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Biochemistry Exam 3- Textbook questions

Terms in this set (30)

Vitamins typically act as ______ in the reactions they participate in.
Coenzymes
Which animal cannot synthesise vitamin C from glucose?
Guinea pig
Vitamin C is known to participate in which reaction type?
Hydroxylation
Vitamin C is known to participate in all of the following except:
Bile acids
Collagen
Epi
Carnitine
CH
CH
Absorption of which of the following from the digestive tract is thought to be enhanced by vitamin c?
Iron
Which of the following is a normal degradation product of vitamin C
Oxalate
Vitamin C is known to known to be concentrated in all of the following locations except
Skeletal muscle
CNS
SNS
Leukocytes
Adrenal medulla
Skeletal muscle
Glutathione participates in:
Dehydroascorbate reduction
Which of the following glycolytic reactions involves thiamin:
Pyruvate to acetyl coA
A thiamin deficiency can be judged by measuring the activity of which one of the following enzymes in mature erythrocytes:
Transketolase
Which is a FAD- containing enzyme:
Glutathione reductase
Conversion of riboflavin to its coenzyme derivatives occurs to the greatest extent in which organ?
Liver
Riboflavin 5'-monophosphate (FMN)
Is formed by:
ATP dependent phosphorylation of riboflavin
Which of the following amino acids is used in the biosynthesis of nicotinate mononucleotide (NMN):
Tryptophan
A deficiency of which of the following B-complex vitamins would make it more difficult to convert Typ to NMN and therefore potentiate a niacin deficiency:
Pyridoxine
Niacin deficiency is best associated with:
Pellagra
Which of the following enzymes are best associated with niacin (vitamin B3):
Dehydrogenases
4-Phosphopantetheine is:
A prosthetic group for acyl carrier protein
Coenzyme A.SH is associated with all of the following except:
Porphyrin biosynthesis
Ketone body synthesis
Cholesterol synthesis
Mito B-oxidation of FAs
Cytoplasmic glycogen synthesis
Cyto glycogen synthesis
Acyl-CoA compounds are properly referred to as:
Thioesters
Lipoic acid:
A B-complex vitamin
Which TCA cycle enzymes are associated with pantothenate?
Succinate thiokinase and citrate synthase
Pantothenic acid:
Is filtered by the kidneys and excreted in the urine
The oxidative decarboxylation of pyruvate at acetyl CoA requires:
Thiamine, lipoic acid, niacin, pantothenic acid, and pyruvate dehydrogenase
Which one of the following compounds, contained in egg white, binds strongly with biotin in the digestive tract, thus preventing its absorption:
Avidin
Biotin is a coenzyme for certain:
Carboxylation reactions
Which one of the following mitochondrial reactions involves biotin?
Propionyl-CoA —> Methylmalonyl-CoA
Biotin is involved in ketone body production from which one of the following amino acids?
Leucine
Approximately 70-80% of vitamin B6 in mammalian organisms is associated with which enzyme?
Adipolytic triglyceride lipase
Pyridoxine deficiencies are best associated with increased urinary excretion of:
AA metabolites
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