13 terms

18.4 mechanisms of hormone action, 18.5 control of hormone secretion

describe the two general mechanisms of hormone action, describe the mechanisms of hormone
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first messenger
when a water soluble hormone binds to its receptor at the outer surface of the plasma membrane it acts as the _____
second messenger
the first messenger ( the hormone) then causes production of a _____ inside the cell where specific hormone stimulated responses take place
lipid soluble hormones
these hormones bind to receptors on the plasma membrane
water soluble hormones
these hormones bind to receptors on the plasma membrane
cAMP (cyclic adenosine monophosphate)
one common second messenger
G protein
the hormone-receptor complex activates a membrane protein called a _______.
adenylate cyclase
the activated G protein in turn activates________
protein kinase
a________ is an enzyme that phosphorylates (adds a phosphate group to) other cellular proteins (such as enzymes).
phosphodiesterase
after a brief period an enzyme called ___________ inactivates cAMP
hormone's blood concentration, abundance of target cell's hormone receptors, influences exerted by other hormones
the responsiveness of a target cell to a hormone depends on (3)
signals from nervous system, chemical changes in blood, other hormones
hormone secretion is regulated by (3)
water soluble hormones
these hormones activate the second messenger system
negative feedback
most hormonal regulation is by what (system)