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superficial, thinner epithelial tissue layer
-composed of stratified keratinized epithelium
-cells = keratinocytes, melanocytes, langerhans, merkel
form fibrous protein keratin, creating 5 layers
-deepest layer of basal cells attach to basal lamina of basement membrane
-basal cells mitotically active = new cells form basal layer, old cells pushed toward skin surface
-3 to 4 weeks for epidermal replication
produce pigment granules melanin for skin color, tanning, protecting against UV radiation
dendritic cells that act as antigen-presenting cells
-like macrophages expressing MHC I/II molecules to phagocytose and process antigens
interface between dermis and epidermis
-separates epithelium from underlying connective tissue
-anchors epithelium to loose connective tissue underneath
-selective filter for molecules moving between layers
deeper layer of connective tissue separates epidermis from subcutaneous tissue
-primary source of nutrition for epidermis
-support with collagen fibers
-contains blood vessels,
-immune cells for phagocytosis, antigen presenting properties
-neurons for sensory perception
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