion
acanthocytes
spur cells. resemble creanated cells. have multiple irregularly spaced rounded or clublike projections over entire surface of cell. result from alterations in cell membrane, often seen with kidney or liver disease, hemangiosarcoma, DIC, GN
stomatocytes
uniconcave erythrocytes with mouth like clear area near cell center; a few in a blood smear are insignificant; hereditary in some breeds (alaskan malamutes, schnauzers)
schistocytes
Fractured or fragmented RBC. microangiopathy, DIC, iron deficiency, liver disease, heart failure, GN, hemangiosarcoma
keratocytes
intact or ruptured vesicles on edge of RBC, seen in iron deficiency anemia, liver disease
spherocytes
Sphere spaed, lack central pallor. IMHA, zinc toxicity, blood parasites, bee sting, snake envenomation, transfsion
leptocytes, target cells
Cells with less volume and are 'flattened out.' Folded cell has transverse fold. Target cell looks like a target. Both are associated with chronic anemia, liver disease,dyserythropoiesis
eccentrocytes
Shifting of Hb to one side of the cell, resulting in a clear zone outlined by membrane; oxidant injury: onions, tylenol, vitamin K
Heinz bodies
"nose" of Denatured Hemoglobin, stains well with New Methylene Blue stain, Can be seen in cats, Can lead to anemia. diabetes, hyperthyroidism, lymphoma, or normal
ovalocytes
oval shaped, hereditary in dogs, myelofibrosis, MDS, cats with bone marrow disease, hepatic lipidosis
dacrocytes
tear drop shaped. results from failure of the cell to resume its normal shape after passage thru capillaries. Or, can also be an artifact of smear preparation. Tails same direction= artifact of staining. tails opposite direction= myelofibrosis.
basophilic stippling
deep blue stippling due to ribosomes. regenerative anemia, lead poisoning.
siderocytes
clustered blue dots of iron; lead poising,
Howell-Jolly
remnants of chromatin, severe anemias or aspleenia

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