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ATI Pharm Mega File

The combined A/B + drugs, should be all needed
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Diazepam (Valium)
Benzodiazepine
Muscle relaxant, antispasmodic, sedative (enhances GABA)
Treats anxiety disorders, muscle spasms, alcohol withdrawal
Side effects: CNS depression, amnesia,, respiratory depression
Physical dependence - do not d/c abruptly
Avoid other CNS depressants
Antidote: flumazenil (Romazicon)
Taper dose to d/c
Buspirone (BuSpar)
Treats anxiety disorders
Abuse less likely than other anxiolytics
No sedation
Does not potentiate other CNS depressants
Dizziness, nausea
Caution w/ liver or renal disease
Do not use w/in 14 days of MAOIs (hypertensive crisis)
May take weeks for full effect
Do not take w/ erythromycin, grapefruit juice
Paroxetine (Paxil)
SSRI (anxiety)
Prevents serotonin reuptake
Causes CNS stimulation (can cause insomnia)
Early: nausea, tremor, fatigue
Later: sexual dysfunction
Hyponatremia
Serotonin syndrome
Bruxism
GI bleeding
Taper slowly to d/c
Do not take w/ MAOIs or TCAs (serotonin syndrome)
Take in the morning, takes several weeks for full effects, take w/ food for GI effects
Amitriptyline (Elavil)
Tricyclic antidepressant (TCA)
Blocks NE, serotonin reuptake
Used for depression, migraines
Can cause orthostatic hypotension, anticholinergic effects, sedation, cardiac toxicity, decreased seizure threshold, sweating
Avoid St. John's wort (serotonin syndrome, antihistamines, anticholinergics, alcohol, CNS depressants, MAOIs
Fluoxetine (Prozac)
SSRI (depression)
Can cause sexual dysfunction, CNS stimulation, weight loss/gain, serotonin syndrome, withdrawal syndrome, hyponatremia, bruxism, rash, fatigue, GI bleeding
Do not take w/ MAOIs or TCAs, St. John's wort, lithium
Caution w/ Coumadin, NSAIDs (suppresses platelet aggregation)
Take in the morning, takes several weeks for full effects, take w/ food for GI effects
Phenelzine (Nardil)
MAOI (increases NE, dopamine, serotonin)
Treats depression, bulemia, OCD
Can cause CNS stimulation, orthostatic hypotension, cheese effect, local rash (transdermal)
Do not take w/ SSRIs, caution w/ TCAs
Bupropion HCl (Wellbutrin)
Atypical antidepressant
Inhibits dopamine uptake
Can cause anticholinergic effects, seizures, suppress appetite
Avoid MAOIs
Lithium
Mood stabilizer
Used for bipolar disorder
Blocks serotonin receptors, decreases neuronal atrophy/increases neuronal growth
Can cause GI distress, fine hand tremors, polyuria and thirst, weight gain, renal toxicity, goiter and hypothyroidism, bradydysrhythmias, hypotension, electrolyte imbalance
Early toxicity: N/V/D, thirst, polyuria, muscle weakness, slurred speech
Low Na increases toxicity
NSAIDs increase toxicity
Avoid anticholinergics
Normal level 0.4-1.0mEq/L (toxicity > 1.5)
Carbamazepine (Tegretol)
Antiepileptic (also for bipolar, trigeminal neuralgia) (not for absence seizures)
Can cause blood dyscrasias (bleeding, bone marrow suppression), promotes ADH (edema, fluid overload), Stevens-Johnson
Hepatic autoinducer (alternate birth control, increase warfarin dosage)
Grapefruit juice (toxicity)
Phenytoin and phenobarbital decrease effects
Valproic acid (Depakote)
Antiepileptic (also bipolar)
Can use for absence seizures
Can cause N/V, hepatotoxicity, pancreatitis, thrombocytopenia
Increases levels of phenytoin and phenobarbital
Lamotrigine (Lamictal)
Antiepileptic (also bipolar)
Can cause double or blurred vision, Stevens-Johnson
Effect decreased by carbamazepine, phenytoin, phenobarbital
Half-life increased by valproic acid
Chlorpromazine (Thorazine)
Haloperidol (Haldol)
Conventional antipsychotic (positive symptoms)
Block dopamine, ACh, NE, histamine
Can cause:
Acute dystonia (treat w/ anticholinergics - benztropine/Cogentin or Benadryl) - EARLY
Parkinsonism (treat w/ antcholinergics or amantadine)
Akathisia (beta blocker, benzodiazepine, anticholinergic)
EPS or tardive dyskinesia - LATE
Neuroleptic malignant syndrome (d/c, antipyretics, Valium, dantrolene)
Anticholinergic effects, orthostatic hypotension, sedation, gynecomastia, seizures, sexual dysfunction, photosensitivity, agranulocytosis, dysrhythmias
Risperidone (Risperdal)
(Seroquel, Abilify, clozapine)
Atypical antipsychotic (positive and negative symptoms)
Block serotonin, some dopamine, NE, ACh, histamine
Can cause DM or loss of glucose control, weight gain, hypercholesterolemia (esp. olanzapine, clozapine)
Orthostatic hypotension, anticholinergic effects, agitation, tremors
Seroquel - cataracts, eye exam q 6 months
Clozapine - agranulocytosis
Contraindicated w/ dementia
Risk for stroke
Methylphenidate (Ritalin)
Amphetamine (Adderall)
CNS stimulant (increases NE, serotonin, dopamine)
Used for ADHD
Causes CNS stimulation, weight loss, CV effects, psychosis
Do not d/c suddenly
Avoid MAOIs (htn), caffeine (CNS stimulation), OTC cough and cold (sympathomimetic)
Increases levels of Coumadin
Atomoxetine (Strattera)
NSRI (not a stimulant) (blocks NE reuptake)
Used for ADHD
Minimal side effects - weight gain, N/V, hepatotoxicity
Caution w/ heart disease
Avoid MAOIs (htn)
Meds to aid w/ alcohol detox
Benzodiazepines (maintain vitals, decrease seizures, decrease symptom intensity)
Carbamazepine (seizures)
Clonidine (decreased ANS response)
Propranolol (decreased cravings, ANS response)
Disulfiram (Antabuse) - maintenance
Naltrexone (ReVia) - suppresses cravings, pleasurable effects of alcohol
Acamprosate (Campral) - decreased anxiety, restlessness
Meds to aid opioid withdrawal
Methadone (Dolophine) - transfers dependence to methadone, then wean off
Clonidine (decreased ANS effects, does NOT reduce cravings)
Buprenorphine, combine w/ naloxone - detox and maintenance, may decrease cravings
Meds to aid nicotine withdrawal
Bupropion (Zyban) - decreases cravings and withdrawal symptoms
Nicotine replacement (gum, patch)
Neostigmine (Prostigmin)
Cholinesterase inhibitor (cholinergic agonist)
Treats myasthenia gravis
Reverse neuromuscular blockade
Cholinergic side effects
Antidote: atropine
Levodopa/carbidopa (Sinemet)
Parkinson's (dopaminergic)
Can cause N/V, dyskinesias, orthostatic hypotension, CV stimulation, psychosis, discolored sweat/urine
Do not use w/ MAOIs
Proteins interfere w/ absorption
Pramipexole (Mirapex)
Parkinson's (dopamine agonist)
Can cause drowsiness, orthostatic hypotension, psychosis, dyskinesias, nausea
Allows for lower dose of levodopa
Caution w/ liver or kidney impairment
Benztropine (Cogentin)
Parkinson's (anticholinergic) (blocks ACh)
Can cause N/V, anticholinergic effects, antihistamine effects
Contraindicated w/ narrow-angle glaucoma
Amantidine (Symmetrel)
Parkinson's (dopamine releaser)
Antiviral
Can cause confusion, dizziness, anticholinergic effects, discoloration of skin
Phenobarbital (Luminal)
Barbiturate
Can be used for epilepsy
Can cause CNS depression
Phenytoin (Dilantin)
Hydantoin (antiepileptic)
Can cause gingival hyperplasia, hirsutism, phlebitis, speed shock, sedation, double vision, dysrhythmias, hypotension
Decreases effects of contraceptive, Coumadin, glucocorticoids
Avoid alcohol, Valium, Tagamet, CNS depressants
Gabapentin (Neurontin)
Antiepileptic
Can be used for neuropathy pain
Can cause drowsiness, nystagmus, edema
Succinylcholine (Anectine)
Neuromuscular blocking agent (depolarizing)
Fills ACh receptors and causes sustained depolarization
Reversal agent: Pseudocholinesterase enzyme
Monitor for respiratory arrest, hypotension
Watch for signs of malignant htn (administer dantrolene)
Monitor for hyperkalemia
Pancuronium (Pavulon)
Neuromuscular blocking agent (non-depolarizing)
Blocks ACh binding and inhibits depolarization
Reversal agent: neostigmine
Cyclobenzaprine (Flexeril)
Muscle relaxant/antispasmodic
Enhances GABA
Used for muscle spasms due to injury
Causes CNS depression
Physical dependence - do not d/c abruptly
Baclofen (Lioresal)
Muscle relaxant
Enhances GABA
Used for cerebral palsy, SCI, MS
Causes CNS depression, nausea, constipation, urinary retention
Do not d/c abruptly
Dantrolene (Dantrium)
Muscle relaxant (peripherally acting)
Inhibits muscle contraction by preventing Ca release in skeletal muscles
Used for cerebral palsy, SCI, MS, malignant hyperthermia
Causes CNS depression, hepatotoxicity, muscle weakness
Bethanechol (Urecholine)
Muscarinic (cholinergic) agonist
Used for urinary retention
Causes cholinergic side effects (SLUDGE)
Take on empty stomach
Oxybutinin (Ditropan)
Tolterodine (Detrol)
Muscarinic (cholinergic) antagonist
Used for overactive bladder
Causes anticholinergic effects
Avoid antihistamines, TCAs, phenothiazines
Zolpidem (Ambien)
Sedative-hypnotic (non-benzodiazepine)
Enhance GABA
Can cause daytime sleepiness
Low risk of abuse, tolerance, dependence
Avoid CNS depressants
Ramelteon (Rozerem)
Melatonin agonist
Used for insomnia
Can cause sleepiness, hormonal effects (amenorrhea, decreased libido, infertility, galactorrhea)
Take on empty stomach (fat decreases absorption)
Avoid CNS depressants
IV anesthetics
Barbiturate: thiopental (Pentothal)
Benzodiazepines: midazolam (Versed), diazepam (Valium)
Other: propofol (Diprivan), ketamine (Ketalar)
Opioid: Fentanyl (Sublimaze)
Can cause respiratory depression, CV depression, high risk for hypotension
Propofol: bacterial infection
Ketamine: hallucinations
Albuterol (Proventil, Ventolin)
Beta-2 agonist
Inhaled = short-acting, oral = long-acting
Rescue or maintenance (asthma)
Minimal adverse effects of inhaled
Oral can cause tachycardia and angina (alpha-1), tremors (beta-2 in skeletal muscle)
Beta blockers will cancel effects
MAOIs and TCAs increase risk of tachycardia and angina
Use before using glucocorticoid inhaler
Salmeterol (Serevent)
Beta-2 agonist
Long term maintenance for asthma
Theophylline (Theolair)
Methylxanthine
Used for long-term control of asthma
Therapeutic range: 5-15mcg/mL
Early toxicity: GI distress, restlessness
Late toxicity: dysrhythmias, seizures
Caffeine increases theophylline levels
Phenobarbital and phenytoin decrease levels
Tagamet and fluoroquinolones increase levels
Ipratropium (Atrovent)
Tiotropium (Spiriva)
Inhaled anticholinergic
Used for COPD, asthma
Cause anticholinergic effects
Contraindicated w/ peanut allergy
Caution w/ narrow-angle glaucoma and BPH
Beclomethasone diproprionate (QVAR)
(Pulmicort, Advair, Flovent)
Inhaled glucocorticoid
Maintenance for asthma
Can cause candidiasis
Prednisone (Deltazone)
(Prednisolone)
Oral glucocorticoid
Long term use can cause suppression of adrenal gland function, bone loss, hyperglycemia, myopathy, PUD, infection, edema, hypokalemia
Caution w/ K-wasting diuretics
Avoid NSAIDs (GI bleeds)
Must increase insulin or oral hypoglycemic doses
Hydrocortisone sodium succinate (Solu-Cortef)
Methylprednisone sodium succinate (Solu-Medrol)
IV glucocorticoids
Cromolyn sodium (Intal)
Anti-inflammatory (mast cell stabilizer)
Inhibits release of histamine
Used for chronic asthma, allergic rhinitis
Safest of all asthma meds
Montelukast (Singulair)
Leukotriene modifier
Long term asthma therapy
Take once daily at bedtime (oral)
Codeine
Opioid antitussive
Can cause drowsiness, respiratory depression, GI distress
Has potential for abuse
Avoid CNS depressants
Contraindicated w/ asthma, head trauma, liver/renal dysfunction, acute alcoholism
Dextromethorphan
Antitussive
Mild nausea, dizziness, sedation
Small potential for abuse
May cause high fever w/in 2 weeks of MAOIs
Guaifenesin (Mucinex)
Expectorant
Can cause GI upset, drowsiness, rash
Should increase fluid intake
Acetylcysteine (Mucomyst)
Mucolytic
Antidote for Tylenol poisoning
Used in CF, pulmonary diseases w/ lots of secretions
Can cause aspiration and bronchospasm (oral)
Smells like rotten eggs (mix w/ syrupy drink)
Phenylephrine
Decongestant
Alpha-1 agonist
Used for allergic rhinitis, common cold
Can cause rebound congestion w/ topical agents (faster, shorter duration)
Can cause CNS stimulation (rare)
Causes vasoconstriction (caution w/ htn, CAD)
Diphenhydramine (Benadryl)
Promethazine (Phenergan)
Antihistamine (1st generation)
Used for allergies, anaphylaxis, motion sickness, insomnia
Can cause sedation, anticholinergic effects, GI discomfort
Avoid CNS depressants
Loratidine (Claritin)
(Zyrtec, Allegra)
Antihistamine (2nd generation)
Non-sedating
Furosemide (Lasix)
Loop diuretic
Block Na and Cl reabsorption in ascending loop
Can be used w/ renal impairment
Used for pulmonary edema, edema caused by liver/cardiac/kidney disease, htn
Also used for hypercalcemia related to kidney stone formation
Can cause dehydration, hyponatremia, hypochloremia, hypotension, ototoxicity, hypokalemia (and hyperglycemia, hyperuricemia, decreased Ca and Mg)
Can cause dig toxicity due to hypokalemia, lithium toxicity due to hyponatremia
Antihypertensives have additive effect
NSAIDs reduce diuretic effect
Daily weights and I/O
Take early in the day
Hydrochlorothiazide (Hydrodiuril)
Thiazide diuretic
Blocks Na and Cl reabsorption in distal convoluted tubule
Cannot use w/ impaired renal function
Used for essential htn, edema of CHF/liver/kidney disease
Can cause dehydration, hypokalemia, hyperglycemia
Can cause dig toxicity due to hypokalemia, lithium toxicity due to hyponatremia
Antihypertensives have additive effect
NSAIDs reduce diuretic effect
Take early in the day
Spironolactone (Aldactone)
K-sparing diuretic
Blocks aldosterone (K retention, Na and water excretion)
Combined w/ other diuretics for K-sparing effects
Used for CHF, primary hyperaldosteronism
Can cause hyperkalemia, menstrual irregularities, impotence
Do not use w/ severe renal failure or anuria
Risk of hyperkalemia w/ ACE inhibitors, K supplements
Mannitol (Osmitrol)
Osmotic diuretic
Draws fluid into vascular space
Used for cerebral edema and to reduce intraocular pressure
Can cause heart failure, renal failure, fluid and electrolyte imbalances
IV infusion using filter needle (crystallization)
Captopril (Capoten)
ACE inhibitor
Blocks angiotensin II production causing vasodilation, Na/water loss, K retention, reduction of cardiac remodeling
Used for htn, CHF, MI, nephropathy
Ramipril to prevent MI,, stroke, death
Can cause first dose orthostatic hypotension, cough (bradykinin), hyperkalemia, rash and altered taste, angioedema, neutropenia
Can increase levels of lithium
NSAID use may decrease effects
Losartan (Cozaar)
ARB
Blocks action of angiotensin II causing vasodilation, Na/water loss, K retention
Used for htn, CHF, following MI, stroke prevention, nephropathy
No cough or hyperkalemia
Nifedipine (Procardia)
CCB
Blocks Ca channels (arterioles)
Used for angina, htn
Can cause reflex tachycardia, peripheral edema
Toxicity: administer Ca
Beta blockers can reduce reflex tachycardia
Grapefruit juice increases toxicity
Verapamil (Calan)
Diltiazem (Cardizem)
CCB
Block Ca channels (arterioles and heart)
Used for angina, htn, dysrhythmias, migraines
Can cause orthostatic hypotension, peripheral edema, constipation, bradycardia, HF, dysrhythmias
Toxicity: administer Ca
Can increase dig levels
Stagger beta blockers to avoid HF, AV block, bradycardia
Grapefruit juice increases toxicity
Prazosin (Minipress)
Alpha-1 blocker (sympatholytic)
Causes venous and arterial dilation, prostatic and bladder muscle relaxation
Used for primary htn, BPH
Can cause first dose orthostatic hypotension
Avoid NSAIDs (may decrease anti-htn effects)
Clonidine (Catapres)
Alpha-2 agonist (centrally acting)
Decreases sympathetic outflow
Used for primary htn, migraine, ADHD, alcohol withdrawal
Can cause sedation, dry mouth, rebound htn
Do not d/c abruptly
Contraindicated w/ anticoagulants
Do not use w/ prazosin, MAOIs, TCAs, CNS depressants
Twice daily dosing w/ larger dose at bedtime
Metoprolol (Lopressor)
Cardioselective beta-1 blocker
Decreased ino- chron- dromotrope
Used for htn, angina, tachydysrhythmias, HF, MI
Also used for hyperthyroidism, migraines, stage fright, pheochromocytoma, glaucoma
Can cause bradycardia, decreased CO, AV block, orthostatic hypotension
Do not d/c abruptly
Propranolol (Inderal)
Nonselective beta blocker
Used for htn, angina, dysrhythmias, migraines
Causes bronchoconstriction - avoid w/ asthma
Can cause fatigue, bradycardia, hypotension
Inhibits glycogenolysis (hypoglycemia, symptoms may be masked)
Take w/ food to increase absorption
Nitroprusside (Nitrostat)
Vasodilator
Used for hypertensive emergencies
Can cause hypotension, cyanide poisoning
Do not administer in same infusion w/ other meds, may be light brown color, protect from light
Digoxin (Lanoxin)
Cardiac glycoside
Positive inotrope, negative chronotrope and dromotrope
Used for HF, a-fib
Can cause dysrhythmias, bradycardia, GI effects (EARLY), vision changes (EARLY)
Hypokalemia = toxicity; hyperkalemia = decreased effects
Avoid verapamil
Hold if pulse < 60
Therapeutic level = 0.5-2.0ng/mL
Antidote: cholestyramine or Digibind
Interacts w/ many meds
Epinephrine (Adrenaline)
Adrenergic agonist (catecholamine)
Alpha-1, beta-1, beta-2
Slows absorption of anesthetics, manages superficial bleeding, decreased nasal congestion, increased BP, treatment of AV bock and cardiac arrest
Can cause htn, dysrhythmias, angina
Avoid MAOIs (prolong effects) ,TCAs
General anesthetics can cause dysrhythmias
Beta blockers block action at beta receptors
Use an IV pump, titrate dose
Antidote: Phentolamine
Dopamine (Intropin)
Adrenergic agonist (catecholamine)
Low dose: dopamine (renal blood vessel dilation)
Moderate: dopamine, beta-1
High: dopamine, beta-1, alpha-1 (vasoconstriction)
Used for shock, HF
Can cause dysrhythmias, angina, necrosis w/ extravasation
Diuretics promote beneficial effects of dopamine
Dobutamine (Dobutrex)
Adrenergic agonist (catecholamine)
Beta-1
Used for HF
Can cause increased HR
Nitroglycerin
Organic nitrate
Dilates veins and decreases venous return
Used for angina
Can cause headache, orthostatic hypotension, reflex tachycardia
Tolerance can develop
Contraindicated w/ head injury
Avoid alcohol, Viagra
Cautions w/ anti-htn meds
Ranolazine (Ranexa)
Antianginal
Lowers cardiac oxygen demand
Used for angina in combination w/ amlodipine (Norvasc), a beta blocker, or an organic nitrate
Can cause QT prolongation, elevated BP
Avoid grapefruit juice, HIV protease inhibitors, macrolides, azole antifungals, verapamil
Can increase levels of dig and simvastatin
Procainamide (Pronestyl)
Quinidine
Anti-dysrhythmic
Can cause SLE, neutropenia, QT prolongation, hypotension
Lidocaine (Xylocaine)
Anti-dysrhythmic, local anesthetic
Can cause drowsiness, seizures, respiratory arrest, hypotension, cardiosuppression
Propafenone (Rythmol)
Anti-dysrhythmic
Can cause bradycardia, HF, dizziness
Amiodarone (Cordarone)
Anti-dysrhythmic
Can cause pulmonary toxicity, sinus bradycardia, AV block, visual disturbances, liver and thyroid dysfunction, GI effects, phlebitis, hypotenson
Adenosine (Adenocard)
Anti-dysrhythmic
Causes transient asystole
Used to convert SVT to normal sinus rhythm
Can cause sinus bradycardia, hypotension, dyspnea, facial flushing
Rapid IV push followed by saline bolus
Half life of 8-10 seconds
Gemfibrozil (Lopid)
Antilipemic (fibrate)
Decreased triglycerides, increases HDL
Can cause GI distress, gallbladder stones, myopathy, hepatotoxicity
Increases risk of bleeding w/ Coumadin
Take 30 min before breakfast and dinner
Atorvastatin (Lipitor)
Antilipemic (HMG CoA reductace inhibitor)
Decrease LDL, increase HDL
Protects against MI and stroke in diabetics
Can cause hepatotoxicity, myopathy, peripheral neuropathy
Rosuvastatin: avoid in Asians
Risk of rhabdo w/ fibrates, ezetimibe
Grapefruit juice can increase levels
Take in evening
Ezetimibe (Zetia)
Antilipemic (cholesterol absorption inhibitor)
Help lower LDL w/ modified diet
Can combine w/ statin
Can cause hepatitis, myopathy
Levels increased w/ cyclosporine
Colesevelam (WelChol)
Colestyramine (Questran)
Antilipemic (bile-acid sequesterants)
Decrease LDL
Can cause GI distress, decreased absorption of fat-soluble vitamins, constipation
Take other meds 1 hour before or 4 hours after
Take w/ food or add powder to 4-8oz fluid
Niacin
Antilipemic
Decrease LDL and triglyerides
Can cause GI distress, facial flushing, hyperglycemia, hepatoxicity, hyperuriemia
Take aspirin 30 minutes prior to prevent flushing
Heparin
Enoxaparin (Lovenox)
Anticoagulant
Inhibits formation of fibrin
Used to prevent clotting (stroke, DVT, PE, prophylaxis, DIC)
Must be given IV or subQ
Can cause hemorrhage, heparin-induced thrombocytopenia (HIT)
Antidote: protamine sulfate
Avoid aspirin, NSAIDs
Monitor aPTT (60-80 seconds)
Warfarin (Coumadin)
Anticoagulant
Antagonizes vitamin K
Used for DVT, a-fib or prosthetic heart valves, prevention of MI or stroke
Can cause hemorrhage, hepatitis
Antidote: vitamin K
Monitor INR (2-3)
Aspirin (Ecotrin)
Antiplatelet
Used to prevent MI, stroke
Can cause GI effects, hemorrhagic stroke, prolonged bleeding, tinnitus
Do not give to children or adolescents
Avoid NSAIDs, anticoagulants
May decrease action of beta blockers
Corticosteroids may decrease aspirin effects and increase risk for GI bleed
Caffeine may increase absorption
Abciximab (ReoPro)
Antiplatelet
Used to prevent MI, stroke
Used in acute coronary syndromes
Can cause hypotension, bradycardia, prolonged bleeding
Avoid NSAIDs, anticoagulants
Clopidogrel (Plavix)
Antiplatelet
Used to prevent MI, stroke
Can cause prolonged bleeding
Avoid NSAIDs, anticoagulants
Pentoxifylline (Trental)
Antiplatelet
Used to prevent MI, stroke
Used for intermittent claudication
Can cause N/V
Avoid anticoagulants
May increase levels of theophylline
Streptokinase (Streptase)
Alteplase (Activase, tPA)
Thrombolytic
Dissolves clots that have already formed
Used for acute MI, DVT, PE, ischemic stroke (alteplase)
Can cause serious risk of bleeding, hypotension, allergic reaction
Avoid NSAIDs, anticoagulants
Must be used w/in 4-6 hours of onset
Continuous monitoring
Antidote: aminocaproic acid (Amicar)
Epoetin alfa (Epogen)
Erythropoietic growth factor
Used for anemia w/ chronic renal failure, chemo
Can cause htn (elevated Hct), increased risk of stroke or MI (Hgb > 12)
Filgrastim (Neupogen)
Leukopoietic growth factor
Used for neutropenia (cancer)
Can cause bone pain, leukocytosis (WBC > 100,000)
Sargramostim (Leukine)
Granulocyte macrophage CSF
Stimulates bone marrow to produce WBCs
Used after bone marrow transplant
Can cause diarrhea, weakness, malaise, bone pain, leukocytosis, thrombocytosis
d/c for ANC > 20,000, WBC > 50,000, platelets > 500,000
Oprelvekin (Neumega, Interleukin -11)
Thrombopoietic growth factor
Used during chemotherapy
Can cause fluid retention, dysrhythmias, blurred vision, allergic reaction
Ranitidine (Zantac)
Cimetidine (Tagamet)
Famotidine (Pepcid)
H2 receptor antagonist
Used for PUD, GERD
Combine w/ antibiotics for H. pylori
Tagamet may decrease libido and cause impotence; may cause lethargy, depression, confusion in older adults; may increase levels of warfarin, phenytoin, theophylline, lidocaine
May promote bacterial colonization due to decreased gastric acidity
Do not take antacids w/in one hour
Omeprazole (Prilosec)
Proton pump inhibitor
Inhibits enzyme that produces gastric acid
Used for PUD, GERD
Insignificant side effects w/ short term treatment
Long term use increases risk of gastric cancer and osteoporosis
May increase levels of dig
Take once a day prior to eating in the morning
Monitor for GI bleeding
Sucralfate (Carafate)
Mucosal protectant
Coats and protects ulcer (up to 6 hours)
Used for duodenal ulcers
Increase fiber and fluids to prevent constipation
No systemic effects
May interfere w/ absorption of phenytoin, dig, warfarin, cipro
Antacids interfere w/ absorption
Take on empty stomach (one hour before meals and bedtime)
Aluminum hydroxide (Amphojel)
Antacid
Neutralize gastric acid
Used to treat PUD, relieve GERD symptoms
Al and Ca can cause constipation
Mg can cause diarrhea, toxicity w/ renal impairment
Na results in fluid retention
Aluminum hydroxide can lead to hypophosphatemia
Al compounds bind to warfarin and tetracycline
Take w/ 8 oz water or milk
Take other meds one hour before or after
Misoprostol (Cytotec)
Prostaglandin E analog
Used w/ NSAIDs to prevent gastric ulcers
Can induce labor
Can cause diarrhea, abdominal pain, dysmenorrhea, spotting
Take w/ meals and at bedtime
Dexamethasone (Decadron)
Glucocorticoid
Antiemetic used for chemo-induced N/V
Aprepitant (Emend)
Substance P antagonist
Combine w/ glucocorticoid or serotonin antagonist
Has extended duration of action
Can cause fatigue, diarrhea, dizziness, liver damage
Ondansetron (Zofran)
Serotonin antagonist
Used for emesis related to chemo, radiation, postop
Can cause headache, diarrhea, dizziness
Prochlorperazine (Compazine)
Metoclopramide (Reglan)
Promethazine (Phenergan)
Dopamine antagonist
Used for emesis related to chemo, opioids, postop
Can cause EPS (admin Benadryl), hypotension, sedation, anticholinergic effects
Dronabinol (Marinol)
Cannabinoid
Used for chemo N/V and as an appetite stimulant in AIDS
Can cause dissociation/dysphoria, hypotension, tachycardia
Scopolamine (Transderm Scop)
Anticholinergic
Used for motion sickness
Can cause sedation, anticholinergic effects
Dimenhydrinate (Dramamine)
Hydroxyzine (Vistaril)
Antihistamine
Used for motion sickness
Can cause sedation, anticholinergic effects
Psyllium (Metamucil)
Bulk-forming laxative
Softens fecal mass and increases bulk
Docusate sodium (Colace)
Surfactant laxative
Lower surface tension of stool to allow water in
Used for constipation during pregnancy, from opioid use, w/ hemorrhoids
Bisacodyl (Dulcolax)
Stimulant laxative
Stimulates peristalsis
Used for colooscopy prep, short term use for constipation
Magnesium hydroxide (Milk of Magnesia)
Osmotic laxative
Draw water into the intestine
Low dose - to prevent painful elimination (hemorrhoids)
High dose - for colonoscopy pre
Also used for rapid evacuation after poisoning or helminth therapy
Can lead to Mg toxicity
May cause dehydration
Diphenoxylate plus atropine (Lomotil)
Antidiarrheal
Decrease intestinal motility
Does not affect CNS at recommended doses
Atropine discourages abuse (anticholinergic side effects)
Loperamide (Imodium)
Antidiarrheal
Meperidine analog
Not a controlled substance
Metoclopramide (Reglan)
Prokinetic agent
Controls N/V by blocking dopamine and serotonin receptors; augments ACh
Used for postop and chemo N/V, management of GERD and gastroparesis
Can cause EPS (admin Benadryl), sedation, diarrhea
Avoid CNS depressants, opioids, anticholinergic
Alosetron (Lotronex)
Used for IBS-D in women that has lasted > 6 months
Blocks 5-HT3 receptors resulting in firm stool and decrease in urgency and frequency of defecation
Can cause constipation
Lubiprostone (Amitiza)
Used for IBS-C and chronic constipation
Increases fluid secretion in intestine, promotes motility
Can cause diarrhea, nausea (take w/ food)
Sulfasalazine (Azulfidine)
5-aminosalicylate,, DMARD
Decrease inflammation by inhibiting prostaglandin synthesis
Used for IBD (Crohn's, UC), RA
Can cause agranulocytosis, hemolytic and macrocytic anemia,, hepatic dusfunction, bone marrow suppression
Methotrexate (Rheumatrex)
Cytotoxic agent (antimetabolite), DMARD
Folic acid analog
Slows RA, antineoplastic (stops cell reproduction), organ rejection
Can cause increased risk for infection, hepatic fibrosis, bone marrow suppression, GI ulcers, N/V, hyperuricemia/renal damage, fetal death
Protect skin from sunlight
NSAIDs, salicylates, sulfonamides can increase toxicity
May reduce dig level
Take on an empty stomach, once per week
Antidote: leucovorin
Hydroxychloroquinone (Plaquenil)
Antimalarial, DMARD
Used for RA
Can cause retinal damage
Etanercept (Enbrel)
Infliximab (Remicade)
DMARD
Used for RA
Can cause irritation at injection site, risk of infection (TB), severe skin reactions, HF, blood dyscrasias
Etanercept: avoid live vaccines
Aurothioglucose (Solganal)
Gold salt, DMARD
Used for RA
Can cause renal toxicity, blood dyscrasias, hepatitis, GI discomfort
Toxicity: severe pruritis, rash, stomatitis
Penicillamine (Cuprimine)
DMARD
Used for RA
Can cause bone marrow suppression
Toxicity: severe pruritis, rash
Cyclosporine (Sandimmune)
DMARD, IL-2 suppressant
Used for RA, organ rejection
Can cause risk for infection, hepatotoxicity, nephrotoxicity, hirsutism
Avoid grapefruit juice
Decreases levels: phenytoin, phenobarbital, rifampin, carbamazepine, trimethoprim-sulfamethoxazole
Increases levels: ketoconazole, erythromycin, amphotericin B
Amphotericin B, aminoglycosides, NSAIDs increase risk of nephrotoxicity
Calcium citrate (Citracal)
Ca supplement
Can cause hypercalcemia (> 10.5mg/dL) - tachycardia, elevated BP, bradycardia, hypotension, muscle weakness, constipation, N/V
Glucocorticoids reduce Ca absorption
Raloxifene (Evista)
Selective estrogen receptor modulator
Decreases bone resorption
Used for postmenopausal osteoporosis, protect against breast cancer
Increases risk of PE, DVT
Can cause hot flashes
Should consume adequate Ca and vit D, perform weight-bearing exercise
Alendronate sodium (Fosamax)
Bisphosphonate
Decrease action of osteoclasts
Used for osteoporosis, hyperparathyroidism
Can cause esophagitis, GI disturbances, musculoskeletal pain, visual disturbances, osteonecrosis of the jaw, risk of hyperparathyroidism
Take on empty stomach in early morning w/ at least 8oz water, wait 2 hours to take antacids or Ca, avoid lying down for 30 minutes
Calcitonin (Fortical)
Inhibits osteoclasts
Used for osteoporosis, hyperparathyroidism
Can cause nausea, nasal dryness and irritation (intranasal)
Contraindicated w/ allergy to fish protein
Can decrease lithium levels
Monitor for hypocalcemia (Chvostek's or Trousseau's sign)
Encourage diet high in Ca and vit D
Morphine sulfate
Opioid agonist
Produces analgesia, respiratory depression, euphoria, sedation, decreased GI motility
Can also cause urinary retention, orthostatic hypotension, cough suppression, biliary colic, emesis
Opioid overdose triad: coma, respiratory depression, pinpoint pupils
Caution w/ head injuries
Meperidine: lowers seizure threshold
Antidote: naloxone
Butorphanol (Stadol)
Opioid agonist-antagonist
Low potential for abuse, less respiratory depression, less analgesic effect
Do not use w/ opioid agonists
Do not use w/ patient that is dependent on opioids
Naloxone (Narcan)
Opioid antagonist
Used to treat opioid overdose
Half-life is less than half-life of narcotic
Titrate to reduce respiratory depression w/o full reversal of pain management
Rapid infusion may cause htn, tachycardia, N/V
Colchicine (Colgout)
Anti-gout med
Used for acute gout attacks
Can cause GI distress, thrombocytopenia, bone marrow suppression, hepatic necrosis
Take w/ food (Jason says empty stomach!)
Avoid aspirin, loop diuretics, alcohol
Allopurinol (Zyloprim)
Anti-gout med
Inhibits uric acid production
Can cause hypersensitivity reaction, renal injury, hepatitis, N/V
Slows metabolism of warfarin
Ergotamine (Ergostat)
Ergot alkaloid (anti-migraine)
Used to abort a migraine
Can cause N/V (admin Reglan), ergotism (muscle pain, paresthesias in fingers and toes, cold pale extremities), physical dependence, fetal abortion
Sumatriptan (Imitrex)
Serotonin receptor agonist (anti-migraine)
Used to abort a migraine
Can cause chest pressure, angina, vertigo
Do not use w/ MAOIs
Divalproex (Depakote ER)
Anticonvulsant (anti-migraine)
Can cause neural tube defects, liver toxicity, pancreatitis
Do not use w/ benzodiazepines
Lispro (Humalog)
Rapid-acting insulin
Onset < 15 min
Peak 30-60 min
Duration 3-4 hours
Regular (Humulin R)
Short-acting insulin
Onset 30-60 min
Peak 2-3 hours
Duration 5-7 hours
NPH (Humulin N)
Intermediate-acting insulin
Onset 1-2 hours
Peak 4-12 hours
Duration 18-24 hours
Glargine (Lantus)
Long-acting insulin
Onset 1 hour
Peak (none)
Duration 10-24 hours
Tolbutamide (Orinase)
Glipizide (Glucotrol)
Oral hypoglycemic (sulfonylurea)
Results in insulin release from pancreas
Can cause hypoglycemia
Glipizide: disulfiram reaction
Take 30 minutes before meal
Repaglinide (Prandin)
Oral hypoglycemic (meglitinide)
Results in insulin release from pancreas
Can cause hypoglycemia
Avoid gemfibrozil
Eat w/in 30 minutes, 3x/day
Metformin (Glucophage)
Oral hypoglycemic (biguanide)
Reduces production of glucose in liver
Increases muscles' glucose uptake and use
Also used to treat polycystic ovary syndrome
Can cause GI effects, B12 and folic acid deficiency, lactic acidosis
Acute renal failure w/ concurrent use of iodine contrast media
Take w/ breakfast/dinner, or dinner
Rosiglitazone (Avadia)
Oral hypoglycemic (thiazolidinediones/glitazones)
Decreases insulin resistance
Results in increased glucose uptake and decreased glucose production
Can cause fluid retention, elevated LDL, hepatotoxicity
Take w/ or w/o food
Acarbose (Precose)
Oral hypoglycemic (alpha glucosidase inhibitor)
Slows carbohydrate absorption and digestion
Can cause intestinal effects, risk for anemia (decreased iron absorption), hepatotoxicity (long term use)
Take w/ first bite of food (3x/day)
Sitagliptin (Januvia)
Oral hypoglycemic (gliptin)
Augments incretin hormones (promotes insulin release and decreases glucagon secretion)
Lowers fasting and postprandial blood glucose levels
Generally well tolerated
Take once a day w/ or w/o food
Pramlintide (Symlin)
Amylin mimetic (hypoglycemic, subQ)
Decreases postprandial glucose levels (decreased gastric emptying, inhibits glucagon, satiety)
May be used w/ insulin (do not mix)
Oral medication absorption is delayed (stagger one hour before or 2 hours after)
Exenatide (Byetta)
Incretin mimetic (hypoglycemic, subQ)
Lowers fasting and postprandial blood glucose
Promotes insulin release, decreases glucagon, slows gastric emptying
Do NOT use w/ insulin
Can cause N/V/D, pancreatitis
Oral medication absorption is delayed, esp. oral contraceptives and antibiotics (stagger one hour before or 2 hours after)
Glucagon
Hyperglycemic agent
Increases blood glucose levels
Turn patient to left side after admin (N/V)
Levothyroxine (Synthroid)
Thyroid hormone
Synthetic T4
Can cause signs of hyperthyroidism
Stagger binding agents, antacids, Fe and Ca supplements 3 hours
Take before breakfast daily
Must take for life, do not switch brands
Propylthiouracil (PTU)
Antithyroid medication
Block synthesis of thyroid hormones
Can cause signs of hypothyroidism, agranulocytosis
May increase levels of anticoagulants and digoxin
Somatropin (Genotropin)
Growth hormone
Stimulates overall growth
Can cause hyperglycemia, hypothyroidism
Avoid glucocorticoids
Vasopression (Pitressin)
Desmopressin (DDAVP)
ADH hormone
Promote reabsorption of water and vasoconstriction
Used for diabetes insipidus and during cardiac arrest (Vasopression)
Can cause reabsorption of too much water, MI from vasoconstriction
Hydrocortisone (Hydrocortone)
Prednisone, Dexamethasone
Glucocorticoid
Adrenal hormone replacement
Used for adrenocortical insufficiency (Addison's), cancer, inflammation, allergic reactions
Can cause osteoporosis, adrenal suppression, peptic ulcer, infection
Must taper doses
Fludrocortisone acetate (Florinef)
Mineralocorticoid
Adrenal hormone replacement
Used for adrenal insufficiency
Can cause htn, edema, HF, hypokalemia
Must taper doses
Cytarabine (Cytosar-U)
Cytotoxic antimetabolite
Inhibits RNA/DNA synthesis
Can cause liver disease, pulmonary edema, arachnoiditis (admin dexamethasone)
May reduce dig level
Do not use w/ gentamicin
Monitor for neurotoxicity (nystagmus)
Mercaptopurine (Purinethol)
Cytotoxic antimetabolite
Interrupts RNA/DNA synthesis
Can cause liver toxicity, mucositis, gastric ulcers
Reduce dosage w/ allopurinol
May reduce action of warfarin and pancuronium
Doxorubicin (Doxil)
Antitumor antibiotic
Binds to DNA and alters its structure
Can cause bone marrow suppression, N/V alopecia, acute cardiac toxicity/dysrythmias
Extravasation causes severe tissue damage
Discolors urine (orange-red)
Vincristine (Oncovin)
Antimitotic (cytotoxic antineoplastic)
Can cause peripheral neuropathy, alopecia
Extravasation causes severe tissue damage
Antidote: hyaluronidase
Do not give intrathecally
Paclitaxel (Taxol)
Antimitotic (cytotoxic antineoplastic)
Can cause anaphylaxis, bone marrow suppression, bradycardia, heart block, MI, alopecia
Do not use w/ hypersensitivity to castor oil
Cyclophosphamide (Cytoxan)
Alkylating agent (cytotoxic antineoplastic)
Kills rapidly growing cells by interrupting DNA/RNA synthesis
Can cause bone marrow suppression, N/V, acute hemorrhagic cystitis, alopecia
Carmustine (BiCNU)
Alkylating agent (cytotoxic antineoplastic)
Kills rapidly growing cells by interrupting DNA/RNA synthesis
Crosses blood-brain barrier
Can cause bone marrow suppression, N/V, pulmonary fibrosis, liver/kidney toxicity
Cisplatin (Platinol-AQ)
Alkylating agent (cytotoxic antineoplastic)
Kills rapidly growing cells by interrupting DNA/RNA synthesis
Can cause bone marrow suppression, N/V, renal toxicity, hearing loss
Topotecan (Hycamtin)
Irinotecan
Topoisomerase inhibitor (cytotoxic antineoplastic)
Interrupts DNA synthesis
Can cause bone marrow suppression, N/V, alopecia, cholinergic diarrhea
Antidote: atropine
Asparaginase (Elspar)
Antineoplastic
Interrupts DNA in leukemia cells
Can cause N/V, hypersensitivity reaction, alopecia, liver and pancreas toxicity, renal toxicity
Hydroxyurea (Hydrea)
Antineoplastic
Interrupts DNA synthesis
May cross blood-brain barrier
Can cause N/V, bone marrow suppression
Procarbazine (Matulane)
Antineoplastic
Interrupts DNA/RNA synthesis
May cross blood-brain barrier
Can cause N/V, bone marrow suppression, peripheral neuropathy
Leuprolide (Lupron)
Prostate cancer medication
Hormonal agent
Testes stop producing testosterone
Can cause hot flushes, decreased libido, decreased bone density, arrhythmias, pulmonary edema
Increase Ca and vit D intake
Prostate symptoms may worsen at beginning of treatment
Flutamide (Eulexin)
Prostate cancer medication
Hormonal agent
Blocks androgen receptors
Can cause thrombocytopenia, gynecomastia, N/V/D, hepatitis
May increase effects of warfarin
Tamoxifen (Nolvadex)
Breast cancer medication
Hormonal agent
Stops growth of estrogen-dependent breast cancer cells
Can cause endometrial cancer, hypercalcemia, N/V, PE, hot flushes, vaginal discharge or bleeding
Increase Ca and vit D intake
Interferon alpha
Biologic response modifier
Increases immune response, decreases production of cancer cells
Used for hairy cell leukemia, CML, malignant melanoma, Kaposi's syndrome
Can cause flu-like symptoms, bone marrow suppression, hypotension, edema, peripheral neuropathy, skin rashes
Tobramycin Sulfate contraindicated in:
Ibuprofen (Motrin)
Metformin (Glucophage) and glipizide (Glucotrol) for diabete mellitus. Nurse check what lab:
HbA1c of below 7% for diabetics
Warfarin antidote:
Vitamin K
Pancrelipase (Pancrease) teaching plan:
Take at each meal and snack.
Levothyroxine (Synthroid) effective if:
TSH 0.5-2 mircounits/mL
T4 and T3 Value
t3: 75-220 ng/dL
t4: 4-11 mcg/dL
Prazosin (Minipress) teaching:
Move slowly from sitting to standing.
Phenytoin (Dilantin) teaching:
Hirsutism, avoid alcohol and antihistamines, double vision
Enalapril (Vasotec) and spironolactone (Aldactone) adverse effects:
Hyperkalemia because its a ACE-inhibitor and K-sparing diuretic.
Methotrexate (Rheumatrex) for Rheumatoid arthritis teaching:
Report sores in mouth, take once a week [oral or injection], 4-6 weeks to work.
Mannitol (Osmitrol) effective:
Urine output increases
Morphine Sulfate following thoracic procedure. What indicates client pain being managed:
Client able to breathe deeply and cough.
Amitriptyline (Elavil) adverse effects:
Urinary retention.
Magnesium Sulfate toxicity signs:
Decrease level of consciousness, CNS depression
Ferrous Sulfate enhance absorption:
Asorbic Acid
Sotalol Hydrochloride (Betapace) teaching plan:
Decrease heart rate.
Patient on Insulin Lispro and prescribed Metoprolol (Lopressor) for HTN. Nurse should observe what signs for hypoglycemia:
Sweating
Nitroglycerin SL teaching:
Lie down, check BP, relief in 1-3 mins, monitor for headache.
Allopurinol (Zyloprim) contraindications:
Warfarin
Atovastain (Lipitor) nurse should monitor:
CK-Creatinine Kinase
Exercise induced asthma:
Cromolyn sodium (Intal)
Furosemide (Lasix) withhold:
Potassium level
Insulin glargine (Lantus) type 1 diabetes mellitus teaching plan:
DO NOT MIX in syringe, adminster at bedtime, clear, don't need to shake
Colesevelam (WelChol) teaching plan:
Other medication 1 hour or 4 hours after, taken with food or water, high fiber diet.
Levothyroxine (Synthroid) breastfeeding:
Take after breast feeding.
Fluoxetine (Prozac) teaching plan:
Don't take St. John's Wort, may get rash, Acetaminophen instead of Ibuprofen.
Digoxin (Lanoxin) patient experiences Dysrhythmias:
Furosemide (Lasix) lead to hyperkalemia causes dysrhythmias.
Ceftriaxone (Rocephin) postop and notices Uticardia and dyspnea:
Discontinue infusion
Ketorolac (Toradol) teaching plan:
Check for bruising, Take with food.
Risedronate (Actonel) for osteoporosis teaching plan:
Sit up 30 mins, don't take with milk, take in morning, take on empty stomach.
Albuterol (Proventil) for asthma with montelukast (Singular) teaching:
Take montelukast at night
Pilocarpine (Pilocar) eye drops teaching:
Don't drive until vision clears, cause brow pain, take for rest of life, messes with the rest of the body
Required Digoxin measurements:
Peak and trough
Naloxone (Nacar) Antidote:
Observe for bleeding, Assess client for nausea and vomiting, check pain frequently, tachycardia, repeat dose every 2-3 minutes.
Fluticasone propionate (Flovent) adverse:
Candidasies of the mouth, dysphonia.
Trimethropim/sulfamethoxazole (Barctim DS) teaching:
Drinking 8-10 glasses of water
Gentamicin (Garamycin) side effect:
Ototoxicity
Telephone prescription from provider. The Nurse:
Reads the prescription back to the provider.
Seizure disorder. Patient should:
Keep a seizure chart.
Potassium level:
3.5-5 mEq/L
Potassium level less then 3.5 mEq/L:
Cardiac monitor for cardiac dysrhythmias.
Penicillin allergy requires incident report with what symptom:
S.O.B.
Phenytoin (Dilantin) decreases effectiveness of:
Ethinyl/desogestrel (Oral contraceptive)
Ergotamine (Ergostat) SL for migraine headache:
1 SL tablet at onset of headache.
Digoxin level:
1.0-2.0 ng/mL. Digoxin is toxic at 2.4 give Digoxin immune fab (Diggibind)
Avoid during metronidazole (Flagyl):
Beer can cause disulfiram-reaction (Hypotension, vomiting, weakness)
Captopril (Capoten) cannot be used:
With salt substitue with meal or potassium.
Mannitol (Osmitrol) achieving therapeutic effect:
Decrease intraocular pressure for acute closure glaucoma.
Simvastatin (Zocor) teaching plan:
Report muscle pain, do not take med with grapefruit juice, minimize alcohol intake, life long therapy, take in the evening.
Heparin and warfarin client with 4 times aPPT and INR of 2:
Decrease the heparin.
aPPT (Activated partial thromboplastin time) plasma value:
1.5-2 times the normal
INR (International Normalized Ratio) value:
2.0-3.0. Target of 2.5. Higher the number bleeding disorder. Lower the number clotting disorder.
Oxytocin (Pitocin) by continuious IV, piggy backed into maintenance IV solution. FHR indicates late decelerations. The nurse first:
Discontinue client's IV to reduce contractions.
Bupropion (Zyban) side effects:
Insomnia (Stimulant).
Risedronate (Actonel) to treat osteoporosis. Client teaching:
Take in the morning, sit up 30 mins after taking, take with food, swallow whole.
Haloperidol (Haldol) adverse effects (Used for treating vomiting):
Akathisia (Restlessness).
Oprelvekin (Interleukin 11-WBC) effectiveness:
Increase platelet count in chemotherapy patients.
Baclofen (Lioresal) therapeutic outcome:
Decrease the frequency and severity of muscle spasms (MS).
Epoetin Alfa (Procrit) to treat anemia. Nurse should monitor:
Increased blood pressure and seizures if hematocrit rises too quickly.
Tranylcpromine (Parnate) for depression. Client teaching:
Move slowly when changing position because orthrostatic hypotension can result as a side effect.
Exenatide (Byetta) for type 2 diabetes mellitus. Nurse needs to monitor immediately:
Abdominal pain due to pancreatitis.

Secondary symptom for hyperglycemia: Increased thirst
Hypoglycemia symptoms:
Diaphoresis and Irritability.
Prednisone (Deltasone) for chronic asthma. Nurse monitors:
Blood glucose because steroid increase blood sugar.
NHP insulin and Regular insulin in a single syringe: Clear before cloudy.
1. NPH (Cloudy) insert air
2. Regular (Clear) insert air
3. Draw up regular (Clear)
4. Draw up NPH (Cloudy)
Zidovudine (Retrovir) nurse should monitor:
Hemoglobin level because it can cause anemia.
Timolol (Timoptic) for glaucoma. Client history concern:
Its a Beta Blocker that can worsen bradycardia.
Newborn DTaP injection timeframe:
2 months-1st
6 months- 3rd
15 months- 5th
Newborn Hep B vaccine:
At birth
Warfain for AFIB. Nurse needs to check what prior to injection:
INR value.
Hydroxyurea (Droxia) for sickle cell anemia. Nurse reports what to provider:
Hemoglobin, platelets, neutrophils.
Acetaminophen/oxycodone (Percocet) for breakthrough pain PRN and Acetaminophen every 4 hours. The nurse should:
Notify the provider due to possible overdose.
Sucralfate (Carafate) for PUD:
Form protective barrier around ulcer (mucosal protectant).
Client teaching for Warfain:
Limit green leafy veggies, get blood drawn regularly, notify doctor if you bleed of bruise easily, and do not take Aspirin or Tylenol.
Pregnant with Pneumonia contraindication:
Deoxycycline (Doxycin), Tetracycline due to adverse effects on bones.
Lisinopril (Zestril) for HTN. The client should monitor:
Dry cough due to build up of bradykinin.
ACE-Inhibitor cause:
Dry cough.
Nitroglycerin (Nitro-Bid IV) for blood pressure:
Lower systolic blood pressure.
Procainamide (Pronestyl) with acute MI and premature ventricular beats. The nurse should withhold if:
QRS (Contraction) widening of more then 50% and long QT intervals (Rest period) indicates cardiotoxictiy.
Tamoxifen (Nolvadex) for breast cancer adverse side effects:
Menstrual irregularity, hot flashes, vaginal discharge.
Beclomenthasone (QVAR) for chronic asthma teaching plan:
Rinse your mouth.
HX of HTN uses OTC oral decongestants for nasal congestion. The nurse advises patient that decongestants:
Constricts blood vessels (Sympathomimetics)
Phenazopyridine HCL (Pyridium) for acute cystitis will:
Urine will turn a red-orange color.
Trimethoprim/sulfamethoxazole (Bactrim DS) side effects:
Vesicular, crusty rash is a sign of Stevens-Johnson syndrome.
(Photosensitivity-Limited sun exposure)
Propylthiouracil (PTU) outcomes:
Decrease T4, decrease heart rate, decrease body temp, weight gain.
Transdermal Nitroglycerin (Minitran) teaching plan:
Take patch off each evening for medication free time of 12-14 before each new patch.
Amoxicillin/calavulaic acid (Augmentin) allergy to penicillin. The nurse should first:
Hold the medication.
Morphine and discharge teaching:
Increase fiber due to possible constipation.
Ampotericin B (Fungizone) for histoplasmosis (Skin) adverse effects:
Fever and chills are signs of infusion reaction.
Aspirin for arthritis. Signs of salicylism:
Tinnitus, sweating headache, dizziness.
Breakthrough pain. 8 of 10 on scale.
Hydromorphone (Dilaudid) pure opioid for sever pain.
Methylphenidate (Ritalin) for ADHD intervention in adverse effects:
Maintain age-appropriate weight.
Sumatriptan (Imitrex) patient teaching:
Use medication upon first sign of headache. Should dissipate 30-50 mins.
*Up to 2 dose after 2 hours of initial dose.
Side effect: Tightness of chest
PCA of Morphine Sulfate, patient Resp. 10/min, unresponsive to touch. Nurse first:
Administer NarCan into patient IV.
Beginning Prednisone (Deltasone) therapy for acute bronchitis. Patient needs vaccine:
Wait until complete therapy due to glucocorticoids reducing antibody response of live vaccine. Increase risk on infection.
Ferrous Sulfate teaching plan:
Black stools are common, take on empty stomach for absorption, no bruising.
Phenytoin (Dilantin) teaching plan:
Tell dentist because drug can cause gingival hyperplasia, report eye movement.
Dilantin level:
10-20 mcg/L
Below 10- Seizures
Above 20- Toxic can cause Nystagmus (Eye movement)
Ranitidine (Zantac) for GERD adverse effects:
Green Sputum from low stomach PH (Pneumonia)
Effects oral contraceptives:
Carbamazepine (Tegretol) inactivates oral contraceptives
Isoniazid (INH) for TB adverse effects:
Yellow skin tones (Jaundice)
Hematocrit:
Male: 42-52
Female: 37-47
BUN
10-20
RBC:
Male: 4.7-6.1 billion
Female: 4.2-5.4 billion
WBC:
4,800-10,000
PT (Prothrombin Time):
11-14
Platelets:
150,000-450,000
Hemoglobin:
Male: 13.8-17.2
Female: 12.1-15.1
Neutrophil value:
54-62% of blood
Sodium value:
135-145
Lithium level
0.4-1
TSH value:
0.5-5.0 milli unit/L
Coumadin INR value:
2.0-3.0 INR
Creatine value:
.7-1.5
What drugs cannot be taken with ibuprofen?
Prozac and Trobramycin Sulfate.