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55 terms

Antigout Agents/ Nonsalicylate NSAIDs/Antirheymatics

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Allopurinol (Aloprim, Zyloprim): Side Effects
GI Upset, headache, drowsiness, rash
Allopurinol (Aloprim, Zyloprim): Indication
treatment of gout, uric acid neuropathy, uric acid stone formation
Allopurinol (Aloprim, Zyloprim): Nursing Consideration
encourage 10-12 glass water/day, Check CBC and renal function tests, initial therapy can increase attacks of gout, full therapeutic effect may require several months, management of patients with leukemia, lymphoma who are receiving chemotherapy that may increase uric acid, monitor liver function tests
Allopurinol (Aloprim, Zyloprim): Patient Teaching
avoid use of alcohol, eating organ meats, gravy, legumes, take with food, don't take vitamin C or iron
Allopurinol (Aloprim, Zyloprim): Pregnancy Category
C
Colchicine (Colcrys): Side Effects
nausea, vomiting, diarrhea, sign of toxicity: abdominal cramp, aganulocytosis, pharyngolaryngeal pain
Colchicine (Colcrys): Indicaiton
treatment and prevention of acute gout attacks, familial Mediterranean fever
Colchicine (Colcrys): Nursing Considerations
has analgesic, anti-inflammatory effects, may be taken without regard to meals, Encourage 101-2 glasses water/day, grapefruit and grapefruit juice should not be consumed
Colchicine (Colcrys): patient Teaching
avoid use of alcohol, eating organ meats, gravy, legumes, always carry medication to treat acute attacks
Colchicine (Colcrys): IV dosing instructions
slowly, do not administer IM/Subq
Colchicine (Colcrys):Pregnancy Category
C
Probenecid (Probalan): Side Effects
nausea, sore gums, anorexia, hypersensitivity, skin rash, hemolytic anemia
Probenecid (Probalan): Indication
Treatment of hyperuricemia associated with gout, gouty arthritis
Probenecid (Probalan): Nursing Considerations
Check BUN, renal function tests, encourage 8-10 glasses water/day, give with milk, food and antacids, may also be used with penicillin to elevate and prolong plasma of penicillin for gonococcal infection,
Probenecid (Probalan): Patient Teaching
avoid use of alcohol, eating organ meats, gravy, legumes, avoid aspirin-containing products; may take acetaminophen
Probenecid (Probalan): Pregnancy Category
B
Diclofenac NA (Voltaren): Side Effeccts
dizzines, blood dyscrasias, headache, nephrotoxicity, hypersensitivity, GI distress, bleeding or ulcer, rash
Diclofenac NA (Voltaren): Indication
used in arthritic conditions, dysmenorrhea, Opthalmic:reduce inflammation after cataract extraction
Diclofenac NA (Voltaren): Nursing Consideration
if dose missed take withing 2 hours, may increase risk of cardiovascular thrombotic events, possible cross-allergy with aspirin and other NSAIDs, may increase risk of elevated liver tests
Diclofenac NA (Voltaren):PO dosing instructions
take with full glass of water and food and remain upright for 30 minutes
Diclofenac NA (Voltaren): Patient Teaching
use sunscreen to prevent photosensitivity
Diclofenac NA (Voltaren): Pregnancy Category
C
Etodolac: Side Effects
nephrotoxicity, nausea, blood dyscrasias, anorexia, dizziness, hypertension, hypersensitivity
Etodolac: Indication
reduces pain of osteoarthritis, rheumatoid arthritis
Etodolac: Nursing Considerations
monitor for signs of toxicity: blurred vision, ringing or roaring in ears, full therapeutic effect may take up to 1 month, may increase risk of cardiovascular thrombotic events, may increase risk of GI bleeding or ulcer, may cause false positive for urinary bilirubin, may cause false positive for ketones in urine
Etodolac: patient Teaching
avoid concurrent use of ASA, NSAIDs, acetaminophen, alcohol
Etodolac: Pregnancy Category
C
Ibuprogen (Advil, Motrin IB): Side Effects
nausea, vomiting, diarrhea, constipation, headache, dizziness, fluid retention, GI bleeding, hives, rash
Ibuprogen (Advil, Motrin IB): Indication
treatment of rheumatoid arthritis/osteoarthritis relief of mild/ moderate pain; antipyretic
Ibuprogen (Advil, Motrin IB): Nursing Considerations
use cautiously with aspirin allergy, monitor for visual disturbances, tinnitus, monitor for increased weight gain, edema, fever, hematuria, arthralgia,
Ibuprogen (Advil, Motrin IB): Patient Teaching
avoid alcohol, take with milk or food,
Ibuprogen (Advil, Motrin IB): Pregnancy Category
C
Indomethacin (Indocin): Side Effects
peptic ulcer, dizziness, bone marrow depression, hypersensitivity, blurred vision, tinnitus, hypertension, drowsiness
Indomethacin (Indocin): Indication
treatment of rheumatoid arthritis/osteoarthritis, acute gout, acute painful shoulder
Indomethacin (Indocin): Nursing Considerations
observe for bleeding problems, may increase risk for cardiovascular thrombotic evetnst, monitor for weight gain
Indomethacin (Indocin): Patient Teaching
use caution with potentially hazardous activites, avoid use with alcohol,aspirin, other NSAIDs,
Indomethacin (Indocin): PO dosing instructions
take with food/milk, encourage upright positions for 15-30 minutes
Indomethacin (Indocin): Pregnancy Category
C
Naproxen NA ( Aleve, Anaprox, Naprosyn): Side Effects
nausea, dizziness, headache, asthma, GI bleeding, Hives
Naproxen NA ( Aleve, Anaprox, Naprosyn): Indications
for mild to moderate pain, treatment of arthritis, primary dysmenorrhea
Naproxen NA ( Aleve, Anaprox, Naprosyn): PO dosing instructions
with food to decrease GI upset, on empty stomach to increase absorption
Naproxen NA ( Aleve, Anaprox, Naprosyn): Nursing Considerations
monitor for signs of toxicity: blurred vision, ringing or roaring in ears, full therapeutic effect may take up to 1 month, monitor for melena, weight gain, arthralgia, hematuria
Naproxen NA ( Aleve, Anaprox, Naprosyn): Patient Teaching
Avoid concurrent use of ASA, steroids, alcohol
Naproxen NA ( Aleve, Anaprox, Naprosyn): Pregnancy Category
C
Piroxicam (Feldene): Side Effects
drowsiness, headache, hypertension, hypersensitivity, GI disturbances, bleeding or ulcer
Piroxicam (Feldene): INdication
for mild to moderate pain, osteoarthritis, rheumatoid arthritis
Piroxicam (Feldene): Po dosing instructions
with food to decrease GI upset, on empty stomach to increase absorption
Piroxicam (Feldene): Nursing Considerations
monitor for signs of toxicity: blurred vision, ringing or roaring in ears, jaundice, full therapeutic effect may take up to 1 month, may icrease risk of cardiovascular thrombotic events
Piroxicam (Feldene):Patient Teaching
take at same time every day, avoid concurrent use of ASA, OTC meds, alcohol
Piroxicam (Feldene): Pregnancy Category
C
Salsalate (Disalcid): Side Effects
nausea, vomiting, GI bleeding, vertigo, heartburn, rash, tinnitus
Salsalate (Disalcid): Indications
for mild to moderate pain, rheumatoid arthritis, and osteoarthritis
Salsalate (Disalcid): Po dosing instructions
can be crushed or taken whole, take with food or milk to decrease GI upset
Salsalate (Disalcid): Nursing Considerations
full therapeutic effect may take 2 weeks, read label on OTC meds, may contain ASA, monitor for signs of toxicity: changes in liver, kidney, eye, ear functions
Salsalate (Disalcid): Pregnancy Category
C