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Immune System Review Questions

Terms in this set (20)

What kinds of molecule attract phagocytes?
Opsonins
What step in phagocytosis does an opsonin help with?
Chemotaxis
Adherence
Ingestion
Phagosome maturation
Microbial killing
Elimination
Chemotaxis
What types of molecules can bind to TLRs?
PAMPs
Flagellin
dsRNA
Lipid A
Peptidoglycan
viral RNA
Once a molecule binds to a TLR, what actions could be triggered?
Inflammation, anti-viral immune response (cell mediated), T cell stimulation, Interferons
What sort of molecule is an interferon?
Protein
Interferons stimulate production of what?
AVPs
What molecule causes inflammation?
Histamine
What are the benefits of vasodilation?
Increased blood flow
What molecules cause increased blood vessel permeability?
Prostaglandins
Leukotrienes
What are the benefits of increased blood vessel permeability?
Movement of microbial chemicals and clotting proteins
What molecules induce migration of the pahgocytes?
PAMPs
Leukotrienes
What molecules trigger fever?
Pyrogens
What type of lymphocytes are involved in antibody immunity?
B
Th2
What type of lymphocytes are involved in cell mediated immunity?
Tc
Th1
What are the 3 functions of antibodies?
Neutralization
Opsonization
Agglutination
What does perforin do?
Put hole in target cell
What does granzyme do?
Initiates apoptosis
What are plasma cells?
Cloned B cells
What are memory cells?
Cloned but specialized to live longer. Can be B or T cells and are activated quickly in secondary immune response
Why so many layers of activation before a plasma cell will start secreting antibodies?
Make sure it is really a pathogen and needs the extra immunity help.
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