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Ch 18 The Blood

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Blood does not
produce plasma hormones
the buffy coat doesnt contain
erythrocytes
hematocrit is __ of the total blood volume
37-52%
__ is not found in plasma
glycogen
__ is a protein not commonly found in plasma
hemoglobin
__ is the most abundant protein in plasma
albumin
__ would not decrease colloid osmotic pressure (COP) in blood
a diet predominantly based on red meat
serum is essentially identical to plasma except for the absence of
fibrinogen
tissues can become edematous (swollen) when
there is a dietary protein deficiency
myeloid hemopoiesis in adults happens in the
red bone marrow
the viscosity of blood is due more to __ than to any other factor
erythrocytes
erythrocytes transport oxygen and serve to
transport carbon dioxide
most oxygen is transported bound to
heme groups in hemoglobin
if all the 280 million molecules of hemoglobin contained in RBCs were free in the plasma,
it would significantly increase blood osmolarity
an increased erythropoietin (EPO) output by the kidneys would lead to all of the following except
increased hypoxemia
many RBCs die in the
spleen and liver
all these can lead to polycythemia except
iron deficiency
__ is more likely to cause anemia than any of the other factors below.
renal insufficiency
anemia has these potential consequences except
blood viscosity is increased
what is the final product of the breakdown of the organic nonprotein moiety of hemoglobin
bilirubin
correction of hypoxemia is regulated by
a negative feedback loop
a deficiency of __ can cause pernicious anemia
vit B12
sickle-cell disease is not
a cause of malaria
the ABO blood group is determined by __ in the plasma membrane of RBCs
glycolipids
type A blood can safely donate RBCs to __ and can receive RBCs of type __
AB; O
Type AB blood has __ RBC antigens
A and B
RhoGAM is an antibody given to RH- women who give birth to a RH+ child. RhoGAM is what type of plasma protein
gamma globulin
the universal donor is
0, RH -
an individual had type B, Rh+ blood. The individual has __ antigens and can produce __ Antibodies
B and D; A
the main reason why an individual AB, Rh- cant donate blood to an individual A, Rh+ is because
Anti-B antibodies in the recipient will agglutinate RBCs of the donor
A woman's first pregnancy is normal but her second pregnancy results in hemolytic disease of the newborn (HDN), or erythroblastosis fetalis. The second child needed a transfusion to completely replace the agglutinating blood. The mother is most likely type ___ and both children are most likely ____.
A, Rh-negative; B, Rh-positive
these are the least abundant formed elements
basophils
these are the most abundant agranulocytes
lymphocytes
differential count of __ typically increases in response to bacterial infections
neutrophils
__ aid in the bodys defense processes by secreting histamine (vasodilator) and heparinn (anticoagulant)
basophils
leukopoiesis begins with the differentiation of
pluripotent stem cells (PPSCs)
some lymphocytes can survive for
decades
a total count above __ WBCs is called leukocytosis
10,000
all these can cause leucopenia except
dehydration
this figure shows the formed elements of blood. What does 7 represent
lymphocyte
platelets do Not secrete
thrombopoietin
the cessation of bleeding is specifically called
hemostasis
thromboplastin
initiates the extrinsic pathway of coagulation
when a clot is no longer needed, fibrin is dissolved by
plasmin
all of these prevent the spontaneous formation of a clot except
the presence of tissue thromboplastic
platelets release__, a chemical vasoconstrictor that contributes to the vascular spasm
serotonin
the structural framework of the blood clot is formed by
a fibrin polymer
most strokes and heart attacks are caused by the abnormal clotting of blood in an unbroken vessel. Moreover, a piece of the __ clot may break loose and begin to travel in the bloodstream as an __
thrombus; embolus
__ participates in the extrinsic mechanism only
thromboplastin
most clotting factors are synthesized in the
liver