Upgrade to remove ads
Chapter 21: Inflammation - Fever
Terms in this set (24)
A localized response triggered by any stimulus that kills cells or injures tissue
When is inflammation triggered?
Swelling (tumor), Redness (rubor), Heat (calor), Pain (dolor)
What are the cardinal signs and symptoms of inflammation?
Temporary repair and barrier against pathogens - retards spread of pathogens into surrounding areas - mobilization of local and systemic defenses and facilitation of repairs - alerts adaptive immune system
What are the 4 effects of inflammation?
Begins with chemicals released into ECF by injured tissues, immune cells, blood proteins
What is the first step in initiating inflammation?
Macrophages and epithelial cells of boundary tissues bear Toll like receptors (TLR's)
What is the second step of inflammation?
11 types of TLR's recognized specific classes of infecting microbes
What is the third step of inflammation?
Activated TLR's trigger release of cytokines that promote inflammation
What is the fourth step of inflammation?
Release prostaglandins, proteins, and potassium ions
What do injured cells release into IF?
Changes interstital environment and stimulates mast cells
The release of certain chemicals by injured cells changes and stimulates what?
Histamine (increases capillary permeability and vasodilation) and Heparin (inhibits clotting)
What do mast cells release?
Fluid containing clotting factors and antibodies
What causes local swelling?
Swelling pushes on nerve endings, and pain from bacterial toxins, prostaglandins, and kinins
How does swelling cause pain?
Moves foreign material into lymphatic vessels and delivers clotting proteins and complement
An increase in capillary permeability leads to the exudate to tissues, resulting in what?
Break down bacteria, attract phagocytes, and stimulate histamine relaese
How do complements affect inflammation?
Activated neutrophils attack debris and bacteria
How do activated neutrophils assist in inflammation and tissue repair?
Phagocytes and foreign proteins activate body's specific defense system
How do phagocytes and foreign proteins assist in inflammation and tissue repair?
Form fibrin mesh, which isolates injured area so invader cannot spread
What do the clotting factors form/what do they do?
Macrophages clean up pathogens and cell debris
How do macrophages assist in inflammation and tissue repair?
Fibroblasts form scar tissue
How do fibroblasts assist in inflammation and tissue repair?
Necrosis, pus, abscess
What are products of inflammation?
Local tissue destruction in area of injury
What is necrosis?
Mixture of debris and necrotic tissue
What is pus?
Pus accumulated in an enclosed space
What is an abscess?
A high body temp - increases metabolism, accelerates defenses, inhibits some viruses and bacteria, and can cause liver and spleen to sequester iron and zinc
What does a fever do to the body?
This set is often in folders with...
CONCEPT 23 IMMUNITY
Chapter 21: Pathogens - 3 functional characteristi…
Chapter 21: Immunological Surveillance -
Chapter 21: Pyrogens - Tolerance
You might also like...
Chapter 9 Pathophysiology- Inflammation
Other sets by this creator
Chapter 11: Nuclear chemistry
Chapter 10: Acids and Bases
Chapter 9: Solutions
Chapter 8: Gases, liquids, and solids
Other Quizlet sets
lesson 11 ap exam 3
EQM 351 Exam 1
KINE 290 - Quiz 5
Pharm Drugs for Viral Infections