Create an account
Chronic multi-system dz characterized clinically by thickening of the skin dz and accumulation of connective tissue and involvement visceral organs and replace of smooth muscle
GI features associate w scleroderma
esophageal dysmotility, achalasia, bacterial overgrowth, dilation of large intestines, hypomotility of small intestine, malabsorption
What does CREST mean?
C-Calcinosis, R-Raynaud's, E-Esophageal dysmotility, S-Sclerodactyly, T-Telangiectasia
Calcinosis is a condition in which
calcium deposits occur in tissues (usually fingers) PIPs, knees, elbows
How do you distinguish between primary and secondary Raynaud's phenomenon?
nailfold capillaryoscopy (place oil drop on fingernail base look under)
chronic autoimmune disorder charcterize by lymphocytic infiltration of exocrine glands w dry eyes and mouth
Progressive Sjogren's involves?
major organs and progresses into lymphoproliferative dz (malignant lymphoma)
Dx test for Sjogren's?
Schirmer's test (tear production), Bengal stain (corneal stains), ANA +, anti-la (SSB), anti-Ro (SSA)
List the the seronegative spondyloarthropathies
ankylosing spondylitis, reactive arthritis, psoriatic arthritis, enteropathic arthropathy
Ankylosing spondylitis presents w?
chronic lower back pain, young female, morning stiffness x 1 in, improved w exercise
Common extraartiular dz w ankylosing spondylitis
anterior uveitis, tertiary heart block, aortic insufficiency progresses to CHF
Clinical exam of ankylosing spondylitis reveals?
limited spine mobility, obliterans of the lumbar lordosis, minimal trauma
What do spondyloarthropathies have in common?
seronegative, involve lower back, extracurricular, HLA-B27
Please allow access to your computer’s microphone to use Voice Recording.
Having trouble? Click here for help.
We can’t access your microphone!
Click the icon above to update your browser permissions and try again
Reload the page to try again!Reload
Press Cmd-0 to reset your zoom
Press Ctrl-0 to reset your zoom
It looks like your browser might be zoomed in or out. Your browser needs to be zoomed to a normal size to record audio.
Please upgrade Flash or install Chrome
to use Voice Recording.
For more help, see our troubleshooting page.
Your microphone is muted
For help fixing this issue, see this FAQ.
Star this term
You can study starred terms together