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Phys 70/71 The Liver as an Organ
Terms in this set (42)
5 major functions of the liver
Filtration and storage of blood
metabolism of carbs, fats, protein, and hormones
formation of bile
storage of vitamins and iron
formation of coagulation factors
Hepatic cells are continuously exposed to ____ blood
where do portal venules receive their blood supply from via portal veins?
another name for kupffer cells
perisinusoidal spaces that connect lympahtic vessels in the interlobular septa
Spaces of Disse
how much of the resting cardiac output does the liver get
does the liver have high or low pressure circulation?
what is NASH?
fatty liver causing cirrhosis
- alcohol can also cause cirrhosis
liver inflammation caused by obesity and DMII (diabetes mellitus)
Nonalcoholic fatty liver disease
What are some non alcohol/non-fat causes of cirrhosis
ingestion of poison such as carbon tetrachloride
bile duct obstruction
infectious process of bile duct
viral disease such as infectious hepatitis
how long does it take to die from portal hypertension?
excessive loss of fluids from capillaries into the lumens and walls of the intestines
the liver forms about half of the ____ for the body
how does ascites develop?
high hepatic vascular pressure
this causes fluid to transudate into lymph and leak out of the liver capsule into the abdominal cavity
Besides the liver producing serum into the abdomen, how else can portal hypertension cause ascites?
High capillary pressure in the GI tract resulting in edema of the gut wall and transudation of fluid through the serosa of the gut.
important growth factor of hepatocytes?
where is it produced?
hepatocyte growth factor (HGF)
mesenchymal cells> not hepatocytes
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