spur cells. resemble creanated cells. have multiple irregularly spaced rounded or clublike projections over entire surface of cell. result from alterations in cell membrane, often seen with kidney or liver disease, hemangiosarcoma, DIC, GN
uniconcave erythrocytes with mouth like clear area near cell center; a few in a blood smear are insignificant; hereditary in some breeds (alaskan malamutes, schnauzers)
Fractured or fragmented RBC. microangiopathy, DIC, iron deficiency, liver disease, heart failure, GN, hemangiosarcoma
intact or ruptured vesicles on edge of RBC, seen in iron deficiency anemia, liver disease
Cells with less volume and are 'flattened out.' Folded cell has transverse fold. Target cell looks like a target. Both are associated with chronic anemia, liver disease,dyserythropoiesis
Shifting of Hb to one side of the cell, resulting in a clear zone outlined by membrane; oxidant injury: onions, tylenol, vitamin K
"nose" of Denatured Hemoglobin, stains well with New Methylene Blue stain, Can be seen in cats, Can lead to anemia. diabetes, hyperthyroidism, lymphoma, or normal
oval shaped, hereditary in dogs, myelofibrosis, MDS, cats with bone marrow disease, hepatic lipidosis
tear drop shaped. results from failure of the cell to resume its normal shape after passage thru capillaries. Or, can also be an artifact of smear preparation. Tails same direction= artifact of staining. tails opposite direction= myelofibrosis.
deep blue stippling due to ribosomes. regenerative anemia, lead poisoning.
clustered blue dots of iron; lead poising,
remnants of chromatin, severe anemias or aspleenia
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