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9. Amenorrhea. primary, secondary
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Terms in this set (9)
Definition primary
1)Absence of menses by age 13 without normal growth or secondary sexual development
2)Absence of menses by age 15 years WITH normal growth and development
Further classification
1)With secondary sexual development
-Normal breast and pelvic development
-Normal breast but ABnormal uterine development
2)Without secondary sex
-High FSH(Hyper/hypo)
-Low FSH(hypo/hypo)
Cause 1)->normal breast and pelvic
-Hypothyroidism
-Hyperprolactinemia
-PCOS
-Hypothalamic dysfunction
Cause 1)->abnormal uterine
1)Androgen insens(XY)
2)ANatomic abnormalities(XX)
->Mullerian agenesis
->uterovaginal septum
->imperforate hymen
Cause 2)->high fsh
1) Gonadal dysgenesis
->Turner(abn. sex chrom)
->Normal sex chrom(46xx/xy)
Cause 2)->Low FSH
1)Const.delay(MC)
2)Congenital abn
->kallmann, injury, adenoma
3)Acquired
-DM1, pit tumor, systemic(IBD, JRA)
Secondary amenorrhea
1)With hyperandrogenism
2)Without hyperandrogenism
With causes
1)PCOS
2)Androgen secretion
->Ovarian: tumor, hyperthecosis
->Adrenal-androgen-tumor
3)Late onset CAH
Without causes
1)Hypergonadotropic hypo
->Idiopathi
->Ai->DM1, thyroid
->Addison
->iatro(radiation, cycloph)
2)Hyperprolact
3)Endocrin(hypo/hyper T3)
4) HYPO/HYPO
->pit adenoma, cranpharyngoma, sarcoid, sheehan
5)!! Functional hypothalamic amenorrhea(stress, exercise,anorexia) (MC)
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