Infection, toxic chemicals, physical injury, and loss of nutrition all cause cell death, tissue loss, and _____.
As long as cell death continues, the ___ will persist
Healing is a complex process that requires intact vascular supply, inflammation, and proliferation of fibroblasts, endothelial cells, and keratinocytes.
Dermal integritiy depends synthesis of collagen, elastin, and proteoglycans by fibroblasts.
Epidermal repairs requires proliferation and migration of keratinocytes over a fibrin-fibronectin support matrix
Inflammation always is part of the healing process because the macrophage is the essential and most important cell.
Growth Factors (epidermal, platelet-derived, fibroblast, TGF-B) have a role in wound healing by enhancing reepithelialization and granulation tissue