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8 terms

Skin Structure

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Epidermis
superficial, thinner epithelial tissue layer

-composed of stratified keratinized epithelium
-cells = keratinocytes, melanocytes, langerhans, merkel
Keratinocytes
form fibrous protein keratin, creating 5 layers

-deepest layer of basal cells attach to basal lamina of basement membrane
-basal cells mitotically active = new cells form basal layer, old cells pushed toward skin surface
-3 to 4 weeks for epidermal replication
Melanocytes
produce pigment granules melanin for skin color, tanning, protecting against UV radiation
Langerhans Cells
dendritic cells that act as antigen-presenting cells

-like macrophages expressing MHC I/II molecules to phagocytose and process antigens
Merkel Cells
provide cutaneous sensory information of pain, temperature, touch
Basement Membrane
interface between dermis and epidermis

-separates epithelium from underlying connective tissue
-anchors epithelium to loose connective tissue underneath
-selective filter for molecules moving between layers
Dermis
deeper layer of connective tissue separates epidermis from subcutaneous tissue

-primary source of nutrition for epidermis
-support with collagen fibers
-contains blood vessels,
-immune cells for phagocytosis, antigen presenting properties
-neurons for sensory perception
Subcutaneous Tissue
provides support, insulation, energy storage

-storage site for fat = fat deposits
-connective tissues = fibrous tissues