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Terms in this set (18)
-opioid partial agonist
-at low doses, it treats opioid withdrawal (high doses it'll ppt withdrawal)
-can also treat pain
partial agonist of nicotinic receptors with antagonist properties
-treats nicotine withdrawal by blocking full stimulation of receptors
-even if you smoke, you get no pleasure, but also no withdrawal
-treats nicotine withdrawal and depression
partial opioid agonist (therefore can ppt withdrawal if used with a full agonist)
5-HT(1A) agonist; treats generalized anxiety disorder
-no sedation, addiction, or tolerance!
-does NOT work for depression
which has more side effects? amitriptyline or nortriptyline?
amitriptyline (its tertiary)
how do TCAs cause cardiotoxicity?
inhibit sodium channel conduction which leads to arrhythmias
what is unique about desipramine among other TCAs?
it's less sedating and has a higher seizure threshold
treatment for serotonin syndrome?
cyproheptadine (5-HT(2) receptor antagonist)
treatment for TCA OD?
who do you NOT give buproprion to?
bulimic patients-cause seizures
-treats depression and panic disorder
treats depression and diabetic peripheral neuropathy
alpha-2 antagonist, 5-HT antagonist
blocks 5-HT uptake
-treats insomnia, NOT depression bc too high doses would be required
big plus of buproprion
no sexual side effects compared to other antidepressant
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