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Terms in this set (30)

Changes associated with chronic bronchitis include: hypertrophy and hyperplasia of the bronchial mucous glands, increased goblet cells, ciliary damage, squamous metaplasia of the columnar epithelium, and chronic leukocytic and lymphocytic infiltration of bronchial walls.

Widespread inflammation occurs, leading to airway narrowing and mucus within the airways—all producing resistance in the small airways and, consequently, a severe ventilation-perfusion imbalance.
Widespread inflammation occurs, leading to airway narrowing and mucus within the airways—all producing resistance in the small airways and, consequently, a severe ventilation-perfusion imbalance.
Changes associated with emphysema include: recurrent inflammation associated with the release of proteolytic enzymes from lung cells that causes abnormal, irreversible enlargement of the air spaces distal to the terminal bronchioles.

The amount of alveolar surface area available for gas exchange decreases.

This enlargement leads to the destruction of alveolar walls in the distal or terminal airways, which results in a breakdown of elasticity. Elastic recoil is reduced, limiting airflow.

Supporting alveolar structures are lost, leading to narrowing of the airway, which further limits airflow.

The airways and lung parenchyma are involved.

These changes result in impaired carbon dioxide and oxygen exchange.
The amount of alveolar surface area available for gas exchange decreases.
This enlargement leads to the destruction of alveolar walls in the distal or terminal airways, which results in a breakdown of elasticity. Elastic recoil is reduced, limiting airflow.
Supporting alveolar structures are lost, leading to narrowing of the airway, which further limits airflow.
The airways and lung parenchyma are involved.
These changes result in impaired carbon dioxide and oxygen exchange.